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    Ilginatinib

    ACTIVE PHARMA INGREDIENTS

    DEVELOPMENTS

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    01 1NS Pharma

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    NS Pharma

    U.S.A

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    AMWC Asia-TDAC
    Not Confirmed
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    NS Pharma

    U.S.A

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    AMWC Asia-TDAC
    Not Confirmed
    USDMF Inactive-api
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 25731

    Submission : 2012-01-25

    Status : Inactive

    Type : II

     CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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    Looking for 1526932-96-6 / Ilginatinib API manufacturers, exporters & distributors?

    Ilginatinib manufacturers, exporters & distributors 1

    79

    PharmaCompass offers a list of Ilginatinib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Ilginatinib manufacturer or Ilginatinib supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ilginatinib manufacturer or Ilginatinib supplier.

    API | Excipient name

    Ilginatinib

    Synonyms

    Ns-018, 1239358-86-1, 56r994wx4l, 6-n-[(1s)-1-(4-fluorophenyl)ethyl]-4-(1-methylpyrazol-4-yl)-2-n-pyrazin-2-ylpyridine-2,6-diamine, (s)-n-(1-(4-fluorophenyl)ethyl)-4-(1-methyl-1h-pyrazol-4-yl)-n'-(pyrazin-2-yl)pyridine-2,6-diamine, 2,6-pyridinediamine, n2-((1s)-1-(4-fluorophenyl)ethyl)-4-(1-methyl-1h-pyrazol-4-yl)-n6-2-pyrazinyl-

    Cas Number

    1526932-96-6

    Unique Ingredient Identifier (UNII)

    56R994WX4L

    About Ilginatinib

    Ilginatinib is an orally bioavailable, small molecule inhibitor of Janus-associated kinase 2 (JAK2) and Src-family kinases, with potential antineoplastic activity. Ilginatinib competes with ATP for binding to JAK2 as well as the mutated form JAK2V617F, thereby inhibiting the activation of JAK2 and downstream molecules in the JAK2/STAT3 (signal transducer and activator of transcription 3) signaling pathway that plays an important role in normal development, particularly hematopoiesis. In addition, ilginatinib inhibits the Src family tyrosine kinases. This eventually leads to the induction of tumor cell apoptosis. JAK2 is the most common mutated gene in bcr-abl-negative myeloproliferative disorders (MPDs); JAK2V617F is a constitutively activated kinase that activates the JAK/STAT signaling pathway and dysregulates cell growth and function, and its expression transforms hematopoietic cells to cytokine-independent growth.

    Ilginatinib Manufacturers

    A Ilginatinib manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ilginatinib, including repackagers and relabelers. The FDA regulates Ilginatinib manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ilginatinib API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    Ilginatinib Suppliers

    A Ilginatinib supplier is an individual or a company that provides Ilginatinib active pharmaceutical ingredient (API) or Ilginatinib finished formulations upon request. The Ilginatinib suppliers may include Ilginatinib API manufacturers, exporters, distributors and traders.

    click here to find a list of Ilginatinib suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

    Ilginatinib Manufacturers | Traders | Suppliers

    Ilginatinib Manufacturers, Traders, Suppliers 1
    26

    We have 1 companies offering Ilginatinib

    Get in contact with the supplier of your choice:

    1. NS Pharma
    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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