Looking for 1424-27-7 / Acetazolamide Sodium API manufacturers, exporters & distributors?
Acetazolamide Sodium manufacturers, exporters & distributors
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API | Excipient name
Acetazolamide Sodium
Synonyms
Sodium acetazolamide, 1424-27-7, Acetazolamide sodium salt, Acetazolamide sodium [jan], Chebi:31163, N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide monosodium salt
Unique Ingredient Identifier (UNII)
429ZT169UH
About Acetazolamide Sodium
Acetazolamide Sodium is the sodium salt of acetazolamide, a nonbacteriostatic sulfonamide derivative with diuretic and anticonvulsant properties. Acetazolamide is a potent inhibitor of carbonic anhydrase that plays an important role in the control of fluid secretion. Inhibition of this enzyme in the kidney results in a reduction in the availability of hydrogen ions for active transport in the renal tubule lumen, thereby leading to increased bicarbonate and cation excretion, and increased urinary volume. Reduced bicarbonate level in circulation induces reduction of intraocular pressure via osmotic mechanism. The anticonvulsant activity of acetazolamide may contribute to inhibition of carbonic anhydrase in the CNS, which decreases carbon dioxide tension in the pulmonary alveoli, thus increasing arterial oxygen tension.
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For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.