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    Viltolarsen

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    Anhui Ribobay Pharmaceutical Co.,Lt...

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    Viltolarsen

    About the Company : Anhui Ribobay Pharmaceutical Co., Ltd., known as Ribobay, was established in August 2021 as a fully owned subsidiary of General Biol. Situated in the Quanjiao industry Zone in Chuz...

    Anhui Ribobay Pharmaceutical Co., Ltd., known as Ribobay, was established in August 2021 as a fully owned subsidiary of General Biol. Situated in the Quanjiao industry Zone in Chuzhou, within the Nanjing metropolitan area, Ribobay Pharmaceutical specializes in the therapeutic oligonucleotides CXO field. This strategic focus aligns with General Biol's broader expansion plans for its CXO business, making Ribobay a crucial component of the company's ventures in this domain.
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    Looking for 2055732-84-6 / Viltolarsen API manufacturers, exporters & distributors?

    Viltolarsen manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Viltolarsen API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Viltolarsen manufacturer or Viltolarsen supplier for your needs.

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    API | Excipient name

    Viltolarsen

    Synonyms

    Ncnp-01, Gtpl11430, Ns-065

    Cas Number

    2055732-84-6

    About Viltolarsen

    Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is characterized by the production of shortened and partially functional dystrophin protein. Although corticosteroids are effective in slowing disease progression in both DMD and BMD patients, they do not address the underlying molecular pathogenesis. The application of antisense oligonucleotides in DMD patients with specific mutations allows for exon skipping, which retains a productive reading frame and results in the production of truncated BMD-like dystrophin proteins. These shortened forms of dystrophin can restore partial muscle function and slow the progression of DMD. Viltolarsen is a phosphorodiamidate morpholino oligonucleotide (PMO); PMOs are oligonucleotides in which the five-membered ribofuranosyl ring is replaced with a six-membered morpholino ring, and the phosphodiester links between nucleotides are replaced with a phosphorodiamidate linkage. In this manner, PMOs are much less susceptible to endo- and exonucleases and exhibit drastically reduced metabolic degradation compared to traditional synthetic oligonucleotides. Hence, viltolarsen is similar to another PMO, [eteplirsen], which gained FDA approval on September 19, 2016; however, [eteplirsen] is specific for exon 51 skipping while viltolarsen is specific for exon 53 skipping. Viltolarsen was granted accelerated FDA approval on August 12, 2020, based on data showing an increase in dystrophin levels in skeletal muscle of patients treated with viltolarsen; this approval is contingent on further verification in confirmatory trials. Viltolarsen was developed by Nippon Shinyaku Co LTD and is being marketed under the name VILTEPSO.

    Viltolarsen Manufacturers

    A Viltolarsen manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Viltolarsen, including repackagers and relabelers. The FDA regulates Viltolarsen manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Viltolarsen API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Viltolarsen manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.

    Viltolarsen Suppliers

    A Viltolarsen supplier is an individual or a company that provides Viltolarsen active pharmaceutical ingredient (API) or Viltolarsen finished formulations upon request. The Viltolarsen suppliers may include Viltolarsen API manufacturers, exporters, distributors and traders.

    click here to find a list of Viltolarsen suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

    Viltolarsen Manufacturers | Traders | Suppliers

    Viltolarsen Manufacturers, Traders, Suppliers 1
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    We have 1 companies offering Viltolarsen

    Get in contact with the supplier of your choice:

    1. Anhui Ribobay Pharmaceutical Co.,Ltd
    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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