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List of Drug Master Files (JDMF) for Nafamostat Active Pharmaceutical Ingredient (API) submitted to the Review Authority in Japan (PMDA). Original Data : PMDA Database

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01 Ajinomoto Co., Inc. (1)

02 Kanto Chemical Co., Ltd. (2)

03 Katsura Chemical Co., Ltd. (2)

04 Permakem Asia Co., Ltd. (1)

05 Shizuoka Caffeine Industry Co., Ltd. (1)

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01 Japanese Pharmacopoeia nafamostat mesylate (production only) (1)

02 Mesylate nafamostat (1)

03 Mesylate nafamostat - deer (1)

04 Nafamostat mesylate (1)

05 Nafamostat mesylate - deer (1)

06 Nafamostat mesylate -A (1)

07 Nafamostat mesylate -K (1)

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01 Japan (7)

URL Supplier Web Content
226MF10002
1-15-1 Kyobashi, Chuo-ku, Tokyo
2014-01-08
2014-01-08
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220MF10222
3-2-8 Nihonbashi Honmachi, Chuo-ku,...
2021-02-24
2008-11-04
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218MF10299
3-2-8 Nihonbashi Honmachi, Chuo-ku,...
2006-11-06
2006-02-28
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223MF10091
4-15-19 Hibarigaoka, Zama City, Kan...
2011-06-29
2011-06-29
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220MF10201
4-15-19 Hibarigaoka, Zama City, Kan...
2008-09-19
2008-09-19
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220MF10115
129 Suidocho, Aoi Ward, Shizuoka Ci...
2008-04-21
2008-04-21
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217MF11135
7-6 Nihonbashi Odenmacho, Chuo-ku, ...
2006-04-27
2005-12-05
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Looking for 81525-10-2 / Nafamostat API manufacturers, exporters & distributors?

Nafamostat manufacturers, exporters & distributors 1

72

PharmaCompass offers a list of Nafamostat API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Nafamostat manufacturer or Nafamostat supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Nafamostat manufacturer or Nafamostat supplier.

PharmaCompass also assists you with knowing the Nafamostat API Price utilized in the formulation of products. Nafamostat API Price is not always fixed or binding as the Nafamostat Price is obtained through a variety of data sources. The Nafamostat Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Nafamostat

Synonyms

81525-10-2, Nafamostat [inn], Nafamstat, (6-carbamimidoylnaphthalen-2-yl) 4-(diaminomethylideneamino)benzoate, Chembl273264, Y25lq0h97d

Cas Number

81525-10-2

Unique Ingredient Identifier (UNII)

Y25LQ0H97D

About Nafamostat

Nafamostat is a broad-spectrum, synthetic serine protease inhibitor, with anticoagulant, anti-inflammatory, mucus clearing, and potential antiviral activities. Upon administration, nafamostat inhibits the activities of a variety of proteases, including thrombin, plasmin, kallikrein, trypsin, and Cl esterase in the complement system, and factors VIIa, Xa, and XIIa in the coagulation system. Although the mechanism of action of nafamostat is not fully understood, trypsinogen activation in the pancreas is known to be a trigger reaction in the development of pancreatitis. Nafamostat blocks the activation of trypsinogen to trypsin and the inflammatory cascade that follows. Nafamostat may also decrease epithelial sodium channel (ENaC) activity and increase mucus clearance in the airways. ENaC activity is increased in cystic fibrosis. In addition, nafamostat may inhibit the activity of transmembrane protease, serine 2 (TMPRSS2), a host cell serine protease that mediates viral cell entry for influenza virus and coronavirus, thereby inhibiting viral infection and replication.

Nafamostat Manufacturers

A Nafamostat manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Nafamostat, including repackagers and relabelers. The FDA regulates Nafamostat manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Nafamostat API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Nafamostat manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Nafamostat Suppliers

A Nafamostat supplier is an individual or a company that provides Nafamostat active pharmaceutical ingredient (API) or Nafamostat finished formulations upon request. The Nafamostat suppliers may include Nafamostat API manufacturers, exporters, distributors and traders.

click here to find a list of Nafamostat suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Nafamostat JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Nafamostat Drug Master File in Japan (Nafamostat JDMF) empowers Nafamostat API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Nafamostat JDMF during the approval evaluation for pharmaceutical products. At the time of Nafamostat JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Nafamostat suppliers with JDMF on PharmaCompass.

Nafamostat Manufacturers | Traders | Suppliers

Nafamostat Manufacturers, Traders, Suppliers 1
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We have 5 companies offering Nafamostat

Get in contact with the supplier of your choice:

  1. Ajinomoto Company
  2. Kanto Chemical
  3. Katsura Chemical
  4. Nippi
  5. Permachem Asia, Ltd
Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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