The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.
The Loperamide hydrochloride mixture with simethicone Drug Master File in Japan (Loperamide hydrochloride mixture with simethicone JDMF) empowers Loperamide hydrochloride mixture with simethicone API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).
PMDA reviews the Loperamide hydrochloride mixture with simethicone JDMF during the approval evaluation for pharmaceutical products. At the time of Loperamide hydrochloride mixture with simethicone JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.
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