The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.
The ICOSAPENT (EPA ETHYL ESTER) Drug Master File in Japan (ICOSAPENT (EPA ETHYL ESTER) JDMF) empowers ICOSAPENT (EPA ETHYL ESTER) API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).
PMDA reviews the ICOSAPENT (EPA ETHYL ESTER) JDMF during the approval evaluation for pharmaceutical products. At the time of ICOSAPENT (EPA ETHYL ESTER) JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.
click here to find a list of ICOSAPENT (EPA ETHYL ESTER) suppliers with JDMF on PharmaCompass.