loader
Please Wait
Applying Filters...
Close
4

Seqens Seqens

X
menu

    Market Place

    Market Place

    Post Enquiry

    Post Enquiry
    menu

    Technical details about Trientine Hydrochloride, learn more about the structure, uses, toxicity, action, side effects and more

    Client Email Product
    Menu

    Trientine Hydrochloride

    APIs // Active Pharmaceutical Ingredients

    PRICE INFORMATION

    DOSSIERs // Finished Dosage Forms

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    GLOBAL SALES INFORMATION

    MARKET PLACE

    ANALYTICAL SOLUTION(s)

    DIGITAL CONTENT

    PharmaCompass

    PharmaCompass Sponsored Ads

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    2D Structure
    Also known as: Triethylenetetramine dihydrochloride, 38260-01-4, Syprine, Trientine dihydrochloride, Trientine hcl, Mk-0681
    Molecular Formula
    C6H20Cl2N4
    Molecular Weight
    219.15  g/mol
    InChI Key
    WYHIICXRPHEJKI-UHFFFAOYSA-N
    FDA UNII
    HC3NX54582
    An ethylenediamine derivative used as stabilizer for EPOXY RESINS, as ampholyte for ISOELECTRIC FOCUSING and as chelating agent for copper in HEPATOLENTICULAR DEGENERATION.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine;dihydrochloride
    2.1.2 InChI
    InChI=1S/C6H18N4.2ClH/c7-1-3-9-5-6-10-4-2-8;;/h9-10H,1-8H2;2*1H
    2.1.3 InChI Key
    WYHIICXRPHEJKI-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C(CNCCNCCN)N.Cl.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    HC3NX54582
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Syprine

    2. Trien

    3. Trientine

    4. Trientine Dihydrochloride

    5. Triethylenetetramine

    2.3.2 Depositor-Supplied Synonyms

    1. Triethylenetetramine Dihydrochloride

    2. 38260-01-4

    3. Syprine

    4. Trientine Dihydrochloride

    5. Trientine Hcl

    6. Mk-0681

    7. 1,2-ethanediamine, N,n'-bis(2-aminoethyl)-, Dihydrochloride

    8. Triethylene Tetramine Dihydrochloride

    9. Teta

    10. N,n'-bis(2-aminoethyl)-1,2-ethanediamine Dihydrochloride

    11. Hc3nx54582

    12. Nsc-759164

    13. N1,n1'-(ethane-1,2-diyl)bis(ethane-1,2-diamine) Dihydrochloride

    14. Trien Dihydrochloride

    15. Cuprid

    16. 1,2-ethanediamine,n1,n2-bis(2-aminoethyl)-, Hydrochloride (1:2)

    17. Trientine Hydrochloride [usan]

    18. Einecs 253-854-3

    19. Mk 0681

    20. N,n'-bis(2-aminoethyl)ethylenediamine Dihydrochloride

    21. Laszarin

    22. Metalite

    23. Unii-hc3nx54582

    24. Trientine-2hcl

    25. 2,2'-ethylenediiminobis(ethylamine) Dihydrochloride

    26. Syprine (tn)

    27. Trientine Hydrochloride [usan:usp]

    28. Trientinedihydrochloride

    29. Triethyl Enetetramine 2hcl

    30. Schembl506189

    31. Chebi:9706

    32. Chembl3989777

    33. Dtxsid2057863

    34. Amy3335

    35. Tja-250

    36. Mk-681

    37. N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine;dihydrochloride

    38. S6585

    39. Trientine Hydrochloride (jp17/usp)

    40. Trientine Hydrochloride [jan]

    41. Trientine Dihydrochloride [mi]

    42. Akos028109579

    43. Ccg-213505

    44. Nsc 759164

    45. Trientine Hydrochloride [vandf]

    46. Trientine Hydrochloride [usp-rs]

    47. Trientine Dihydrochloride [mart.]

    48. Bs-49370

    49. Trientine Dihydrochloride [who-dd]

    50. Db-049259

    51. Ft-0639448

    52. Trientine Hydrochloride [orange Book]

    53. D00736

    54. E78246

    55. Trientine Hydrochloride [usp Monograph]

    56. 260t014

    57. Q27279855

    58. N1,n1'-(ethane-1,2-diyl)diethane-1,2-diamine Dihydrochloride

    59. N\'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine,dihydrochloride

    60. Trientine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    61. Triethylenetetramine Dihydrochloride, Puriss., 2xcryst., >=99.0% (at)

    62. Trientine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 219.15 g/mol
    Molecular Formula C6H20Cl2N4
    Hydrogen Bond Donor Count6
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count7
    Exact Mass218.1065020 g/mol
    Monoisotopic Mass218.1065020 g/mol
    Topological Polar Surface Area76.1 Ų
    Heavy Atom Count12
    Formal Charge0
    Complexity49.7
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameSyprine
    PubMed HealthTrientine (By mouth)
    Drug ClassesHeavy Metal Chelator
    Drug LabelTrientine hydrochloride is N,N'-bis (2-aminoethyl)-1,2-ethanediamine dihydrochloride. It is a white to pale yellow crystalline hygroscopic powder. It is freely soluble in water, soluble in methanol, slightly soluble in ethanol, and insoluble in chlor
    Active IngredientTrientine hydrochloride
    Dosage FormCapsule
    RouteOral
    Strength250mg
    Market StatusPrescription
    CompanyAton

    2 of 2  
    Drug NameSyprine
    PubMed HealthTrientine (By mouth)
    Drug ClassesHeavy Metal Chelator
    Drug LabelTrientine hydrochloride is N,N'-bis (2-aminoethyl)-1,2-ethanediamine dihydrochloride. It is a white to pale yellow crystalline hygroscopic powder. It is freely soluble in water, soluble in methanol, slightly soluble in ethanol, and insoluble in chlor
    Active IngredientTrientine hydrochloride
    Dosage FormCapsule
    RouteOral
    Strength250mg
    Market StatusPrescription
    CompanyAton

    4.2 Drug Indication

    Cufence is indicated for the treatment of Wilsons disease in patients intolerant to D-Penicillamine therapy, in adults and children aged 5 years or older.

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Chelating Agents

    Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS. (See all compounds classified as Chelating Agents.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Metal Chelator [EPC]; Metal Chelating Activity [MoA]
    5.3 ATC Code

    A16A

    Post Enquiry
    POST ENQUIRY