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    Technical details about Sodium Polystyrene Sulfonate, learn more about the structure, uses, toxicity, action, side effects and more

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    Sodium Polystyrene Sulfonate

    APIs // Active Pharmaceutical Ingredients

    DOSSIERs // Finished Dosage Forms

    GLOBAL SALES INFORMATION

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    PharmaCompass

    Inke S.A: APIs manufacturing plant.

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    2D Structure
    1. Also known as: 4-ethenylbenzenesulfonic acid, 4-styrenesulfonic acid, 28210-41-5, 98-70-4, Polystyrene sulfonate, 4-vinylbenzenesulfonic acid
    Molecular Formula
    C8H8O3S
    Molecular Weight
    184.21  g/mol
    InChI Key
    MAGFQRLKWCCTQJ-UHFFFAOYSA-N
    FDA UNII
    1D1822L42I
    Sodium Polystyrene Sulfonate is a potassium ion exchange resin composed of benzene-diethyl polymer with ethenyl-benzene, sulfonated, sodium salt. Administered as an oral suspension, sodium polystyrene sulfonate lowers serum potassium levels by exchanging its sodium ions for potassium ions. Acting primarily in the large intestine, this agent also exchanges its sodium ions for calcium and magnesium ions, resulting in a decrease in serum calcium and magnesium levels. (NCI04)
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-ethenylbenzenesulfonic acid
    2.1.2 InChI
    InChI=1S/C8H8O3S/c1-2-7-3-5-8(6-4-7)12(9,10)11/h2-6H,1H2,(H,9,10,11)
    2.1.3 InChI Key
    MAGFQRLKWCCTQJ-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C=CC1=CC=C(C=C1)S(=O)(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    1D1822L42I
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Calcium Polystyrene Sulfonate

    2. Calcium Resonium

    3. Kalimate

    4. Kayexalate

    5. Poly(styrene Sulfonate Sodium Salt)

    6. Poly(styrenesulfonate)

    7. Polystyrene Sulfonate

    8. Polystyrene Sulfonic Acid

    9. Polystyrene Sulfonic Acid, Homopolymer, Calcium Salt

    10. Polystyrene Sulfonic Acid, Homopolymer, Sodium Salt

    11. Psso3

    12. Resonium-a

    2.3.2 Depositor-Supplied Synonyms

    1. 4-ethenylbenzenesulfonic Acid

    2. 4-styrenesulfonic Acid

    3. 28210-41-5

    4. 98-70-4

    5. Polystyrene Sulfonate

    6. 4-vinylbenzenesulfonic Acid

    7. Benzenesulfonic Acid, 4-ethenyl-

    8. P-vinylbenzenesulfonic Acid

    9. 1d1822l42i

    10. Polystyrene Sulfonic Acid

    11. Styrene-4-sulphonic Acid

    12. Mfcd00165973

    13. Unii-1d1822l42i

    14. 9080-79-9

    15. Benzenesulfonic Acid, 4-ethenyl-, Homopolymer

    16. Schembl25711

    17. Poly(sodium P-styrenesulfonate)

    18. Sodium Polystyrene Sulfonic Acid

    19. Chembl1490300

    20. Dtxsid5045045

    21. Zinc1841096

    22. Akos024462356

    23. Benzenesulfonic Acid,4-ethenyl-, Homopolymer

    24. Cs-0187639

    25. Ft-0660598

    26. Q3395465

    27. Poly(styrene Sulfonic Acid), M.w. 75,000, 30% W/v Aqueous Solution

    28. Polystyrene Sulfonic Acid (rigid, Macroporous 200-400 Micrometer, 1-2 Mmol/g)

    2.3.3 Other Synonyms

    1. Polystyrene Sulfonic Acid, Homopolymer, Sodium Salt

    2. Poly(styrene Sulfonate Sodium Salt)

    2.4 Create Date
    2005-03-27
    3 Chemical and Physical Properties
    Molecular Weight 184.21 g/mol
    Molecular Formula C8H8O3S
    XLogP31.4
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count2
    Exact Mass184.01941529 g/mol
    Monoisotopic Mass184.01941529 g/mol
    Topological Polar Surface Area62.8 Ų
    Heavy Atom Count12
    Formal Charge0
    Complexity242
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Cation Exchange Resins

    High molecular weight insoluble polymers which contain functional anionic groups that are capable of undergoing exchange reactions with cations. (See all compounds classified as Cation Exchange Resins.)

    Chelating Agents

    Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS. (See all compounds classified as Chelating Agents.)

    4.2 ATC Code

    V - Various

    V03 - All other therapeutic products

    V03A - All other therapeutic products

    V03AE - Drugs for treatment of hyperkalemia and hyperphosphatemia

    V03AE01 - Polystyrene sulfonate

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