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    Technical details about SODIUM FLUORIDE F 18, learn more about the structure, uses, toxicity, action, side effects and more

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    SODIUM FLUORIDE F 18

    APIs // Active Pharmaceutical Ingredients

    DOSSIERs // Finished Dosage Forms

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    DIGITAL CONTENT

    PharmaCompass

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    2D Structure
    1. Also known as: Sodium fluoride f 18, Sodium fluoride-18f, 22554-99-0, Sodium fluoride (na18f), Fluorine f 18 sodium fluoride, Sodium;fluorine-18(1-)
    Molecular Formula
    FNa
    Molecular Weight
    40.990707  g/mol
    InChI Key
    PUZPDOWCWNUUKD-ULWFUOSBSA-M
    FDA UNII
    9L75099X6R
    Sodium Fluoride F-18 is a radiopharmaceutical consisting of the sodium salt of fluorine F 18 fluoride with radioisotopic and bone mineralizing activities. Fluoride binds to calcium ions in hydroxyapatite crystals in bone. The uptake and incorporation of positron-emitting fluorine F 18 fluoride into bone can be imaged using positron emission tomography (PET) or single-photon emission computed tomography (SPECT), allowing visualization of malignant bone lesions in which regional blood flow and bone turnover are increased.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    sodium;fluorine-18(1-)
    2.1.2 InChI
    InChI=1S/FH.Na/h1H;/q;+1/p-1/i1-1;
    2.1.3 InChI Key
    PUZPDOWCWNUUKD-ULWFUOSBSA-M
    2.1.4 Canonical SMILES
    [F-].[Na+]
    2.1.5 Isomeric SMILES
    [18F-].[Na+]
    2.2 Other Identifiers
    2.2.1 UNII
    9L75099X6R
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. Sodium Fluoride F 18

    2. Sodium Fluoride-18f

    3. 22554-99-0

    4. Sodium Fluoride (na18f)

    5. Fluorine F 18 Sodium Fluoride

    6. Sodium;fluorine-18(1-)

    7. Sodium Radiofluoride

    8. Sodium Fluoride, F-18

    9. Sodium Fluoride (18f)

    10. Sodium Fluoride F 18 [usp]

    11. 9l75099x6r

    12. Sodium Fluoride F 18 (usp)

    13. Sodium 18f-fluoride

    14. Sodium Fluoride (f18)

    15. 18f-naf

    16. F-18 Naf

    17. Unii-9l75099x6r

    18. Fluorine 18-labeled Sodium Fluoride

    19. Fluorine, F-18

    20. Fluorine F-18 (tn)

    21. Chembl1200744

    22. Dtxsid001027605

    23. Nsc749126

    24. Nsc-749126

    25. Sodium Fluoride (18f) [who-dd]

    26. Sodium Fluoride F 18 [usp Impurity]

    27. Sodium Fluoride F-18 [orange Book]

    28. D05860

    29. Q27272701

    30. Radiolabeled Fluorine-18 Sodium Fluoride (18f-naf)

    2.4 Create Date
    2008-02-05
    3 Chemical and Physical Properties
    Molecular Weight 40.990707 g/mol
    Molecular Formula FNa
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count1
    Rotatable Bond Count0
    Exact Mass40.990707 g/mol
    Monoisotopic Mass40.990707 g/mol
    Topological Polar Surface Area0 Ų
    Heavy Atom Count2
    Formal Charge0
    Complexity2
    Isotope Atom Count1
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 FDA Pharmacological Classification
    4.1.1 Pharmacological Classes
    Radiopharmaceutical Activity [MoA]; Radioactive Diagnostic Agent [EPC]
    4.2 ATC Code

    V - Various

    V09 - Diagnostic radiopharmaceuticals

    V09I - Tumour detection

    V09IX - Other diagnostic radiopharmaceuticals for tumour detection

    V09IX06 - Sodium fluoride (18F)

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