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    Sivopixant

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    2D Structure
    Also known as: 2414285-40-6, Sivopixant [inn], S0n1veg94i, S-600918, Unii-s0n1veg94i, (2s)-3-[3-[(4-chlorophenyl)methyl]-2,6-dioxo-4-(4-pyridin-2-yloxyanilino)-1,3,5-triazin-1-yl]-2-methylpropanoic acid
    Molecular Formula
    C25H22ClN5O5
    Molecular Weight
    507.9  g/mol
    InChI Key
    SKZQFKBIJUXXCG-INIZCTEOSA-N
    FDA UNII
    S0N1VEG94I
    CHEMBL5084939 is a Unknown drug.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (2S)-3-[3-[(4-chlorophenyl)methyl]-2,6-dioxo-4-(4-pyridin-2-yloxyanilino)-1,3,5-triazin-1-yl]-2-methylpropanoic acid
    2.1.2 InChI
    InChI=1S/C25H22ClN5O5/c1-16(22(32)33)14-31-24(34)29-23(30(25(31)35)15-17-5-7-18(26)8-6-17)28-19-9-11-20(12-10-19)36-21-4-2-3-13-27-21/h2-13,16H,14-15H2,1H3,(H,32,33)(H,28,29,34)/t16-/m0/s1
    2.1.3 InChI Key
    SKZQFKBIJUXXCG-INIZCTEOSA-N
    2.2 Other Identifiers
    2.2.1 UNII
    S0N1VEG94I
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. (2s)-3-(3-((4-chlorophenyl)methyl)-2,6-dioxo-4-(4-pyridin-2-yloxyanilino)-1,3,5-triazin-1-yl)-2-methylpropanoic Acid

    2.3.2 Depositor-Supplied Synonyms

    1. 2414285-40-6

    2. Sivopixant [inn]

    3. S0n1veg94i

    4. S-600918

    5. Unii-s0n1veg94i

    6. (2s)-3-[3-[(4-chlorophenyl)methyl]-2,6-dioxo-4-(4-pyridin-2-yloxyanilino)-1,3,5-triazin-1-yl]-2-methylpropanoic Acid

    7. Compound 28 [pmid: 34587541]

    8. 1,3,5-triazine-1(2h)-propanoic Acid, 3-((4-chlorophenyl)methyl)tetrahydro-alpha-methyl-2,6-dioxo-4-((4-(2-pyridinyloxy)phenyl)imino)-, (alphas,4e)-

    9. Compound 28 (pmid: 34587541)

    10. 1,3,5-triazine-1(2h)-propanoic Acid, 3-((4-chlorophenyl)methyl)tetrahydro-.alpha.-methyl-2,6-dioxo-4-((4-(2-pyridinyloxy)phenyl)imino)-, (.alpha.s,4e)-

    11. (2s)-3-(3-((4-chlorophenyl)methyl)-2,6-dioxo-4-(4-pyridin-2-yloxyanilino)-1,3,5-triazin-1-yl)-2-methylpropanoic Acid

    12. (e/z)-sivopixant

    13. 1640808-39-4

    14. Sivopixant?

    15. Sivopixant (jan/inn)

    16. Chembl5084939

    17. Schembl16309814

    18. Schembl23716843

    19. Gtpl11756

    20. Bdbm271626

    21. Ex-a5402

    22. Akos040757726

    23. Akos040759920

    24. Hy-137451a

    25. Us10065941, Compound I-127

    26. Ac-37122

    27. Da-57909

    28. Ms-29437

    29. Hy-137451

    30. Cs-0138657

    31. Cs-0146664

    32. D12355

    33. G17804

    34. (s,e)-3-(3-(4-chlorobenzyl)-2,6-dioxo-4-((4-(pyridin-2-yloxy)phenyl)imino)-1,3,5-triazinan-1-yl)-2-methylpropanoic Acid

    2.4 Create Date
    2016-02-23
    3 Chemical and Physical Properties
    Molecular Weight 507.9 g/mol
    Molecular Formula C25H22ClN5O5
    XLogP33.8
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count9
    Exact Mass Da
    Monoisotopic Mass Da
    Topological Polar Surface Area124
    Heavy Atom Count36
    Formal Charge0
    Complexity826
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Indication

    Treatment of unexplained or refractory chronic cough