Please Wait
Applying Filters...
menu
    • menu
    Athena Pharmaceutiques is a Partner of Choice for Drug Delivery & Life Cycle Management.

    Virtual Booth

    Contact Supplier

    Kikkoman Biochemifa Company advances global health and safety through precision-driven innovation in biotech and food testing.

    Virtual Booth

    Contact Supplier

    Rusan Pharma: Over 30 years of specializing in the treatment of Addiction and Pain Management.

    Virtual Booth

    Contact Supplier

    TransoPharm USA works in the Sourcing and Management of Active Pharmaceutical Ingredients.

    Virtual Booth

    Contact Supplier

    Moehs Group, a reference company in the production of pharmaceutical active ingredients.

    Virtual Booth

    Contact Supplier

    pharmacompass-2-m-2025-10-20

    Virtual Booth

    An Enquiry

    Menu

    Rimacalib

    ACTIVE PHARMA INGREDIENTS

    PharmaCompass
    Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: Smp-114, 215174-50-8, Rimacalib [inn], Cid 10157465, Bz76j3n815, N'-[3-[(1s)-1-(3-fluoro-4-phenylphenyl)ethyl]-1,2-oxazol-5-yl]morpholine-4-carboximidamide
    Molecular Formula
    C22H23FN4O2
    Molecular Weight
    394.4  g/mol
    InChI Key
    MYTIJGWONQOOLC-HNNXBMFYSA-N
    FDA UNII
    BZ76J3N815
    Rimacalib has been used in trials studying the treatment of Rheumatoid Arthritis (RA).
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N'-[3-[(1S)-1-(3-fluoro-4-phenylphenyl)ethyl]-1,2-oxazol-5-yl]morpholine-4-carboximidamide
    2.1.2 InChI
    InChI=1S/C22H23FN4O2/c1-15(17-7-8-18(19(23)13-17)16-5-3-2-4-6-16)20-14-21(29-26-20)25-22(24)27-9-11-28-12-10-27/h2-8,13-15H,9-12H2,1H3,(H2,24,25)/t15-/m0/s1
    2.1.3 InChI Key
    MYTIJGWONQOOLC-HNNXBMFYSA-N
    2.1.4 Canonical SMILES
    CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C3=NOC(=C3)N=C(N)N4CCOCC4
    2.1.5 Isomeric SMILES
    C[C@@H](C1=CC(=C(C=C1)C2=CC=CC=C2)F)C3=NOC(=C3)/N=C(\N)/N4CCOCC4
    2.2 Other Identifiers
    2.2.1 UNII
    BZ76J3N815
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. N'-(3-((1s)-1-(2-fluoro-4-biphenylyl)ethyl)-1,2-oxazol-5-yl)-4-morpholinecarboximidamide

    2. Smp-114

    2.3.2 Depositor-Supplied Synonyms

    1. Smp-114

    2. 215174-50-8

    3. Rimacalib [inn]

    4. Cid 10157465

    5. Bz76j3n815

    6. N'-[3-[(1s)-1-(3-fluoro-4-phenylphenyl)ethyl]-1,2-oxazol-5-yl]morpholine-4-carboximidamide

    7. N-(3-((1s)-1-(2-fluorobiphenyl-4-yl)ethyl)-1,2-oxazol-5-yl)morpholine-4-carboximidamide

    8. 4-morpholinecarboximidamide, N-(3-((1s)-1-(2-fluoro(1,1'-biphenyl)-4-yl)ethyl)-5-isoxazolyl)-

    9. Smp 114

    10. Sm-114

    11. Unii-bz76j3n815

    12. Schembl4179253

    13. Chembl2107772

    14. Db12571

    15. Hy-100779

    16. Cs-0020416

    17. N'-(3-((1s)-1-(2-fluoro-4-biphenylyl)ethyl)-1,2-oxazol-5-yl)-4-morpholinecarboximidamide

    2.4 Create Date
    2006-10-25
    3 Chemical and Physical Properties
    Molecular Weight 394.4 g/mol
    Molecular Formula C22H23FN4O2
    XLogP33.4
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count5
    Exact Mass394.18050415 g/mol
    Monoisotopic Mass394.18050415 g/mol
    Topological Polar Surface Area76.9 Ų
    Heavy Atom Count29
    Formal Charge0
    Complexity551
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count1
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Protein Kinase Inhibitors

    Agents that inhibit PROTEIN KINASES. (See all compounds classified as Protein Kinase Inhibitors.)