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    Technical details about Rasburicase, learn more about the structure, uses, toxicity, action, side effects and more

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    Rasburicase

    APIs // Active Pharmaceutical Ingredients

    DOSSIERs // Finished Dosage Forms

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    PharmaCompass

    Biopharma Group offers CDMO services with expertise in contract R&D for dried products & liquid formulations.

    Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

    2D Structure
    1. Also known as: 9002-12-4, Azane;[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate, Oxidase, urate, Uricase, candida utilis, Mfcd00082126, Ft-0686693
    Molecular Formula
    C18H26N5O14P
    Molecular Weight
    567.4  g/mol
    InChI Key
    VPXDHZMLJOJKOX-UHFFFAOYSA-N
    An enzyme that catalyzes the conversion of urate and unidentified products. It is a copper protein. The initial products decompose to form allantoin. EC 1.7.3.3.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    azane;[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate
    2.1.2 InChI
    InChI=1S/C18H23N4O14P.H3N/c23-5-7-14(13(28)16(34-7)22-4-2-10(25)20-18(22)30)36-37(31,32)33-6-8-11(26)12(27)15(35-8)21-3-1-9(24)19-17(21)29;/h1-4,7-8,11-16,23,26-28H,5-6H2,(H,31,32)(H,19,24,29)(H,20,25,30);1H3
    2.1.3 InChI Key
    VPXDHZMLJOJKOX-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=CC(=O)NC4=O)CO)O)O.N
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. Oxidase, Urate

    2. Urate Oxidase

    3. Uricase

    2.2.2 Depositor-Supplied Synonyms

    1. 9002-12-4

    2. Azane;[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] Hydrogen Phosphate

    3. Oxidase, Urate

    4. Uricase, Candida Utilis

    5. Mfcd00082126

    6. Ft-0686693

    7. Ft-0772402

    8. Uricase From Bacillus Fastidiosus, Lyophilized, ~9 U/mg

    9. Uricase From Arthrobacter Globiformis, Lyophilized Powder, 15-30 Units/mg Protein (biuret)

    10. Uricase From Candida Sp., Recombinant, Expressed In E. Coli, Lyophilized Powder, >=2 Units/mg Solid

    2.3 Create Date
    2007-02-09
    3 Chemical and Physical Properties
    Molecular Weight 567.4 g/mol
    Molecular Formula C18H26N5O14P
    Hydrogen Bond Donor Count8
    Hydrogen Bond Acceptor Count15
    Rotatable Bond Count8
    Exact Mass567.12138752 g/mol
    Monoisotopic Mass567.12138752 g/mol
    Topological Polar Surface Area255 Ų
    Heavy Atom Count38
    Formal Charge0
    Complexity1070
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count8
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
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