1. Posenacaftor [usan]
2. Bn5ut8i0t9
3. Pti-801
4. 2095064-05-2
5. Posenacaftor (usan)
6. Posenacaftor [inn]
7. Unii-bn5ut8i0t9
8. Posenacaftor [who-dd]
9. Chembl4594274
10. Schembl18736773
11. Glxc-25544
12. Who 11276
13. Hy-109187
14. Cs-0116460
15. D11683
16. (r)-8-methyl-2-(3-methylbenzofuran-2-yl)-5-(1-(tetrahydro-2h-pyran-4- Yl)ethoxy)quinoline-4-carboxylate
17. 4-quinolinecarboxylic Acid, 8-methyl-2-(3-methyl-2-benzofuranyl)-5-((1r)-1-(tetrahydro-2h-pyran-4-yl)ethoxy)
18. 4-quinolinecarboxylic Acid, 8-methyl-2-(3-methyl-2-benzofuranyl)-5-((1r)-1-(tetrahydro-2h-pyran-4-yl)ethoxy)-
19. 8-methyl-2-(3-methyl-1-benzofuran-2-yl)-5-[(1r)-1-(oxan-4-yl)ethoxy]quinoline-4-carboxylic Acid
20. 8-methyl-2-(3-methylbenzofuran-2-yl)-5-((1r)-1-(oxan-4-yl)ethoxy)quinoline-4-carboxylic Acid
| Molecular Weight | 445.5 g/mol |
|---|---|
| Molecular Formula | C27H27NO5 |
| XLogP3 | 5.5 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 5 |
| Exact Mass | 445.18892296 g/mol |
| Monoisotopic Mass | 445.18892296 g/mol |
| Topological Polar Surface Area | 81.8 Ų |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 681 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Investigated for use/treatment in addictions, osteoarthritis, and pain (acute or chronic).
PTI-801 is a novel form of oxycodone that minimizes the abuse and drug dependence that is often associated with oxycodone and other narcotic painkillers. The goal of developing PTI-801 is to ensure the safety of patients who have a legitimate medical need to treat severe chronic pain with a narcotic painkiller, and to protect the public from the consequences of abuse.
