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1. 3-(2-(4-(6-fluoro-3-(1,2-benzisoxazolyl))-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4h-pyrido(1,2-a)pyrimidin-4-one
2. 9 Hydroxy Risperidone
3. 9 Hydroxyrisperidone
4. 9 Oh Risperidone
5. 9-hydroxy-risperidone
6. 9-hydroxyrisperidone
7. 9-oh-risperidone
8. Invega
9. Invega Sustenna
10. Paliperidone
11. Palmitate, Paliperidone
12. R 76477
13. R-76477
14. R76477
15. Sustenna, Invega
1. 199739-10-1
2. Invega Sustenna
3. Xeplion
4. Invega Trinza
5. Ro92670
6. Ro 92670
7. Paliperidone Palmitate [usan]
8. R8p8usm8fr
9. 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4h-pyrido[1,2-a]pyrimidin-9-yl Palmitate
10. Jns010
11. Hexadecanoic Acid, 3-(2-(4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-2-methyl-4-oxo-4h-pyrido(1,2-a)pyrimidin-9-yl Ester
12. Chebi:83808
13. Jns-010
14. Ro-92670
15. R092670
16. (9rs)-3-(2-(4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4h-pyrido(1,2-a)pyrimidin-9-yl Hexadecanoate
17. 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4-oxo-6,7,8,9-tetrahydro-4h-pyrido[1,2-a]pyrimidin-9-yl Hexadecanoate
18. R-092670
19. Trinza
20. [3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-9-yl] Hexadecanoate
21. Hexadecanoic Acid, 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4h-pyrido[1,2-a]pyrimidin-9-yl Ester
22. Unii-r8p8usm8fr
23. 9-hydroxyrisperidone Palmitate
24. Jns 010
25. Pp3m
26. Paliperidone Janssen
27. Palperidone Palmitate
28. Paliperidone Palmitate-[d4]
29. Schembl1871384
30. Chembl2107360
31. Schembl12415674
32. Hy-a0019a
33. Dtxsid70870217
34. Paliperidone Palmitate [mi]
35. Bcp08473
36. Paliperidone Palmitate [jan]
37. Mfcd24386477
38. S5624
39. Paliperidone Palmitate [vandf]
40. Paliperidone Palmitate [mart.]
41. Paliperidone Palmitate [who-dd]
42. Sb17398
43. Ncgc00522023-01
44. Paliperidone Palmitate [ema Epar]
45. Ac-32485
46. As-77089
47. Paliperidone Palmitate [orange Book]
48. Cs-0016387
49. Ft-0673476
50. D83646
51. Q27157250
52. 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4h-pyrido[1,2-a]pyrimidin-9-ylpalmitate
53. 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-9-yl Hexadecanoate
| Molecular Weight | 664.9 g/mol |
|---|---|
| Molecular Formula | C39H57FN4O4 |
| XLogP3 | 10.1 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 20 |
| Exact Mass | 664.43638447 g/mol |
| Monoisotopic Mass | 664.43638447 g/mol |
| Topological Polar Surface Area | 88.2 Ų |
| Heavy Atom Count | 48 |
| Formal Charge | 0 |
| Complexity | 1090 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Xeplion is indicated for maintenance treatment of schizophrenia in adult patients stabilised with paliperidone or risperidone.
In selected adult patients with schizophrenia and previous responsiveness to oral paliperidone or risperidone, Xeplion may be used without prior stabilisation with oral treatment if psychotic symptoms are mild to moderate and a long-acting injectable treatment is needed.
Antipsychotic Agents
Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)
Dopamine D2 Receptor Antagonists
Compounds and drugs that bind to and inhibit or block the activation of DOPAMINE D2 RECEPTORS. (See all compounds classified as Dopamine D2 Receptor Antagonists.)
Serotonin 5-HT2 Receptor Antagonists
Drugs that bind to but do not activate SEROTONIN 5-HT2 RECEPTORS, thereby blocking the actions of SEROTONIN or SEROTONIN 5-HT2 RECEPTOR AGONISTS. Included under this heading are antagonists for one or more specific 5-HT2 receptor subtypes. (See all compounds classified as Serotonin 5-HT2 Receptor Antagonists.)
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