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    Technical details about MolPort-002-052-034, learn more about the structure, uses, toxicity, action, side effects and more

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    MolPort-002-052-034

    APIs // Active Pharmaceutical Ingredients

    PharmaCompass

    Phyton is a World Leader in Plant Cell Fermentation Technology and Commercial Manufacturing.

    Athena Pharmaceutiques is a Partner of Choice for Drug Delivery & Life Cycle Management.

    2D Structure
    1. Also known as: Clorgyline, 17780-72-2, Chlorgyline, Clorgilinum, Clorgilina, M and b 9302
    Molecular Formula
    C13H15Cl2NO
    Molecular Weight
    272.17  g/mol
    InChI Key
    BTFHLQRNAMSNLC-UHFFFAOYSA-N
    FDA UNII
    LYJ16FZU9Q
    An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    3-(2,4-dichlorophenoxy)-N-methyl-N-prop-2-ynylpropan-1-amine
    2.1.2 InChI
    InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3
    2.1.3 InChI Key
    BTFHLQRNAMSNLC-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CN(CCCOC1=C(C=C(C=C1)Cl)Cl)CC#C
    2.2 Other Identifiers
    2.2.1 UNII
    LYJ16FZU9Q
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Chlorgyline

    2. Clorgilin

    3. Clorgyline

    2.3.2 Depositor-Supplied Synonyms

    1. Clorgyline

    2. 17780-72-2

    3. Chlorgyline

    4. Clorgilinum

    5. Clorgilina

    6. M And B 9302

    7. Clorgiline [inn]

    8. M & B 9302

    9. N-methyl-n-propargyl-3-(2,4-dichlorophenoxy)propylamine

    10. N-(3-(2,4-dichlorophenoxy)propyl)-n-methyl-2-propynylamine

    11. M&b 9302

    12. Clorgiline (inn)

    13. Lyj16fzu9q

    14. N-(3-(2,4-dichlorophenoxy)propyl)-n-methylprop-2-yn-1-amine

    15. Chembl8706

    16. Chebi:3763

    17. N-[3-(2,4-dichlorophenoxy)propyl]-n-methylprop-2-yn-1-amine

    18. 2-propyn-1-amine, N-(3-(2,4-dichlorophenoxy)propyl)-n-methyl-

    19. 2-propynylamine, N-(3-(2,4-dichlorophenoxy)propyl)-n-methyl-

    20. Clorgilinum [inn-latin]

    21. Clorgilina [inn-spanish]

    22. 2-propyn-1-amine, N-(3-(2,4-dichlorophenoxy)propyl)-n-methyl- (9ci)

    23. Unii-lyj16fzu9q

    24. Cas-17780-75-5

    25. Brn 1976758

    26. 2-propyn-1-amine, N-[3-(2,4-dichlorophenoxy)propyl]-n-methyl-, Hydrochloride

    27. 3-(2,4-dichlorophenoxy)-n-methyl-n-prop-2-ynylpropan-1-amine

    28. Clorgiline [inn:ban]

    29. Prestwick0_000344

    30. Prestwick1_000344

    31. Prestwick2_000344

    32. Prestwick3_000344

    33. Lopac-m-3778

    34. Lopac0_000746

    35. Schembl61914

    36. Bspbio_000407

    37. Us8633208, Clorgyline

    38. Spbio_002328

    39. Bpbio1_000449

    40. Gtpl6636

    41. Dtxsid3048445

    42. Bdbm15581

    43. Zinc22200090

    44. Ccg-204831

    45. Db04017

    46. Sdccgsbi-0050724.p003

    47. Ncgc00015669-01

    48. Ncgc00015669-02

    49. Ncgc00015669-03

    50. Ncgc00015669-04

    51. Ncgc00015669-11

    52. Ncgc00162235-01

    53. M&b-9302

    54. Sbi-0050724.p002

    55. A20772

    56. D03248

    57. L001342

    58. Q2889652

    59. Brd-k73251053-003-03-2

    60. Brd-k73251053-003-13-1

    61. [3-(2,4-dichloro-phenoxy)-propyl]-methyl-prop-2-ynyl-amine

    62. [3-(2,4-dichlorophenoxy)propyl](methyl)prop-2-yn-1-ylamine

    63. N-[3-(2,4-dichlorophenoxy)propyl]-n-methyl-prop-2-yn-1-amine

    64. 3-(2,4-dichlorophenoxy)-n-methyl-n-prop-2-ynyl-propan-1-amine

    65. N-[(2,6-dichloro-4-methyl-3-pyridyl)carbonyl]-n-(3,4-dichlorophenyl)urea

    66. Clg

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 272.17 g/mol
    Molecular Formula C13H15Cl2NO
    XLogP34.2
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count6
    Exact Mass271.0530695 g/mol
    Monoisotopic Mass271.0530695 g/mol
    Topological Polar Surface Area12.5 Ų
    Heavy Atom Count17
    Formal Charge0
    Complexity263
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Antidepressive Agents

    Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)

    Monoamine Oxidase Inhibitors

    A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. (From Gilman, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p414) (See all compounds classified as Monoamine Oxidase Inhibitors.)

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