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1. Chemirosa, Cloretilo
2. Chloraethyl Dr. Henning
3. Chloride, Ethyl
4. Cloretilo Chemirosa
5. Ethyl Chloride
6. Gebauer Ethyl Chloride
7. Gebauer's Ethyl Chloride
8. Gebauers Ethyl Chloride
9. Wariactiv
1. Ethyl Chloride
2. 75-00-3
3. Ethane, Chloro-
4. Chlorene
5. Chelen
6. Monochloroethane
7. Anodynon
8. Chlorethyl
9. Cloretilo
10. Dublofix
11. Chloryl
12. Ether Chloratus
13. Ether Muriatic
14. Muriatic Ether
15. Aethylis Chloridum
16. Chloryl Anesthetic
17. Ether Hydrochloric
18. Hydrochloric Ether
19. Monochlorethane
20. Narcotile
21. Kelene
22. Aethylis
23. Chloridum
24. Aethylchlorid
25. Chloorethaan
26. Chloroaethan
27. Cloroetano
28. Etylu Chlorek
29. Cloruro Di Etile
30. C2h5cl
31. Chlorure D'ethyle
32. Chlorinated Ethanes
33. Nci-c06224
34. Ccris 3349
35. Hsdb 533
36. Ethane, Chloro Derivs.
37. Mono-chloroethane
38. Chloryle Anesthetic
39. Ai3-24474
40. Ethyl Chloride [usp]
41. 46u771erwk
42. 68411-72-3
43. Chebi:47554
44. Ethyl Chloride (usp)
45. Ether Chloridum
46. Chloorethaan [dutch]
47. Cloroetano [italian]
48. Chloroaethan [german]
49. Ethylchloride
50. Aethylchlorid [german]
51. Aethylchloride
52. Aethylchloride [german]
53. Etylu Chlorek [polish]
54. Mfcd00000961
55. Chlorure D'ethyle [french]
56. Cloruro Di Etile [italian]
57. Polychlorinated Ethanes
58. Gebauer's Ethyl Chloride
59. Einecs 200-830-5
60. Un1037
61. Chloranylethane
62. Unii-46u771erwk
63. Aetyl Chloride
64. Chloro-ethane
65. 1-chloroethane #
66. Chloroethane 99%
67. Einecs 270-142-8
68. Chlorinated Ethane Byproduct Residues
69. Ethyl Chloride (chloroethane)
70. Un 1037
71. Chloroethyl Group
72. 1-chloro-ethane
73. Chloroethane [iarc]
74. Ec 200-830-5
75. Chloroethane, >=98.0%
76. Chloroethane, >=99.7%
77. Chloroethane, >=99.8%
78. Ethyl Chloride [mi]
79. Chembl46058
80. Ethyl Chloride [hsdb]
81. Ethyl Chloride [vandf]
82. Ethane, Chloro- (8ci,9ci)
83. Ethyl Chloride [mart.]
84. Dtxsid1020302
85. Ethyl Chloride [who-dd]
86. Chloroethane, Purum, >=98.0%
87. Ethyl Chloride [usp Impurity]
88. Akos000261558
89. Db13259
90. Chloroethane 100 Microg/ml In Methanol
91. Ethyl Chloride [un1037] [flammable Gas]
92. F 160
93. Ft-0694900
94. R 160
95. C18248
96. D04088
97. A838306
98. Q409133
99. Chloroethane (ca. 15% In Tetrahydrofuran, Ca. 2.0mol/l)
100. Chloroethane Solution, 2.0 M In Diethyl Ether, Anhydrous
101. Chloroethane Solution, 1000 Mug/ml In Methanol, Analytical Standard
102. Chloroethane Solution, 2.0 M In Tert-butyl Methyl Ether, Anhydrous
103. Chloroethane Solution, 200 Mug/ml In Methanol, Analytical Standard
104. Chloroethane Solution, Certified Reference Material, Tracecert(r), 1000 Mug/ml In Methanol, Ampule Of 1 Ml
| Molecular Weight | 64.51 g/mol |
|---|---|
| Molecular Formula | C2H5Cl |
| XLogP3 | 1.2 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 0 |
| Rotatable Bond Count | 0 |
| Exact Mass | 64.0079779 g/mol |
| Monoisotopic Mass | 64.0079779 g/mol |
| Topological Polar Surface Area | 0 Ų |
| Heavy Atom Count | 3 |
| Formal Charge | 0 |
| Complexity | 2.8 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Anesthetics, Local
National Library of Medicine's Medical Subject Headings online file (MeSH, 1999)
Ethyl chloride is applied topically as a spray.
McEvoy, G.K. (ed.). AHFS Drug Information 90. Bethesda, MD: American Society of Hospital Pharmacists, Inc., 1990 (Plus Supplements 1990)., p. 2051
For use in local anesthesia ... /and/ used as a counterirritant ... .
McEvoy, G.K. (ed.). AHFS Drug Information 90. Bethesda, MD: American Society of Hospital Pharmacists, Inc., 1990 (Plus Supplements 1990)., p. 2051
MEDICATION (VET): Use of ethyl chloride ... restricted to the cat. ... May also be used to anesthetize birds. ... /Also/ for parakeets and canaries ... .
Booth, N.H., L.E. McDonald (eds.). Veterinary Pharmacology and Therapeutics. 5th ed. Ames, Iowa: Iowa State University Press, 1982., p. 196
For more Therapeutic Uses (Complete) data for ETHYL CHLORIDE (7 total), please visit the HSDB record page.
Because ethyl chloride is highly flammable, it should not be used in areas where ignition may occur. ... The drug should not be applied to broken skin or mucous membranes. During application of ethyl chloride, the skin adjacent to the area being treated should be covered with petrolatum to protect against tissue sloughing. ... Caution must be observed to avoid spilling the liquid on the skin. ... Deep general anesthesia followed by death has been reported. ... The patient should be observed for delayed nephrotoxicity or hepatotoxicity.
McEvoy, G.K. (ed.). AHFS Drug Information 90. Bethesda, MD: American Society of Hospital Pharmacists, Inc., 1990 (Plus Supplements 1990)., p. 2051
... The drug incr cardiac irritability and causes spontaneous arrhythmias. Asystole may occur before medullary paralysis. For this reason, the use of the drug by inhalation has been abandoned.
Haddad, L.M. and Winchester, J.F. Clinical Management of Poisoning and Drug Overdosage. Philadelphia, PA: W.B. Saunders Co., 1983., p. 768
Anesthetics, Local
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. (See all compounds classified as Anesthetics, Local.)
N - Nervous system
N01 - Anesthetics
N01B - Anesthetics, local
N01BX - Other local anesthetics
N01BX01 - Ethyl chloride
IT IS EASILY ABSORBED THROUGH MUCOUS MEMBRANES AND THE LUNG AND THROUGH THE SKIN. ETHYL CHLORIDE IS QUICKLY ELIMINATED FROM THE BODY; MOST OF THIS ELIMINATION OCCURS THROUGH THE LUNG.
American Conference of Governmental Industrial Hygienists. Documentation of the Threshold Limit Values for Substances in Workroom Air. Third Edition, 1971. Cincinnati, Ohio: American Conference of Governmental Industrial Hygienists, 1971. (Plus supplements to 1979), p. 107
The major portion of an inhaled dose is eliminated unchanged in exhaled breath, but minute traces may remain in the blood for some time ... . Some of the compound is also excreted in the urine, feces, and sweat.
USEPA; Summary Review of Health Effects Associated with Monochloroethane Health Issue Assessment. p 15 (1988) NTIS PB 88-236047
... Ethyl chloride is not metabolized to a significant degree.
Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 3483
... Dechlorination of a number of chloroethanes ... /was evaluated/ using hepatic microsome preparations from rats. ... For monochloroethane, enzymatic losses of chlorine amounted to less than 0.5 percent of the initial amount of radiolabel used. However, ... some dechlorination (not quantified) occurred in the absence of NADP, suggesting an alternate pathway of metabolism or a nonenzymatic breakdown of the compound.
USEPA; Summary Review of Health Effects Associated with Monochloroethane Health Issue Assessment. p 16 (1988) NTIS PB 88-236047
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