loader
Please Wait
Applying Filters...

Bora CDMO Bora CDMO

X
menu

    Market Place

    Market Place

    Post Enquiry

    Post Enquiry
    menu

    Technical details about MolPort-001-759-109, learn more about the structure, uses, toxicity, action, side effects and more

    Client Email Product
    Menu

    MolPort-001-759-109

    APIs // Active Pharmaceutical Ingredients

    PharmaCompass

    Phyton is a World Leader in Plant Cell Fermentation Technology and Commercial Manufacturing.

    Athena Pharmaceutiques is a Partner of Choice for Drug Delivery & Life Cycle Management.

    2D Structure
    1. Also known as: Ampa, 77521-29-0, (rs)-ampa, 74341-63-2, (r,s)-ampa, Ampa (pharmaceutical)
    Molecular Formula
    C7H10N2O4
    Molecular Weight
    186.17  g/mol
    InChI Key
    UUDAMDVQRQNNHZ-UHFFFAOYSA-N
    FDA UNII
    J090588E6X
    An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid
    2.1.2 InChI
    InChI=1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)
    2.1.3 InChI Key
    UUDAMDVQRQNNHZ-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1=C(C(=O)NO1)CC(C(=O)O)N
    2.2 Other Identifiers
    2.2.1 UNII
    J090588E6X
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Alpha Amino 3 Hydroxy 5 Methyl 4 Isoxazolepropionic Acid

    2. Ampa

    3. Ampa, (+-)-isomer

    4. Ampa, (r)-isomer

    5. Ampa, (r)-isomer, Monohydrobromide

    6. Ampa, (s)-isomer

    7. Ampa, (s)-isomer, Monohydrobromide

    2.3.2 Depositor-Supplied Synonyms

    1. Ampa

    2. 77521-29-0

    3. (rs)-ampa

    4. 74341-63-2

    5. (r,s)-ampa

    6. Ampa (pharmaceutical)

    7. Chembl13378

    8. Chebi:34018

    9. Alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic Acid

    10. J090588e6x

    11. L-ampa

    12. 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic Acid

    13. (+/-)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

    14. 2-amino-3-(5-methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic Acid

    15. 2-amino-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic Acid

    16. (r,s)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

    17. C7h10n2o4

    18. 4-isoxazolepropanoic Acid, A-amino-2,3-dihydro-5-methyl-3-oxo-

    19. Gnf-pf-2579

    20. Unii-j090588e6x

    21. 4-isoxazolepropanoic Acid, Alpha-amino-2,3-dihydro-5-methyl-3-oxo-

    22. Gamma-amino-3-hydroxy-5-methylisoxazole-4-propionic Acid

    23. Dl-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic Acid

    24. (+-)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

    25. Alpha-amino-2,3-dihydro-5-methyl-3-oxoisoxazolepropionic Acid

    26. D,l-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic Acid

    27. Ampa [mi]

    28. [3h]ampa

    29. (r,s) Ampa

    30. Ampa, D,l-

    31. Lopac0_000581

    32. Schembl68799

    33. Gtpl4077

    34. Gtpl4131

    35. Dtxsid20868301

    36. 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic Acid

    37. Hms3266a13

    38. Hms3411a07

    39. Hms3675a07

    40. Zca34163

    41. 4-isoxazolepropanoic Acid, .alpha.-amino-2,3-dihydro-5-methyl-3-oxo-

    42. Bdbm50002370

    43. Mfcd00069214

    44. Pdsp1_001835

    45. Pdsp2_001818

    46. Akos017343917

    47. Ab02804

    48. Ccg-204670

    49. Hy-100815b

    50. Sb38931

    51. Sb38934

    52. Sdccgsbi-0050563.p002

    53. Ncgc00015458-04

    54. Ncgc00015458-05

    55. Ncgc00024481-03

    56. Da-02875

    57. Db-016844

    58. Cs-0021074

    59. Ft-0661849

    60. Ft-0762346

    61. Ft-0772278

    62. M01253

    63. L000026

    64. Sr-01000075447-3

    65. Q66370552

    66. ( )-a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

    67. (rs)-?-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

    68. (rs)-a-amino-3-hydroxy-5-methylisoxazole-4-propanoic Acid

    69. 2-amino-3-(5-methyl-3-oxo-isoxazol-4-yl)propanoic Acid

    70. 2-ammonio-3-(3-hydroxy-5-methylisoxazol-4-yl)propanoate

    71. (r,s)-

    72. A-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

    73. (rs)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

    74. 2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)-propionic Acid

    75. 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic Acid.

    76. (r,s)-a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

    77. (r,s)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-propionic Acid

    78. (rs)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)-propionicacid

    79. .alpha.-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic Acid

    80. .gamma.-amino-3-hydroxy-5-methylisoxazole-4-propionic Acid

    81. 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propanoic Acid

    82. (+/-)-.alpha.-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

    83. 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic Acid(dl-ampa)

    84. Dl-.alpha.-amino-3-hydroxy-5-methylisoxazole-4-propionic Acid

    85. 110592-37-5

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 186.17 g/mol
    Molecular Formula C7H10N2O4
    XLogP3-3.2
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count3
    Exact Mass186.06405680 g/mol
    Monoisotopic Mass186.06405680 g/mol
    Topological Polar Surface Area102 Ų
    Heavy Atom Count13
    Formal Charge0
    Complexity284
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Excitatory Amino Acid Agonists

    Drugs that bind to and activate excitatory amino acid receptors. (See all compounds classified as Excitatory Amino Acid Agonists.)

    Post Enquiry
    POST ENQUIRY