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Technical details about Milbemycin Oxime, learn more about the structure, uses, toxicity, action, side effects and more

Milbemycin Oxime

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

13 Suppliers, 5 CEP/COS, 1 EU WC, 6 NDC API, 10 Listed Suppliers

DEVELOPMENTS

2 Drug(s) in Development

2 Drug(s) in Development

PRICE INFORMATION

API Reference Price, API Exports, API Imports, FDF Imports

DOSSIERs // Finished Dosage Forms

24 Dossiers, 21 Canada, 3 Listed Dossiers

RELATED EXCIPIENT COMPANIES

Suppliers, 19 Kerry, 14 Roquette, 10 Sigachi Industries, 9 Microlex e.U, 8 Gangwal Healthcare, 6 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 5 Actylis, 5 DFE Pharma, 5 Gangwal Chemicals, 4 SPI Pharma, 4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 3 Ingredion Pharma Solutions, 3 Prachin Chemical, 3 Nanjing Well Pharmaceutical, 3 Vasa Pharmachem, 1 Pfanstiehl, 1 BASF, 1 Pharmatrans-Sanaq, 1 Pharm-RX Chemical, 1 Finar, 1 DKSH, 1 Ideal Cures Pvt Ltd, 1 Minakem, 1 Jai Radhe Sales, 1 Seppic

EXCIPIENTS BY APPLICATIONS

48 Fillers, Diluents & Binders, 20 Direct Compression, 18 Disintegrants & Superdisintegrants, 14 Thickeners and Stabilizers, 11 Lubricants & Glidants, 11 Granulation, 10 Co-Processed Excipients, 8 Taste Masking, 7 Coating Systems & Additives, 7 Parenteral, 6 Controlled & Modified Release, 5 Chewable & Orodispersible Aids, 3 Film Formers & Plasticizers, 3 API Stability Enhancers, 2 Topical, 2 Rheology Modifiers, 2 Emulsifying Agents, 1 Solubilizers

MARKET PLACE

8 APIs

8 APIs

PATENTS

5 Health Canada Patents

5 Health Canada Patents

ANALYTICAL SOLUTION(s)

1 EDQM Standards, 1 USP Standards, 1 Other Ref. Standards

DIGITAL CONTENT

1 News

1 News

Milbemycin Oxime
Chemistry
Full Screen View

1. Also known as: Milbemycin a, 5-oxime, Unii-0502pun0gt, Cga-179246, Schembl120526, 0502pun0gt, Hy-b0778

Molecular Formula

C₆₃H₈₈N₂O₁₄

Molecular Weight

1097.4 g/mol

InChI Key

CKVMAPHTVCTEMM-ALPQRHTBSA-N

1 2D Structure

2D Structure

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(1R,4S,5'S,6R,6'R,8R,10E,13R,14E,16E,20R,21Z,24S)-6'-ethyl-24-hydroxy-21-hydroxyimino-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one;(1R,4S,5'S,6R,6'R,8R,10E,13R,14E,16E,20R,21Z,24S)-24-hydroxy-21-hydroxyimino-5',6',11,13,22-pentamethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one

2.1.2 InChI

InChI=1S/C32H45NO7.C31H43NO7/c1-6-27-21(4)12-13-31(40-27)17-25-16-24(39-31)11-10-20(3)14-19(2)8-7-9-23-18-37-29-28(33-36)22(5)15-26(30(34)38-25)32(23,29)35;1-18-7-6-8-23-17-36-28-27(32-35)21(4)14-26(31(23,28)34)29(33)37-25-15-24(10-9-19(2)13-18)39-30(16-25)12-11-20(3)22(5)38-30/h7-10,15,19,21,24-27,29,35-36H,6,11-14,16-18H2,1-5H3;6-9,14,18,20,22,24-26,28,34-35H,10-13,15-17H2,1-5H3/b8-7+,20-10+,23-9+,33-28-;7-6+,19-9+,23-8+,32-27-/t19-,21-,24+,25-,26-,27+,29+,31+,32+;18-,20-,22+,24+,25-,26-,28+,30-,31+/m00/s1

2.1.3 InChI Key

CKVMAPHTVCTEMM-ALPQRHTBSA-N

2.1.4 Canonical SMILES

CCC1C(CCC2(O1)CC3CC(O2)CC=C(CC(C=CC=C4COC5C4(C(C=C(C5=NO)C)C(=O)O3)O)C)C)C.CC1CCC2(CC3CC(O2)CC=C(CC(C=CC=C4COC5C4(C(C=C(C5=NO)C)C(=O)O3)O)C)C)OC1C

2.1.5 Isomeric SMILES

CC[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/C[C@H](/C=C/C=C/4\CO[C@H]\5[C@@]4([C@@H](C=C(/C5=N/O)C)C(=O)O3)O)C)\C)C.C[C@H]1CC[C@]2(C[C@@H]3C[C@H](O2)C/C=C(/C[C@H](/C=C/C=C/4\CO[C@H]\5[C@@]4([C@@H](C=C(/C5=N/O)C)C(=O)O3)O)C)\C)O[C@@H]1C

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Interceptor

2. Milbe Mite

3. Milbemycin A, 5-oxime

4. Milbemycin Oxime

2.2.2 Depositor-Supplied Synonyms

1. Milbemycin A, 5-oxime

2. Unii-0502pun0gt

3. Cga-179246

4. Schembl120526

5. 0502pun0gt

6. Hy-b0778

2.3 Create Date

2007-12-05

3 Chemical and Physical Properties

Molecular Formula	C₆₃H₈₈N₂O₁₄
Molecular Weight	1097.4 g/mol
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	16
Rotatable Bond Count	1
Exact Mass	1096.62355549 g/mol
Monoisotopic Mass	1096.62355549 g/mol
Topological Polar Surface Area	214 Å²
Heavy Atom Count	79
Formal Charge	0
Complexity	2260
Isotope Atom Count	0
Defined Atom Stereocenter Count	18
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	8
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anthelmintics

Agents that kill parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal. (See all compounds classified as Anthelmintics.)

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