Please Wait
Applying Filters...
menu
    • menu
    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    Virtual Booth

    Contact Supplier

    Cohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

    Virtual Booth

    Contact Supplier

    Rusan Pharma: Over 30 years of specializing in the treatment of Addiction and Pain Management.

    Virtual Booth

    Contact Supplier

    Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

    Virtual Booth

    Contact Supplier

    Fishfa Biogenics: Renowned Manufacturer, & Exporter of Tacrolimus & Mupirocin API.

    Virtual Booth

    Contact Supplier

    pharmacompass-2-m-2025-11-03

    Virtual Booth

    An Enquiry

    Menu

    Luvadaxistat

    DEVELOPMENTS

    DIGITAL CONTENT

    PharmaCompass
    Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: Luvadaxistat [usan], Tak-831, 76ic00yrvr, Tak831, Chembl2338801, 4-hydroxy-6-{2-[4-(trifluoromethyl)phenyl]ethyl}pyridazin-3(2h)-one
    Molecular Formula
    C13H11F3N2O2
    Molecular Weight
    284.23  g/mol
    InChI Key
    QBQMUMMSYHUDFM-UHFFFAOYSA-N
    FDA UNII
    76IC00YRVR
    TAK-831 is under investigation in clinical trial NCT03214588 (Efficacy, Tolerability, and Pharmacokinetics of Multiple Doses of Oral TAK-831 in Adults With Friedreich Ataxia).
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    6-[2-[4-(trifluoromethyl)phenyl]ethyl]-1,2-dihydropyridazine-3,4-dione
    2.1.2 InChI
    InChI=1S/C13H11F3N2O2/c14-13(15,16)9-4-1-8(2-5-9)3-6-10-7-11(19)12(20)18-17-10/h1-2,4-5,7H,3,6H2,(H,17,19)(H,18,20)
    2.1.3 InChI Key
    QBQMUMMSYHUDFM-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=CC(=CC=C1CCC2=CC(=O)C(=O)NN2)C(F)(F)F
    2.2 Other Identifiers
    2.2.1 UNII
    76IC00YRVR
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. Luvadaxistat [usan]

    2. Tak-831

    3. 76ic00yrvr

    4. Tak831

    5. Chembl2338801

    6. 4-hydroxy-6-{2-[4-(trifluoromethyl)phenyl]ethyl}pyridazin-3(2h)-one

    7. 1425511-32-5

    8. 4-hydroxy-6-(2-(4-(trifluoromethyl)phenyl)ethyl)pyridazin-3(2h)-one

    9. 3(2h)-pyridazinone, 4-hydroxy-6-(2-(4-(trifluoromethyl)phenyl)ethyl)-

    10. Luvadaxistat [inn]

    11. Unii-76ic00yrvr

    12. Luvadaxistat [who-dd]

    13. Luvadaxistat; Tak-831

    14. Schembl14719667

    15. Bdbm50431085

    16. Who 11254

    17. Zinc95592350

    18. At32834

    19. Hy-109183

    20. Cs-0116454

    21. 4-hydroxy-6-(2-(4-(trifluoromethyl)phenyl)ethyl)-2,3-dihydropyridazin-3-one

    2.4 Create Date
    2013-03-21
    3 Chemical and Physical Properties
    Molecular Weight 284.23 g/mol
    Molecular Formula C13H11F3N2O2
    XLogP32.7
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count3
    Exact Mass284.07726208 g/mol
    Monoisotopic Mass284.07726208 g/mol
    Topological Polar Surface Area58.2 Ų
    Heavy Atom Count20
    Formal Charge0
    Complexity424
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1