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    Technical details about Lorcainide, learn more about the structure, uses, toxicity, action, side effects and more

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    Lorcainide

    APIs // Active Pharmaceutical Ingredients

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    Veranova: A CDMO that manages complexity with confidence.

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    2D Structure
    1. Also known as: Lopantrol, Socainide hydrochloride, Isocainide hydrochloride, Lorcainide hydrochloride [usan], Einecs 261-504-6, N-(4-chlorophenyl)-2-phenyl-n-(1-propan-2-ylpiperidin-1-ium-4-yl)acetamide;chloride
    Molecular Formula
    C22H28Cl2N2O
    Molecular Weight
    407.4  g/mol
    InChI Key
    FSFSWNBDCJVFGI-UHFFFAOYSA-N
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N-(4-chlorophenyl)-2-phenyl-N-(1-propan-2-ylpiperidin-1-ium-4-yl)acetamide;chloride
    2.1.2 InChI
    InChI=1S/C22H27ClN2O.ClH/c1-17(2)24-14-12-21(13-15-24)25(20-10-8-19(23)9-11-20)22(26)16-18-6-4-3-5-7-18;/h3-11,17,21H,12-16H2,1-2H3;1H
    2.1.3 InChI Key
    FSFSWNBDCJVFGI-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(C)[NH+]1CCC(CC1)N(C2=CC=C(C=C2)Cl)C(=O)CC3=CC=CC=C3.[Cl-]
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. 4'-chloro-n-(1-isopropyl-4-piperidyl)-2-phenylacetanilide

    2. Lorcainid

    3. Lorcainide

    4. Lorcainide Monohydrochloride

    5. R 15889

    6. R15889

    7. Ro 13-1042

    2.2.2 Depositor-Supplied Synonyms

    1. Lopantrol

    2. Socainide Hydrochloride

    3. Isocainide Hydrochloride

    4. Lorcainide Hydrochloride [usan]

    5. Einecs 261-504-6

    6. N-(4-chlorophenyl)-2-phenyl-n-(1-propan-2-ylpiperidin-1-ium-4-yl)acetamide;chloride

    7. Ro 13-1042

    8. Lorivox

    9. R 15889

    10. 1t1s98onm1

    11. 1313498-17-7

    12. Benzeneacetamide, N-(4-chlorophenyl)-n-(1-(1-methylethyl)-4-piperidinyl)-, Monohydrochloride

    13. Lorcainida Clorhidrato [spanish]

    14. Lorcainida Clorhidrato

    15. Unii-1t1s98onm1

    16. N-(p-chlorophenyl)-n-(1-isopropylpiperidin-4-yl)phenylacetamide Hydrochloride

    17. Nsc 310411

    2.3 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 407.4 g/mol
    Molecular Formula C22H28Cl2N2O
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count5
    Exact Mass406.1578689 g/mol
    Monoisotopic Mass406.1578689 g/mol
    Topological Polar Surface Area24.8 Ų
    Heavy Atom Count27
    Formal Charge0
    Complexity433
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Arrhythmia Agents

    Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)

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