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    Technical details about Levalbuterol, learn more about the structure, uses, toxicity, action, side effects and more

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    Levalbuterol

    APIs // Active Pharmaceutical Ingredients

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    2D Structure
    Also known as: 50293-90-8, Levalbuterol hcl, Xopenex, (r)-albuterol hydrochloride, Levosalbutamol hydrochloride, R-albuterol hydrochloride
    Molecular Formula
    C13H22ClNO3
    Molecular Weight
    275.77  g/mol
    InChI Key
    OWNWYCOLFIFTLK-YDALLXLXSA-N
    FDA UNII
    WDQ1526QJM
    The R-isomer of albuterol.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol;hydrochloride
    2.1.2 InChI
    InChI=1S/C13H21NO3.ClH/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;/h4-6,12,14-17H,7-8H2,1-3H3;1H/t12-;/m0./s1
    2.1.3 InChI Key
    OWNWYCOLFIFTLK-YDALLXLXSA-N
    2.1.4 Canonical SMILES
    CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.Cl
    2.1.5 Isomeric SMILES
    CC(C)(C)NC[C@@H](C1=CC(=C(C=C1)O)CO)O.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    WDQ1526QJM
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Hydrochloride, Levalbuterol

    2. Hydrochloride, Levosalbutamol

    3. Levalbuterol

    4. Levosalbutamol Hydrochloride

    5. Xopenex

    2.3.2 Depositor-Supplied Synonyms

    1. 50293-90-8

    2. Levalbuterol Hcl

    3. Xopenex

    4. (r)-albuterol Hydrochloride

    5. Levosalbutamol Hydrochloride

    6. R-albuterol Hydrochloride

    7. (r)-salbutamol Hydrochloride

    8. Levalbuterol Hydrochloride [usan:usp]

    9. Nsc-759255

    10. Albuterol Hydrochloride, R-

    11. Wdq1526qjm

    12. (r)-4-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol Hydrochloride

    13. (r)-albuterol

    14. 50293-90-8(hcl)

    15. 148563-16-0

    16. Alfa1-[[1,1-dimethylethylamino]methyl]-4-hydroxy-1-(s),3-benzene Dimethanol Hydrochlorid

    17. (-)-salbutamol Hydrochloride

    18. Zopenex

    19. Levalbuterol Hydrochloride [usan]

    20. Unii-wdq1526qjm

    21. (r)-4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol Hydrochloride

    22. Xopenex (tn)

    23. Zopenex [common Misspelling Of Xopenex]

    24. Salbutamol (hydrochloride)

    25. Schembl40682

    26. Chembl1201061

    27. Albuterol (r)-form Hydrochloride

    28. Levalbuterol Hydrochloride (usp)

    29. Dtxsid20198296

    30. Pharmakon1600-01505811

    31. Bcp04477

    32. Ccg-39986

    33. Mfcd08067728

    34. Nsc759255

    35. Akos015961919

    36. (r)-salbutamol ((r)-albuterol Hcl)

    37. Bs-1006

    38. Nsc 759255

    39. (r)-alpha(sup 1)-((tert-butylamino)methyl)-4-hydroxy-m-xylene-alpha,alpha'-diol Hydrochloride

    40. 4-[(1r)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol Hydrochloride

    41. 1,3-benzenedimethanol, Alpha1-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-, Hydrochloride, (alpha1r)-

    42. 2-(hydroxymethyl)-4-{(1r)-1-hydroxy-2-[(2-methyl-2-propanyl)amino ]ethyl}phenol Hydrochloride (1:1)

    43. Ac-23919

    44. Levalbuterol Hydrochloride [usp-rs]

    45. Levalbuterol Hydrochloride, >=98% (hplc)

    46. Levosalbutamol Hydrochloride [mart.]

    47. Levosalbutamol Hydrochloride [who-dd]

    48. Albuterol (r)-form Hydrochloride [mi]

    49. D02281

    50. Levalbuterol Hydrochloride [orange Book]

    51. 293l908

    52. A928075

    53. Levalbuterol Hydrochloride [usp Monograph]

    54. Q27292577

    55. 4-[(1r)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol;hydrochloride

    56. Alfa1-[[1,1-dimethylethylamino]methyl]-4-hydroxy-1-(s),3-benzenedimethanolhydrochlorid

    57. Levalbuterol Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    58. (r)-.alpha.(sup 1)-((tert-butylamino)methyl)-4-hydroxy-m-xylene-.alpha.,.alpha.'-diol Hydrochloride

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 275.77 g/mol
    Molecular Formula C13H22ClNO3
    Hydrogen Bond Donor Count5
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count5
    Exact Mass275.1288213 g/mol
    Monoisotopic Mass275.1288213 g/mol
    Topological Polar Surface Area72.7 Ų
    Heavy Atom Count18
    Formal Charge0
    Complexity227
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameLevalbuterol hydrochloride
    Drug LabelXopenex (levalbuterol HCl) Inhalation Solution is a sterile, clear, colorless, preservative-free solution of the hydrochloride salt of levalbuterol, the (R)-enantiomer of the drug substance racemic albuterol. Levalbuterol HCl is a relatively selectiv...
    Active IngredientLevalbuterol hydrochloride
    Dosage FormSolution
    RouteInhalation
    Strengtheq 0.021% base; eq 0.25% base; eq 0.0103% base; eq 0.042% base
    Market StatusPrescription
    CompanyTeva Parenteral; Teva Pharms Usa; Mylan Speclt; Cipla; Watson Labs

    2 of 2  
    Drug NameLevalbuterol hydrochloride
    Drug LabelXopenex (levalbuterol HCl) Inhalation Solution is a sterile, clear, colorless, preservative-free solution of the hydrochloride salt of levalbuterol, the (R)-enantiomer of the drug substance racemic albuterol. Levalbuterol HCl is a relatively selectiv...
    Active IngredientLevalbuterol hydrochloride
    Dosage FormSolution
    RouteInhalation
    Strengtheq 0.021% base; eq 0.25% base; eq 0.0103% base; eq 0.042% base
    Market StatusPrescription
    CompanyTeva Parenteral; Teva Pharms Usa; Mylan Speclt; Cipla; Watson Labs

    5 Pharmacology and Biochemistry
    5.1 FDA Pharmacological Classification
    5.1.1 Pharmacological Classes
    beta2-Adrenergic Agonist [EPC]; Adrenergic beta2-Agonists [MoA]
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