Please Wait
Applying Filters...
menu
    • menu
    Coral

    Virtual Booth

    Contact Supplier

    China’s top API & intermediate manufacturer, delivering advanced CMO/CDMO solutions to 60+ countries, empowering global health progress

    Virtual Booth

    Contact Supplier

    AMI Lifesciences is Driven by Chemistry. Powered by People.

    Virtual Booth

    Contact Supplier

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    Virtual Booth

    Contact Supplier

    Alchem offers Botanical APIs for Pharmaceuticals, Cosmetics and Nutraceuticals// FDA-inspected and EU-GMP certified.

    Virtual Booth

    Contact Supplier

    pharmacompass-2-m-2026-04-20

    Virtual Booth

    An Enquiry

    Menu

    Iopofosine i 131

    DEVELOPMENTS

    PharmaCompass
    Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: Nm-404 i-131, 873438-88-1, 131i-nm-404, Clr 131, Clr-131, I-131-clr1404
    Molecular Formula
    C29H53INO4P
    Molecular Weight
    641.6  g/mol
    InChI Key
    ZOAIEFWMQLYMTF-YRKXUXMHSA-N
    FDA UNII
    R048696O9L
    Iodine I 131 Iopofosine is a radioconjugate composed of iopofosine, a phospholipid ether analog, labeled with the radioactive isotope iodine I 131, with potential antineoplastic activity. Upon administration, iodine I 131 iopofosine selectively accumulates in and retains within tumor cells for a prolonged period of time due to the decreased activity of a phospholipase D (PLD) in tumor cells compared to normal cells, thereby delivering cytotoxic radiation specifically to tumor cells. PLD is an enzyme found in the cell membrane of normal cells that degrades phospholipids.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    18-(4-iodophenyl)octadecyl 2-(trimethylazaniumyl)ethyl phosphate
    2.1.2 InChI
    InChI=1S/C29H53INO4P/c1-31(2,3)25-27-35-36(32,33)34-26-19-17-15-13-11-9-7-5-4-6-8-10-12-14-16-18-20-28-21-23-29(30)24-22-28/h21-24H,4-20,25-27H2,1-3H3/i30+4
    2.1.3 InChI Key
    ZOAIEFWMQLYMTF-YRKXUXMHSA-N
    2.2 Other Identifiers
    2.2.1 UNII
    R048696O9L
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 131i-clr1404

    2.3.2 Depositor-Supplied Synonyms

    1. Nm-404 I-131

    2. 873438-88-1

    3. 131i-nm-404

    4. Clr 131

    5. Clr-131

    6. I-131-clr1404

    7. Iopofosine (131i)

    8. R048696o9l

    9. Iopofosine I 131

    10. Clr131

    11. Ethanaminium, 2-((hydroxy((18-(4-(iodo-131i)phenyl)octadecyl)oxy)phosphinyl)oxy)-n,n,n-trimethyl-, Inner Salt

    12. 131i-clr1404

    13. Clr-1404 I-131

    14. 131i-nm404

    15. 18-(p-(131i)-iodophenyl)octadecyl Phosphocholine

    16. 2-((hydroxy((18-(4-(131i)iodophenyl)octadecyl)oxy)phosphinyl)oxy)-n,n,ntrimethylethanaminium Inner Salt

    17. Refchem:201259

    18. Iodine I 131 Iopofosine

    19. Pdc Clr 131

    20. I-131 Ple Analogue Clr1404

    21. (131i)-clr1404

    22. Clr 1404 I-131

    23. ((131)i)nm404

    24. Phospholipid Ether-drug Conjugate Clr 131

    25. 18-(4-(131i)iodophenyl)octadecyl 2-(trimethylazaniumyl)ethyl Phosphate

    26. Iopofosine I 131 [usan]

    27. Unii-r048696o9l

    28. 131i-nm 404

    29. 18-(p-(i-131)-iodophenyl)octadecyl Phosphocholine

    30. Who 11916

    31. 18-(4-(131i)iodanylphenyl)octadecyl 2-(trimethylazaniumyl)ethyl Phosphate

    32. Iopofosine I 131 (usan)

    33. Iopofosina I 131

    34. Orb1700833

    35. Chembl4297495

    36. Schembl29460687

    37. Zoaiefwmqlymtf-yrkxuxmhsa-n

    38. Iopofosine (131 I) [who-dd]

    39. Akos040748156

    40. Db15244

    41. Iopofosine ((1)(3)(1)i) [inn]

    42. D12224

    43. T27048

    44. Q27287590

    45. 18-(p-(131i )-iodophenyl)octadecyl Phosphocholine

    2.4 Create Date
    2007-04-30
    3 Chemical and Physical Properties
    Molecular Weight 641.6 g/mol
    Molecular Formula C29H53INO4P
    XLogP39.9
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count24
    Exact Mass Da
    Monoisotopic Mass Da
    Topological Polar Surface Area58.6
    Heavy Atom Count36
    Formal Charge0
    Complexity542
    Isotope Atom Count1
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    • Privacy policy
    • Terms and conditions
    • Disclaimers
    • LinkedIn
    • Product listings are provided for informational purposes only. We do not supply or sell any products. Any products that may be covered by patent(s) are supplied solely for uses permitted under Section 107A of the Indian Patents Act and not for commercial sale.