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    Hydronidone

    DEVELOPMENTS

    DIGITAL CONTENT

    PharmaCompass
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    2D Structure
    Also known as: Hydronidone, 851518-71-3, F 351, F-351, N-(4-hydroxyphenyl)-5-methyl-2-1h-pyridone, N-(4-hydroxyphenyl)-5-methyl-2-pyridone
    Molecular Formula
    C12H11NO2
    Molecular Weight
    201.22  g/mol
    InChI Key
    NETTXQJYJRFTFS-UHFFFAOYSA-N
    FDA UNII
    RXQ128313W
    Hydronidone has antifibrotic activity.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    1-(4-hydroxyphenyl)-5-methylpyridin-2-one
    2.1.2 InChI
    InChI=1S/C12H11NO2/c1-9-2-7-12(15)13(8-9)10-3-5-11(14)6-4-10/h2-8,14H,1H3
    2.1.3 InChI Key
    NETTXQJYJRFTFS-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1=CN(C(=O)C=C1)C2=CC=C(C=C2)O
    2.2 Other Identifiers
    2.2.1 UNII
    RXQ128313W
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Hydronidone

    2. N-(4-hydroxyphenyl)-5-methyl-2-pyridone

    2.3.2 Depositor-Supplied Synonyms

    1. Hydronidone

    2. 851518-71-3

    3. F 351

    4. F-351

    5. N-(4-hydroxyphenyl)-5-methyl-2-1h-pyridone

    6. N-(4-hydroxyphenyl)-5-methyl-2-pyridone

    7. Rxq128313w

    8. F-351;f351

    9. 1-(4-hydroxyphenyl)-5-methyl-1h-pyridine-2-one

    10. Schembl143564

    11. Unii-rxq128313w

    12. 1-(4-hydroxyphenyl)-5-methylpyridin-2-one

    13. Chembl4297288

    14. Dtxsid40459058

    15. Zinc21981322

    16. Akos016006473

    17. Db06299

    18. Sb18945

    19. F351

    20. Db-115847

    21. Hy-100438

    22. Cs-0019024

    23. Ft-0669968

    24. Ft-0669969

    25. Q27288328

    2.4 Create Date
    2006-10-26
    3 Chemical and Physical Properties
    Molecular Weight 201.22 g/mol
    Molecular Formula C12H11NO2
    XLogP31.5
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count1
    Exact Mass201.078978594 g/mol
    Monoisotopic Mass201.078978594 g/mol
    Topological Polar Surface Area40.5 Ų
    Heavy Atom Count15
    Formal Charge0
    Complexity312
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Indication

    Investigated for use/treatment in liver disease.