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    Technical details about DSSTox_CID_3603, learn more about the structure, uses, toxicity, action, side effects and more

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    DSSTox_CID_3603

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    2D Structure
    Also known as: 71-27-2, Suxamethonium chloride, Succinyldicholine chloride, Anectine, Suxamethonii chloridum, Lysthenon
    Molecular Formula
    C14H30Cl2N2O4
    Molecular Weight
    361.3  g/mol
    InChI Key
    YOEWQQVKRJEPAE-UHFFFAOYSA-L
    FDA UNII
    I9L0DDD30I
    A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]azanium;dichloride
    2.1.2 InChI
    InChI=1S/C14H30N2O4.2ClH/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2
    2.1.3 InChI Key
    YOEWQQVKRJEPAE-UHFFFAOYSA-L
    2.1.4 Canonical SMILES
    C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C.[Cl-].[Cl-]
    2.2 Other Identifiers
    2.2.1 UNII
    I9L0DDD30I
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Anectine

    2. Bromide, Suxamethonium

    3. Celocurine

    4. Dibromide, Succinylcholine

    5. Dichloride, Succinylcholine

    6. Dicholine Succinate

    7. Diiodide, Succinylcholine

    8. Diperchlorate, Succinylcholine

    9. Ditilin

    10. Listenon

    11. Lysthenon

    12. Myorelaxin

    13. Quelicin

    14. Succicuran

    15. Succinate, Dicholine

    16. Succinylcholine

    17. Succinylcholine Dibromide

    18. Succinylcholine Dichloride

    19. Succinylcholine Dichloride, Di H2o

    20. Succinylcholine Dichloride, Di-h2o

    21. Succinylcholine Diiodide

    22. Succinylcholine Diperchlorate

    23. Succinylcholine Iodide

    24. Succinyldicholine

    25. Suxamethonium

    26. Suxamethonium Bromide

    27. Suxamethonium Chloride

    2.3.2 Depositor-Supplied Synonyms

    1. 71-27-2

    2. Suxamethonium Chloride

    3. Succinyldicholine Chloride

    4. Anectine

    5. Suxamethonii Chloridum

    6. Lysthenon

    7. Midarine

    8. Quelicin

    9. Scoline

    10. Pantolax

    11. Suxamethonium Dichloride

    12. Chlorsuccinylcholin

    13. Succinylcholine Dichloride

    14. Succinylforte

    15. Lysthenone

    16. Succicuran

    17. Sucostrin

    18. Suxcert

    19. Suxinyl

    20. Bis(succinyldichlorocholine)

    21. Choline Chloride Succinate (2:1)

    22. Succinyl-asta

    23. Scoline Chloride

    24. Cloruro De Suxametonio

    25. Anectine Chloride

    26. Quelicin Chloride

    27. Sucostrin Chloride

    28. Chlorure De Succinilcoline

    29. 2-dimethylaminoethyl Succinate Dimethochloride

    30. Suxamethionium Chloride

    31. Listenon

    32. Succinoylcholine Chloride

    33. Choline, Chloride Succinate

    34. Choline Succinate Dichloride

    35. Succinyl Bischoline Chloride

    36. Succinylbischoline Dichloride

    37. (2-hydroxyethyl)trimethylammonium Chloride Succinate

    38. I9l0ddd30i

    39. Bis(2-dimethylaminoethyl)succinate Bis(methochloride)

    40. Suxamethonium Chloride [inn]

    41. Chebi:61219

    42. Nsc-49132

    43. Succinic Acid, Diester With Choline Chloride

    44. Ncgc00094357-01

    45. Myoplegine

    46. Sukolin

    47. Succin

    48. Dsstox_cid_3603

    49. Diacetylcholine Dichloride

    50. Dsstox_rid_77103

    51. Ethanaminium, 2,2'-((1,4-dioxo-1,4-butanediyl)bis(oxy))bis(n,n,n-trimethyl-), Dichloride

    52. Trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]azanium;dichloride

    53. Dsstox_gsid_23603

    54. Suxamethonium Chloride (inn)

    55. Succinyldicholine Dichloride

    56. Succamethonium Chloratum

    57. Quelicin Preservative Free

    58. 2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(n,n,n-trimethylethanaminium) Dichloride

    59. Cas-71-27-2

    60. Chlorsuccinylcholin [german]

    61. Sukcinylcholinchlorid [czech]

    62. Sukcinylcholinchlorid

    63. Succinilcolina Cloruro [dcit]

    64. Choline, Succinyl-, Dichloride

    65. Succinilcolina Cloruro

    66. Succinylcholine Chloride [usan]

    67. Chlorure De Succinilcoline [french]

    68. Cloruro Di Succinilcolina

    69. Cloruro Di Succinilcolina [italian]

    70. Suxamethonii Chloridum [inn-latin]

    71. Einecs 200-747-4

    72. Nsc 49132

    73. Cloruro De Suxametonio [inn-spanish]

    74. Unii-i9l0ddd30i

    75. Ai3-51679

    76. Anectine (tn)

    77. Quelicin (tn)

    78. Choline, Chloride, Succinate (2:1)

    79. Mfcd00038725

    80. Succinylcholine Chloride [usan:usp]

    81. Suxamethone

    82. Choline, Hydroxide, Succinate (2:1), Dihydrochloride

    83. Succinyl-bis(n-(2-oxyethyl)trimethylammonium)-dichlorid

    84. 3,8-dioxa-4,7-dioxodercan-1,10-bis(trimethylammonium)dichlorid

    85. Succinic Acid, Bis(beta-dimethylaminoethyl) Ester, Dimethochloride

    86. Chembl983

    87. Schembl41536

    88. Anhydrous Suxamethonium Chloride

    89. Succinylcholine Chloride (usp)

    90. Dtxsid1023603

    91. Anhydrous Succinylcholine Chloride

    92. Suxamethonium Chloride (anhydrous)

    93. Hms3263g22

    94. Anhydrous Succinylcholine Dichloride

    95. Succinylcholine Chloride (anhydrous)

    96. Tox21_111268

    97. Tox21_501080

    98. Anhydrous Succinyldicholine Dichloride

    99. Succinylcholine Chloride [mi]

    100. Succinylcholine Dichloride (anhydrous)

    101. Akos015961173

    102. Suxamethonium Chloride [mart.]

    103. Tox21_111268_1

    104. Ac-4688

    105. Ccg-222384

    106. Lp01080

    107. Suxamethonium Chloride [who-dd]

    108. Ethanaminium, 2,2'-((1,4-dioxo-1,4-butanediyl)bis(oxy))bis(n,n,n-trimethyl-, Dichloride

    109. Succinylcholine Chloride [vandf]

    110. Succinyldicholine Dichloride (anhydrous)

    111. Ncgc00015971-05

    112. Ncgc00261765-01

    113. Succinylcholine Chloride [usp-rs]

    114. Db-055512

    115. Eu-0101080

    116. Suxamethonium Chloride [ep Monograph]

    117. Succinylcholine Chloride [orange Book]

    118. D00766

    119. S 8251

    120. Succinylcholine Chloride [usp Monograph]

    121. Sr-01000075346

    122. Q-201750

    123. Sr-01000075346-2

    124. Q12455154

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 361.3 g/mol
    Molecular Formula C14H30Cl2N2O4
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count11
    Exact Mass360.1582628 g/mol
    Monoisotopic Mass360.1582628 g/mol
    Topological Polar Surface Area52.6 Ų
    Heavy Atom Count22
    Formal Charge0
    Complexity284
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameQuelicin preservative free
    Active IngredientSuccinylcholine chloride
    Dosage FormInjectable
    RouteInjection
    Strength20mg/ml; 100mg/ml
    Market StatusPrescription
    CompanyHospira

    2 of 2  
    Drug NameQuelicin preservative free
    Active IngredientSuccinylcholine chloride
    Dosage FormInjectable
    RouteInjection
    Strength20mg/ml; 100mg/ml
    Market StatusPrescription
    CompanyHospira

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Neuromuscular Depolarizing Agents

    Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarization of the motor end plate. These agents are primarily used as adjuvants in surgical anesthesia to cause skeletal muscle relaxation. (See all compounds classified as Neuromuscular Depolarizing Agents.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Neuromuscular Depolarizing Blockade [PE]; Depolarizing Neuromuscular Blocker [EPC]
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