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    Technical details about DSSTox_CID_3516, learn more about the structure, uses, toxicity, action, side effects and more

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    DSSTox_CID_3516

    APIs // Active Pharmaceutical Ingredients

    DEVELOPMENTS

    PharmaCompass

    Phyton is a World Leader in Plant Cell Fermentation Technology and Commercial Manufacturing.

    Athena Pharmaceutiques is a Partner of Choice for Drug Delivery & Life Cycle Management.

    2D Structure
    1. Also known as: 6620-60-6, 4-benzamido-5-(dipropylamino)-5-oxopentanoic acid, Binoside, Xylamide, Dl-proglumide, Nulsa
    Molecular Formula
    C18H26N2O4
    Molecular Weight
    334.4  g/mol
    InChI Key
    DGMKFQYCZXERLX-UHFFFAOYSA-N
    FDA UNII
    EPL8W5565D
    A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-benzamido-5-(dipropylamino)-5-oxopentanoic acid
    2.1.2 InChI
    InChI=1S/C18H26N2O4/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22)
    2.1.3 InChI Key
    DGMKFQYCZXERLX-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CCCN(CCC)C(=O)C(CCC(=O)O)NC(=O)C1=CC=CC=C1
    2.2 Other Identifiers
    2.2.1 UNII
    EPL8W5565D
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Milid

    2. Xilamide

    3. Xylamide

    2.3.2 Depositor-Supplied Synonyms

    1. 6620-60-6

    2. 4-benzamido-5-(dipropylamino)-5-oxopentanoic Acid

    3. Binoside

    4. Xylamide

    5. Dl-proglumide

    6. Nulsa

    7. Gastrotopic

    8. Midelid

    9. Ulcutin

    10. Milid

    11. Xyde

    12. Proglumidum

    13. Proglumida

    14. Pentanoic Acid, 4-(benzoylamino)-5-(dipropylamino)-5-oxo-

    15. Promid

    16. W-5219

    17. (+-)-4-benzamido-n,n-dipropylglutaramic Acid

    18. Cr-242

    19. Nsc-757841

    20. Glutaramic Acid, 4-benzamido-n,n-dipropyl-, Dl-

    21. Pentanoic Acid, 4-(benzoylamino)-5-(dipropylamino)-5-oxo-, (+-)-

    22. 4-(benzoylamino)-5-(dipropylamino)-5-oxopentanoic Acid

    23. Chembl316561

    24. Epl8w5565d

    25. Chebi:32058

    26. Milide

    27. Dsstox_cid_3516

    28. Dsstox_rid_77060

    29. Dsstox_gsid_23516

    30. Progumide

    31. Proglumidum [inn-latin]

    32. Proglumida [inn-spanish]

    33. Promide (parasympatholytic)

    34. Cr 242

    35. 24485-90-3

    36. Xylamide (gastroprotective Agent)

    37. Sr-01000002970

    38. Einecs 229-567-4

    39. 242 Dl

    40. W 5219

    41. Brn 4151696

    42. Unii-epl8w5565d

    43. Racemic Proglumide

    44. (rs)-proglumide

    45. Proglumide,(s)

    46. Proglumide [usan:inn:ban:jan]

    47. Ncgc00016676-01

    48. (+-)-proglumide

    49. Prestwick_602

    50. Cas-6620-60-6

    51. Nulsa (tn)

    52. Spectrum_001332

    53. Proglumide [mi]

    54. Dl-4-benzamido-n,n-dipropylglutaramic Acid

    55. Proglumide [inn]

    56. Proglumide [jan]

    57. Prestwick0_000240

    58. Prestwick1_000240

    59. Prestwick2_000240

    60. Prestwick3_000240

    61. Spectrum2_001406

    62. Spectrum3_001444

    63. Spectrum4_000425

    64. Spectrum5_001591

    65. Proglumide [usan]

    66. Proglumide [mart.]

    67. (+/-)-4-benzamido-n,n-dipropylglutaramic Acid

    68. Proglumide [who-dd]

    69. Lopac0_000832

    70. Schembl93339

    71. Bspbio_000319

    72. Bspbio_002907

    73. Gtpl893

    74. Kbiogr_000750

    75. Kbioss_001812

    76. Mls002154246

    77. Divk1c_000684

    78. Spectrum1501119

    79. Spbio_001452

    80. Spbio_002240

    81. Amy374

    82. Bpbio1_000351

    83. Dtxsid7023516

    84. Proglumide (jp17/usan/inn)

    85. Schembl19994752

    86. Chebi:76266

    87. Hms502c06

    88. Kbio1_000684

    89. Kbio2_001812

    90. Kbio2_004380

    91. Kbio2_006948

    92. Kbio3_002407

    93. Ninds_000684

    94. Hms1568p21

    95. Hms1921f19

    96. Hms2092d13

    97. Hms2095p21

    98. Hms2235b24

    99. Hms3262h05

    100. Hms3369d14

    101. Hms3712p21

    102. Pharmakon1600-01501119

    103. Hy-b1330

    104. Tox21_110557

    105. Tox21_500832

    106. Bdbm50014888

    107. Ccg-39024

    108. Mfcd00055071

    109. Nsc757841

    110. Akos015895810

    111. Tox21_110557_1

    112. Ac-1274

    113. Cs-8029

    114. Db13431

    115. Ks-1212

    116. Lp00832

    117. Nsc 757841

    118. Sdccgsbi-0050809.p004

    119. 4-benzamido-n,n-dipropylglutaramic Acid

    120. Idi1_000684

    121. N2-benzoyl-n,n-dipropyl-alpha-glutamine

    122. Ncgc00015623-03

    123. Ncgc00015623-04

    124. Ncgc00015623-05

    125. Ncgc00015623-06

    126. Ncgc00015623-07

    127. Ncgc00015623-10

    128. Ncgc00015623-14

    129. Ncgc00094163-01

    130. Ncgc00094163-02

    131. Ncgc00094163-03

    132. Ncgc00094163-04

    133. Ncgc00261517-01

    134. Bp166197

    135. Smr001233513

    136. Sbi-0050809.p003

    137. N(2)-benzoyl-n,n-dipropyl-alpha-glutamine

    138. Ab00052206

    139. Eu-0100832

    140. Ft-0654938

    141. M-001

    142. N2-(phenylcarbonyl)-n,n-dipropyl-a-glutamine

    143. 4-benzoylamino-4-dipropylcarbamoyl-butyric Acid

    144. D01818

    145. Rac-n(2)-benzoyl-n,n-dipropyl-alpha-glutamine

    146. Ab00052206_08

    147. 4-benzoylamino-5-dipropylamino-5-oxopentanoic Acid

    148. 620p606

    149. N~2~-(phenylcarbonyl)-n,n-dipropyl-alpha-glutamine

    150. Q7248362

    151. Sr-01000002970-2

    152. Sr-01000002970-4

    153. Sr-01000002970-7

    154. W-104770

    155. 4-(benzoylamino)-5-(dipropylamino)-5-oxovaleric Acid

    156. Brd-a44863528-001-05-8

    157. Brd-a44863528-001-08-2

    158. 4-(benzoylamino)-5-(dipropylamino)-5-oxo-pentanoic Acid

    159. Pentanoic Acid, 4-(benzoylamino)-5-(dipropylamino)-5-oxo-, (+/-)-

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 334.4 g/mol
    Molecular Formula C18H26N2O4
    XLogP32.4
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count10
    Exact Mass334.18925731 g/mol
    Monoisotopic Mass334.18925731 g/mol
    Topological Polar Surface Area86.7 Ų
    Heavy Atom Count24
    Formal Charge0
    Complexity413
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Ulcer Agents

    Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief. (See all compounds classified as Anti-Ulcer Agents.)

    4.2 ATC Code

    A - Alimentary tract and metabolism

    A02 - Drugs for acid related disorders

    A02B - Drugs for peptic ulcer and gastro-oesophageal reflux disease (gord)

    A02BX - Other drugs for peptic ulcer and gastro-oesophageal reflux disease (gord)

    A02BX06 - Proglumide

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