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    Technical details about Desoxycorticosterone, learn more about the structure, uses, toxicity, action, side effects and more

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    Desoxycorticosterone

    APIs // Active Pharmaceutical Ingredients

    PRICE INFORMATION

    MARKET PLACE

    PharmaCompass

    Minakem offers CDMO services for API & HPAPI, generics, regulatory expertise, track record performance & FDA & GMP certifications.

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    2D Structure
    Also known as: Desoxycorticosterone, 11-deoxycorticosterone, 21-hydroxyprogesterone, Deoxycorticosterone, Cortexone, 64-85-7
    Molecular Formula
    C21H30O3
    Molecular Weight
    330.5  g/mol
    InChI Key
    ZESRJSPZRDMNHY-YFWFAHHUSA-N
    FDA UNII
    40GP35YQ49
    A steroid metabolite that is the 11-deoxy derivative of CORTICOSTERONE and the 21-hydroxy derivative of PROGESTERONE
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (8S,9S,10R,13S,14S,17S)-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
    2.1.2 InChI
    InChI=1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1
    2.1.3 InChI Key
    ZESRJSPZRDMNHY-YFWFAHHUSA-N
    2.1.4 Canonical SMILES
    CC12CCC3C(C1CCC2C(=O)CO)CCC4=CC(=O)CCC34C
    2.1.5 Isomeric SMILES
    C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)CO)CCC4=CC(=O)CC[C@]34C
    2.2 Other Identifiers
    2.2.1 UNII
    40GP35YQ49
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 11 Decorticosterone

    2. 11-decorticosterone

    3. 21 Hydroxy 4 Pregnene 3,20 Dione

    4. 21 Hydroxyprogesterone

    5. 21-hydroxy-4-pregnene-3,20-dione

    6. 21-hydroxyprogesterone

    7. Cortexone

    8. Deoxycorticosterone

    9. Desoxycorticosterone

    2.3.2 Depositor-Supplied Synonyms

    1. Desoxycorticosterone

    2. 11-deoxycorticosterone

    3. 21-hydroxyprogesterone

    4. Deoxycorticosterone

    5. Cortexone

    6. 64-85-7

    7. Deoxycortone

    8. 11-desoxycorticosterone

    9. Reichstein's Substance Q

    10. 4-pregnen-21-ol-3,20-dione

    11. Desossicortone

    12. Desoxicortonum

    13. Desoxycorticosteronum

    14. Kendall's Desoxy Compound B

    15. 21-hydroxypregn-4-ene-3,20-dione

    16. 11-dehydroxycorticosterone

    17. Corticosterone, 11-deoxy-

    18. 21-hydroxy-4-pregnene-3,20-dione

    19. Progesterone, 21-hydroxy-

    20. Pregn-4-ene-3,20-dione, 21-hydroxy-

    21. Doc

    22. 1,2(3h)-deoxycorticosterone

    23. 11-deoxy Corticosterone

    24. Nsc 11319

    25. Mls000028537

    26. Chebi:16973

    27. 40gp35yq49

    28. 21-hydroxy-3,20-dioxopregn-4-ene

    29. Desoxycortone (inn)

    30. 21-hydroxy-pregn-4-ene-3,20-dione

    31. Smr000058340

    32. Desoxycortone [inn]

    33. Dsstox_cid_25254

    34. Dsstox_rid_80776

    35. Dsstox_gsid_45254

    36. (8s,9s,10r,13s,14s,17s)-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

    37. Desossicortone [dcit]

    38. Desoxicortona

    39. [4-14c]-11-deoxycorticosterone

    40. Desoxycortonum [inn-latin]

    41. Desoxicortona [inn-spanish]

    42. 1ca

    43. 11-deoxy-corticosterone

    44. 21-hydroxy-progesterone

    45. Einecs 200-596-4

    46. Desoxycortone [inn:ban]

    47. Unii-40gp35yq49

    48. Nsc-11319

    49. Desoxycorticosteron

    50. Cas-64-85-7

    51. Ncgc00016292-01

    52. 11-dcortic

    53. Doca (salt/mix)

    54. Opera_id_581

    55. Prestwick0_000957

    56. Prestwick1_000957

    57. Prestwick2_000957

    58. Prestwick3_000957

    59. Bmse000535

    60. Schembl4065

    61. Chembl1498

    62. Bspbio_000954

    63. Mls001076270

    64. Desoxycortone [mart.]

    65. Spbio_003103

    66. Desoxycortone [who-dd]

    67. Bdbm8582

    68. Bpbio1_001050

    69. Gtpl2871

    70. Deoxycorticosterone [mi]

    71. Dtxsid0045254

    72. Hydroxy-4-pregnene-3,20-dione

    73. 4-pregnene-3,20-dione-21-ol

    74. Hms1570p16

    75. Hms2097p16

    76. Hms2235g07

    77. Hms3714p16

    78. D4-pregnene-21-ol-3,20-dione

    79. Desoxycorticosterone [vandf]

    80. Zinc3833823

    81. Tox21_110356

    82. Tox21_302402

    83. Cmc_13409

    84. Lmst02030087

    85. Delta4-pregnene-21-ol-3,20-dione

    86. 21-hydroxy-d4-pregnane-3,20-dione

    87. 21-hydroxy-d4-pregnene-3,20-dione

    88. Akos005111365

    89. Tox21_110356_1

    90. Ccg-220957

    91. 21-hydroxypregn-4-ene-3,20-dione #

    92. Ncgc00021304-03

    93. Ncgc00021304-05

    94. Ncgc00256184-01

    95. 21-hydroxy-delta4-pregnane-3,20-dione

    96. 21-hydroxy-delta4-pregnene-3,20-dione

    97. 21-hydroxyprogesterone, >=97% (hplc)

    98. As-77189

    99. Hy-113414

    100. Ab00490029

    101. Cs-0059402

    102. (14beta)-21-hydroxypregn-4-ene-3,20-dione

    103. C03205

    104. D07792

    105. 003h661

    106. Q948846

    107. Sr-01000003106

    108. 21-hydroxy-.delta.4-pregnene-3,20-dione

    109. Sr-01000003106-2

    110. W-104814

    111. Brd-k98521173-001-03-8

    112. 21-hydroxyprogesterone 100 Microg/ml In Methanol/water

    113. Bd5d7bc9-0cd8-404e-9ba0-f670962012f8

    114. 4-pregnen-21-ol-3,20-dione; Doc; 21-hydroxyprogesterone

    115. (1s,2r,10s,11s,14s,15s)-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadec-6-en-5-one

    116. (8s,10r,13s,17s)-17-(2-hydroxy-acetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

    2.4 Create Date
    2004-09-16
    3 Chemical and Physical Properties
    Molecular Weight 330.5 g/mol
    Molecular Formula C21H30O3
    XLogP32.9
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count2
    Exact Mass330.21949481 g/mol
    Monoisotopic Mass330.21949481 g/mol
    Topological Polar Surface Area54.4 Ų
    Heavy Atom Count24
    Formal Charge0
    Complexity606
    Isotope Atom Count0
    Defined Atom Stereocenter Count6
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Mineralocorticoids

    A group of CORTICOSTEROIDS primarily associated with water and electrolyte balance. This is accomplished through the effect on ION TRANSPORT in renal tubules, resulting in retention of sodium and loss of potassium. Mineralocorticoid secretion is itself regulated by PLASMA VOLUME, serum potassium, and ANGIOTENSIN II. (See all compounds classified as Mineralocorticoids.)

    4.2 ATC Code

    H - Systemic hormonal preparations, excl. sex hormones and insulins

    H02 - Corticosteroids for systemic use

    H02A - Corticosteroids for systemic use, plain

    H02AA - Mineralocorticoids

    H02AA03 - Desoxycortone

    4.3 Metabolism/Metabolites

    21-hydroxy-progesterone is a known human metabolite of progesterone.

    S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560

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