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    Technical details about Clopamide, learn more about the structure, uses, toxicity, action, side effects and more

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    Clopamide

    APIs // Active Pharmaceutical Ingredients

    DOSSIERs // Finished Dosage Forms

    GLOBAL SALES INFORMATION

    REF. STANDARDS & IMPURITIES

    PharmaCompass

    Inke S.A: APIs manufacturing plant.

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    2D Structure
    1. Also known as: Clopamide, Chlosudimeprimylum, Mls000551289, Smr000145215, Chlosudimeprimyl, Adurix; aquex; brinaldix; chlosudimeprimyl;clopamidum; dt 327
    Molecular Formula
    C14H20ClN3O3S
    Molecular Weight
    345.8  g/mol
    InChI Key
    LBXHRAWDUMTPSE-UHFFFAOYSA-N
    A sulfamoylbenzamide piperidine. It is considered a thiazide-like diuretic.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-chloro-N-(2,6-dimethylpiperidin-1-yl)-3-sulfamoylbenzamide
    2.1.2 InChI
    InChI=1S/C14H20ClN3O3S/c1-9-4-3-5-10(2)18(9)17-14(19)11-6-7-12(15)13(8-11)22(16,20)21/h6-10H,3-5H2,1-2H3,(H,17,19)(H2,16,20,21)
    2.1.3 InChI Key
    LBXHRAWDUMTPSE-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1CCCC(N1NC(=O)C2=CC(=C(C=C2)Cl)S(=O)(=O)N)C
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. Brinaldix

    2. Brinedine

    3. Clopamide

    2.2.2 Depositor-Supplied Synonyms

    1. Clopamide

    2. Chlosudimeprimylum

    3. Mls000551289

    4. Smr000145215

    5. Chlosudimeprimyl

    6. Adurix; Aquex; Brinaldix; Chlosudimeprimyl;clopamidum; Dt 327

    7. Dt-327

    8. 4-chloro-n-(2,6-dimethyl-piperidin-1-yl)-3-sulfamoyl-benzamide

    9. Chlorsudimeprimyl

    10. Dt 327

    11. Ncgc00016527-01

    12. Cas-636-54-4

    13. Spectrum_001568

    14. Opera_id_864

    15. Prestwick0_000354

    16. Prestwick1_000354

    17. Prestwick2_000354

    18. Spectrum2_001595

    19. Spectrum3_001891

    20. Spectrum4_000207

    21. Spectrum5_001563

    22. Dsstox_cid_2847

    23. Dsstox_rid_76757

    24. Dsstox_gsid_22847

    25. Oprea1_353822

    26. Bspbio_003422

    27. Kbiogr_000813

    28. Kbioss_002048

    29. Mls001201776

    30. Mls006010787

    31. Divk1c_000946

    32. Schembl124598

    33. Spectrum1503919

    34. Spbio_001590

    35. Spbio_002368

    36. Chembl1361347

    37. Dtxsid1022847

    38. Chebi:95210

    39. Hms502p08

    40. Kbio1_000946

    41. Kbio2_002048

    42. Kbio2_004616

    43. Kbio2_007184

    44. Kbio3_002925

    45. Ninds_000946

    46. 4-chloro-n-(2,6-dimethyl-1-piperidinyl)-3-sulfamoylbenzamide

    47. Hms1569g09

    48. Hms2093k21

    49. Hms2233p13

    50. Hms3371c11

    51. Hms3374m01

    52. Tox21_110475

    53. Bdbm50237613

    54. Ccg-39373

    55. Akos024374908

    56. Idi1_000946

    57. Ncgc00016527-03

    58. Ncgc00018272-02

    59. Ncgc00018272-03

    60. Ncgc00096000-01

    61. Ncgc00096000-02

    62. Ls-14327

    63. Sbi-0051860.p002

    64. Db-054517

    65. Ft-0603202

    66. Sw196897-2

    67. Sr-01000675440

    68. Q5135114

    69. Sr-01000675440-2

    70. Brd-a85651701-001-03-1

    71. 4-chloro-n-(cis-2,6-dimethylpiperidino)-3-sulfamoylbenzamide

    72. 3-(aminosulfonyl)-4-chloro-n-(2,6-dimethylpiperidin-1-yl)benzamide

    73. Benzamide, 4-chloro-n-(2,6-dimethylpiperidino)-3-sulfamoyl-, Cis-

    74. 3-(aminosulfonyl)-4-chloro-n-(2,6-dimethyl-1-piperidinyl)benzamide-, Cis-

    2.3 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 345.8 g/mol
    Molecular Formula C14H20ClN3O3S
    XLogP32.3
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count3
    Exact Mass345.0913904 g/mol
    Monoisotopic Mass345.0913904 g/mol
    Topological Polar Surface Area101 Ų
    Heavy Atom Count22
    Formal Charge0
    Complexity498
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count2
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Diuretics

    Agents that promote the excretion of urine through their effects on kidney function. (See all compounds classified as Diuretics.)

    4.2 ATC Code

    C - Cardiovascular system

    C03 - Diuretics

    C03B - Low-ceiling diuretics, excl. thiazides

    C03BA - Sulfonamides, plain

    C03BA03 - Clopamide

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