loader
Please Wait
Applying Filters...

Suanfarma Suanfarma

X
menu

    Market Place

    Market Place

    Post Enquiry

    Post Enquiry
    menu

    Technical details about Chlorothiazide Sodium, learn more about the structure, uses, toxicity, action, side effects and more

    Client Email Product
    Menu

    Chlorothiazide Sodium

    APIs // Active Pharmaceutical Ingredients

    DOSSIERs // Finished Dosage Forms

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    MARKET PLACE

    DIGITAL CONTENT

    PharmaCompass

    Inke S.A: APIs manufacturing plant.

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    2D Structure
    1. Also known as: 7085-44-1, Chlorothiazide sodium [usan:usp], Chlorothiazide (sodium), Chlorothiazide sodium salt, Sn86fg7n2k, 6-chloro-2h-1,2,4-benzothiadiazine-7-sulfonamide, 1,1-dioxide, monosodium salt
    Molecular Formula
    C7H5ClN3NaO4S2
    Molecular Weight
    317.7  g/mol
    InChI Key
    CPIWHAFLBZQYLQ-UHFFFAOYSA-N
    FDA UNII
    SN86FG7N2K
    Chlorothiazide Sodium is the sodium salt form of chlorothiazide, a short-acting, benzothiadiazinesulfonamide derivative belonging to the class of thiazide diuretics. Chlorothiazide is excreted unchanged by the kidneys.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    sodium;6-chloro-1,1-dioxo-16,2,4-benzothiadiazin-2-ide-7-sulfonamide
    2.1.2 InChI
    InChI=1S/C7H5ClN3O4S2.Na/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5;/h1-3H,(H2-,9,10,11,12,13);/q-1;+1
    2.1.3 InChI Key
    CPIWHAFLBZQYLQ-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)[N-]C=N2.[Na+]
    2.2 Other Identifiers
    2.2.1 UNII
    SN86FG7N2K
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. 7085-44-1

    2. Chlorothiazide Sodium [usan:usp]

    3. Chlorothiazide (sodium)

    4. Chlorothiazide Sodium Salt

    5. Sn86fg7n2k

    6. 6-chloro-2h-1,2,4-benzothiadiazine-7-sulfonamide, 1,1-dioxide, Monosodium Salt

    7. 2h-1,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-, 1,1-dioxide, Monosodium Salt

    8. Diuril Sodium

    9. Sodium Diuril

    10. Diuril (tn)

    11. Chlorothiazide Sodium [usan]

    12. Einecs 230-387-3

    13. Unii-sn86fg7n2k

    14. Lyovac Diuril

    15. Chlorothiazide Sodium (usp)

    16. Chembl1200616

    17. Hy-b0224a

    18. Dtxsid00221091

    19. Chlorothiazide Sodium [vandf]

    20. Chlorothiazide Sodium [mart.]

    21. Chlorothiazide Sodium [who-dd]

    22. Chlorothiazide Sodium Salt [mi]

    23. Chlorothiazide Sodium [orange Book]

    24. Chlorothiazide Sodium [usp Impurity]

    25. Cs-0030911

    26. D03471

    27. Q27289300

    2.4 Create Date
    2008-02-05
    3 Chemical and Physical Properties
    Molecular Weight 317.7 g/mol
    Molecular Formula C7H5ClN3NaO4S2
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count7
    Rotatable Bond Count1
    Exact Mass316.9307700 g/mol
    Monoisotopic Mass316.9307700 g/mol
    Topological Polar Surface Area124 Ų
    Heavy Atom Count18
    Formal Charge0
    Complexity538
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameChlorothiazide sodium
    Active IngredientChlorothiazide sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 500mg base/vial
    Market StatusPrescription
    CompanyFresenius Kabi Usa; Mylan Institutional; Luitpold; Sun Pharma Global

    2 of 2  
    Drug NameChlorothiazide sodium
    Active IngredientChlorothiazide sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 500mg base/vial
    Market StatusPrescription
    CompanyFresenius Kabi Usa; Mylan Institutional; Luitpold; Sun Pharma Global

    5 Pharmacology and Biochemistry
    5.1 FDA Pharmacological Classification
    5.1.1 Pharmacological Classes
    Thiazide Diuretic [EPC]; Thiazides [CS]; Increased Diuresis [PE]
    Post Enquiry
    POST ENQUIRY