Please Wait
Applying Filters...
menu
    • menu
    Athena Pharmaceutiques is a Partner of Choice for Drug Delivery & Life Cycle Management.

    Virtual Booth

    Contact Supplier

    Kikkoman Biochemifa Company advances global health and safety through precision-driven innovation in biotech and food testing.

    Virtual Booth

    Contact Supplier

    Rusan Pharma: Over 30 years of specializing in the treatment of Addiction and Pain Management.

    Virtual Booth

    Contact Supplier

    TransoPharm USA works in the Sourcing and Management of Active Pharmaceutical Ingredients.

    Virtual Booth

    Contact Supplier

    Moehs Group, a reference company in the production of pharmaceutical active ingredients.

    Virtual Booth

    Contact Supplier

    pharmacompass-2-m-2025-10-20

    Virtual Booth

    An Enquiry

    Menu

    Carvedilol Phosphate

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    DRUG PRODUCT COMPOSITIONS

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    DIGITAL CONTENT

    GLOBAL SALES INFORMATION

    MARKET PLACE

    PATENTS & EXCLUSIVITIES

    PharmaCompass
    $ API Ref.Price (USD/KG) : 2,384Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: Carvedilol phosphate, 1196658-85-1, Carvedilol (phosphate hemihydrate), 4s19o2f64l, Bm 14190 (phosphate hemihydrate), 2-propanol, 1-(9h-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-, phosphate, hydrate (1:1:1)
    Molecular Formula
    C24H31N2O9P
    Molecular Weight
    522.5  g/mol
    InChI Key
    JAYBFQXVKDGMFT-UHFFFAOYSA-N
    FDA UNII
    4S19O2F64L
    Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity. The S enantiomer of carvedilol nonselectively binds to and blocks beta-adrenergic receptors, thereby exerting negative inotropic and chronotropic effects, and leading to a reduction in cardiac output. In addition, both enantiomers of carvedilol bind to and block alpha 1-adrenergic receptors, thereby causing vasodilation and reducing peripheral vascular resistance.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol;phosphoric acid;hydrate
    2.1.2 InChI
    InChI=1S/C24H26N2O4.H3O4P.H2O/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20;1-5(2,3)4;/h2-12,17,25-27H,13-16H2,1H3;(H3,1,2,3,4);1H2
    2.1.3 InChI Key
    JAYBFQXVKDGMFT-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    COC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O.O.OP(=O)(O)O
    2.2 Other Identifiers
    2.2.1 UNII
    4S19O2F64L
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. Carvedilol Phosphate

    2. 1196658-85-1

    3. Carvedilol (phosphate Hemihydrate)

    4. 4s19o2f64l

    5. Bm 14190 (phosphate Hemihydrate)

    6. 2-propanol, 1-(9h-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-, Phosphate, Hydrate (1:1:1)

    7. 2-propanol,1-(9h-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-,phosphate (salt), Hydrate (2:2:1)

    8. Unii-4s19o2f64l

    9. Schembl599530

    10. 309c892

    11. Q27260413

    12. 1-9h-(carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol Phosphate Hemihydrate

    2.4 Create Date
    2008-01-22
    3 Chemical and Physical Properties
    Molecular Weight 522.5 g/mol
    Molecular Formula C24H31N2O9P
    Hydrogen Bond Donor Count7
    Hydrogen Bond Acceptor Count10
    Rotatable Bond Count10
    Exact Mass522.17671757 g/mol
    Monoisotopic Mass522.17671757 g/mol
    Topological Polar Surface Area155 Ų
    Heavy Atom Count36
    Formal Charge0
    Complexity557
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameCoreg cr
    PubMed HealthCarvedilol (By mouth)
    Drug ClassesAntianginal, Antihypertensive, Cardiovascular Agent
    Active IngredientCarvedilol phosphate
    Dosage FormCapsule, extended release
    RouteOral
    Strength10mg; 80mg; 40mg; 20mg
    Market StatusPrescription
    CompanySb Pharmco

    2 of 2  
    Drug NameCoreg cr
    PubMed HealthCarvedilol (By mouth)
    Drug ClassesAntianginal, Antihypertensive, Cardiovascular Agent
    Active IngredientCarvedilol phosphate
    Dosage FormCapsule, extended release
    RouteOral
    Strength10mg; 80mg; 40mg; 20mg
    Market StatusPrescription
    CompanySb Pharmco

    5 Pharmacology and Biochemistry
    5.1 FDA Pharmacological Classification
    5.1.1 Pharmacological Classes
    Adrenergic beta1-Antagonists [MoA]; Adrenergic beta2-Antagonists [MoA]; alpha-Adrenergic Blocker [EPC]; beta-Adrenergic Blocker [EPC]; Adrenergic alpha-Antagonists [MoA]