Please Wait
Applying Filters...
menu
    • menu
    Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

    Virtual Booth

    Contact Supplier

    DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

    Virtual Booth

    Contact Supplier

    pharmacompass-1-m-2025-12-22

    Virtual Booth

    An Enquiry

    AbbVie CDMO has been working with global companies to develop, manufacture & scale biopharmaceutical products.

    Virtual Booth

    Contact Supplier

    HTL Biotechnology is a French biotech & a global leader in the responsible development & production of pharma-grade biopolymers.

    Virtual Booth

    Contact Supplier

    pharmacompass-2-m-2025-11-03

    Virtual Booth

    An Enquiry

    Menu

    BAY1895344

    DEVELOPMENTS

    PharmaCompass
    Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: 1876467-74-1, Bay-1895344, Bay 1895344, Bay1895344, Bay-1895344 hcl, 7n13ik9lnh
    Molecular Formula
    C20H21N7O
    Molecular Weight
    375.4  g/mol
    InChI Key
    YBXRSCXGRPSTMW-CYBMUJFWSA-N
    FDA UNII
    7N13IK9LNH
    Elimusertib is an orally available ataxia telangiectasia and Rad3-related (ATR)-specific kinase inhibitor, with potential antineoplastic activity. Upon oral administration, elimusertib selectively binds to and inhibits the activity of ATR, which prevents ATR-mediated signaling. This inhibits DNA damage checkpoint activation, disrupts DNA damage repair and induces apoptosis in ATR-overexpressing tumor cells. ATR, a serine/threonine protein kinase upregulated in a variety of cancer cell types, plays a key role in DNA repair, cell cycle progression and cell survival.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (3R)-3-methyl-4-[4-(2-methylpyrazol-3-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine
    2.1.2 InChI
    InChI=1S/C20H21N7O/c1-13-12-28-10-9-27(13)18-11-15(17-5-8-23-26(17)2)14-3-6-21-20(19(14)24-18)16-4-7-22-25-16/h3-8,11,13H,9-10,12H2,1-2H3,(H,22,25)/t13-/m1/s1
    2.1.3 InChI Key
    YBXRSCXGRPSTMW-CYBMUJFWSA-N
    2.1.4 Canonical SMILES
    CC1COCCN1C2=NC3=C(C=CN=C3C4=CC=NN4)C(=C2)C5=CC=NN5C
    2.1.5 Isomeric SMILES
    C[C@@H]1COCCN1C2=NC3=C(C=CN=C3C4=CC=NN4)C(=C2)C5=CC=NN5C
    2.2 Other Identifiers
    2.2.1 UNII
    7N13IK9LNH
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. (r)-3-methyl-4-(4-(1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-3-yl)-1,7-naphthyridin-2-yl)morpholine

    2. Bay 1895344

    2.3.2 Depositor-Supplied Synonyms

    1. 1876467-74-1

    2. Bay-1895344

    3. Bay 1895344

    4. Bay1895344

    5. Bay-1895344 Hcl

    6. 7n13ik9lnh

    7. (r)-3-methyl-4-(4-(1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-3-yl)-1,7-naphthyridin-2-yl)morpholine

    8. (3r)-3-methyl-4-[4-(2-methylpyrazol-3-yl)-8-(1h-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine

    9. (r)-3-methyl-4-(4-(1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine

    10. Elimusertib [inn]

    11. Unii-7n13ik9lnh

    12. Elimusertib [who-dd]

    13. Chembl4647810

    14. Schembl17501318

    15. Schembl21756640

    16. Gtpl10354

    17. Elimusertib (bay-1895344)

    18. Ex-a1662

    19. Nsc800525

    20. Nsc817275

    21. S9864

    22. Nsc-800525

    23. Nsc-817275

    24. Ac-30337

    25. Bb178556

    26. Bs-15734

    27. Hy-101566

    28. Cs-0021722

    29. A903444

    30. 1,7-naphthyridine, 2-((3r)-3-methyl-4-morpholinyl)-4-(1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-3-yl)-

    2.4 Create Date
    2016-04-09
    3 Chemical and Physical Properties
    Molecular Weight 375.4 g/mol
    Molecular Formula C20H21N7O
    XLogP31.6
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count3
    Exact Mass375.18075832 g/mol
    Monoisotopic Mass375.18075832 g/mol
    Topological Polar Surface Area84.8 Ų
    Heavy Atom Count28
    Formal Charge0
    Complexity537
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    • Privacy policy
    • Terms and conditions
    • Disclaimers
    • LinkedIn
    • Product listings are provided for informational purposes only. We do not supply or sell any products. Any products that may be covered by patent(s) are supplied solely for uses permitted under Section 107A of the Indian Patents Act and not for commercial sale.