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Technical details about Alpharma brand of metylperon hydrochloride, learn more about the structure, uses, toxicity, action, side effects and more

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2D Structure
Also known as: 1622-79-3, 1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one hydrochloride, Methylperone hydrochloride, Melperone hcl, Nsc-760102, 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone hydrochloride
Molecular Formula
C16H23ClFNO
Molecular Weight
299.81  g/mol
InChI Key
MQHYXXIJLKFQGY-UHFFFAOYSA-N
FDA UNII
88G640374K

1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one;hydrochloride
2.1.2 InChI
InChI=1S/C16H22FNO.ClH/c1-13-8-11-18(12-9-13)10-2-3-16(19)14-4-6-15(17)7-5-14;/h4-7,13H,2-3,8-12H2,1H3;1H
2.1.3 InChI Key
MQHYXXIJLKFQGY-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1CCN(CC1)CCCC(=O)C2=CC=C(C=C2)F.Cl
2.2 Other Identifiers
2.2.1 UNII
88G640374K
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Buronil

2. Eunerpan

3. Harmosin

4. Libernal

5. Mel-puren

6. Melneurin

7. Melperomerck

8. Melperon

9. Melperon Abz

10. Melperon Al

11. Melperon Azu

12. Melperon Beta

13. Melperon Fg 5111

14. Melperon Stada

15. Melperon Von Ct

16. Melperon-neuraxpharm

17. Melperon-ratiopharm

18. Melperon-rph

19. Melperon-teva

20. Melperone

21. Methylperon

22. Metylperon

23. Metylperon Hydrochloride

2.3.2 Depositor-Supplied Synonyms

1. 1622-79-3

2. 1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one Hydrochloride

3. Methylperone Hydrochloride

4. Melperone Hcl

5. Nsc-760102

6. 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone Hydrochloride

7. 1-butanone, 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-, Hydrochloride (1:1)

8. 88g640374k

9. Buronil (tn)

10. Metylperon Hydrochloride

11. Mls001424296

12. Chembl4551527

13. Dtxsid10936649

14. Pharmakon1600-01502266

15. Melperone Hydrochloride [mi]

16. Mfcd00270922

17. Nsc760102

18. Akos016007345

19. Ccg-101176

20. Melperone Hydrochloride [mart.]

21. Nc00426

22. Melperone Hydrochloride [who-dd]

23. As-77510

24. Smr000468736

25. B7078

26. Cs-0024369

27. D08172

28. J-009916

29. Q27269931

30. 1-[3-(p-fluorobenzoyl)propyl]-4-methylpiperaziniumchloride

31. 1-(4-fluorophenyl)-4-(4-methyl-piperidin-1-yl)butan-1-one Hydrochloride

32. 1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one Hcl

33. 1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one;hydrochloride

34. 1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-onehydrochloride

35. 1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one--hydrogen Chloride (1/1)

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 299.81 g/mol
Molecular Formula C16H23ClFNO
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Exact Mass299.1452202 g/mol
Monoisotopic Mass299.1452202 g/mol
Topological Polar Surface Area20.3 Ų
Heavy Atom Count20
Formal Charge0
Complexity279
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antipsychotic Agents

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)


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