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2D Structure
Also known as: Dibromine, 7726-95-6, Molecular bromine, Brom, Brome, Bromo
Molecular Formula
Br2
Molecular Weight
159.81  g/mol
InChI Key
GDTBXPJZTBHREO-UHFFFAOYSA-N
FDA UNII
SBV4XY874G

A halogen with the atomic symbol Br, atomic number 35, and atomic weight 79.904. It is a volatile reddish-brown liquid that gives off suffocating vapors, is corrosive to the skin, and may cause severe gastroenteritis if ingested.
1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
molecular bromine
2.1.2 InChI
InChI=1S/Br2/c1-2
2.1.3 InChI Key
GDTBXPJZTBHREO-UHFFFAOYSA-N
2.2 Other Identifiers
2.2.1 UNII
SBV4XY874G
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Bromine 79

2. Bromine-79

2.3.2 Depositor-Supplied Synonyms

1. Dibromine

2. 7726-95-6

3. Molecular Bromine

4. Brom

5. Brome

6. Bromo

7. Broom

8. Caswell No. 112

9. Sbv4xy874g

10. Bromium

11. Hsdb 514

12. Einecs 231-778-1

13. Unii-sbv4xy874g

14. Epa Pesticide Chemical Code 008701

15. Br2

16. Dtxsid1035238

17. Chebi:29224

18. Bromine (mart.)

19. Bromine [mart.]

20. Ec 231-778-1

21. Bromine 79

22. Total Bromine

23. Bromium 6c

24. Bromium 30c

25. Dtxcid9015238

26. Usepa/opp Pesticide Code: 008701

27. 231-778-1

28. Br

29. Bromine (acgih:osha)

30. Chebi:33117

31. D-149

32. Mfcd00010896

33. Bromo [italian]

34. Bromo [spanish]

35. Brome [french]

36. Brom [german]

37. Broom [dutch]

38. Dibromane

39. Bromoniumbromid

40. Bromine-bromide

41. Bromine Liquid

42. Bromo-

43. Bromine Water, Cp

44. Un1744

45. Bromine, Reagent Grade

46. Bromine [hsdb]

47. Bromium [hpus]

48. Bromine [mi]

49. Bromine [who-dd]

50. Bromine, Lr, >=99%

51. Bromine, P.a., 99.5%

52. Bromine Number - 2 G/100 G

53. Bromine Index - 10 Mg/100 G

54. Bromine Number - 10 G/100 G

55. Bcp26202

56. Bromine Index - 100 Mg/100 G

57. Bromine, Acs Reagent, >=99.5%

58. Br1014

59. Bromine Index - 1000 Mg/100 G

60. Akos015897100

61. Un 1744

62. Bromine, Saj First Grade, >=97.0%

63. Bromine, >=99.99% Trace Metals Basis

64. Bromine, Jis Special Grade, >=99.0%

65. Bp-24346

66. B2414

67. Bromine, Puriss. P.a., >=99.0% (rt)

68. Ns00075687

69. Q2685750

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 159.81 g/mol
Molecular Formula Br2
XLogP31.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count0
Rotatable Bond Count0
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area0
Heavy Atom Count2
Formal Charge0
Complexity0
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Minimum/Potential Fatal Human Dose

An oral dose of 1 mL is regarded as lethal in adults.

European Commission/European Chemical Substances Information System (ESIS); IUCLID Dataset, Bromine (7726-95-6) p. 40 (2000). Available from, as of October 2, 2014: https://esis.jrc.ec.europa.eu/


Concentration of 11-23 mg/cu m produces severe choking ... 30-60 mg/cu m is extremely dangerous ... 200 mg/cu m would prove fatal in very short time ... vapors can cause acute as well as chronic poisoning .. it has cumulative properties ..

European Commission/European Chemical Substances Information System (ESIS); IUCLID Dataset, Bromine (7726-95-6) p. 37 (2000). Available from, as of October 2, 2014: https://esis.jrc.ec.europa.eu/


5 Pharmacology and Biochemistry
5.1 Absorption, Distribution and Excretion

Bromine vapors enter body by respiratory system, skin and digestive system. It has cumulative properties, being deposited in tissues as bromides.

European Commission/European Chemical Substances Information System (ESIS); IUCLID Dataset, Bromine (7726-95-6) p. 35 (2000). Available from, as of October 2, 2014: https://esis.jrc.ec.europa.eu/


5.2 Metabolism/Metabolites

In water, and living organisms, bromine forms bromide.

USEPA/Office of Pesticide Programs; Reregistration Eligibility Decision Document - Bromine p. 6-10. EPA-738-F-93-023 (December 1998) Available from, as of June 7, 2007: https://www.epa.gov/pesticides/reregistration/status.htm


Bromine is mainly absorbed via inhalation, but may also enter the body through dermal contact. Bromine salts can be ingested. Due to its reactivity, bromine quickly forms bromide and may be deposited in the tissues, displacing other halogens. (L626)


5.3 Biological Half-Life

Biological half-lives of bromine in 15 different organs and tissues of the rat, in addition to the whole-body half-life, were determined by measuring the radioactive concentration of 82Br-bromide in samples of tissues collected at the time intervals of 12-396 hr from animals that continuously (up to 17 d) received 82Br-labeled bromide in their drinking water. The half-life values, calculated from the experimental data by the method of gradual estimates of the parameters in question with the SPSS statistical program, ranged from 94.3 + or - 14.6 hr in the thyroid gland to 235.0 + or - 88.9 hr in liver. In most of the studied tissues, the biological half-lives of bromine were shorter than in the whole body, in which it equaled 197.8 + or - 22.2 hr. Significant correlation between the values of the steady-state concentration of bromide and of the biological half-life was found for most tissues (except for liver). ...

PMID:10999430 Pavelka S et al; Biol Trace Elem Res. 76 (1): 57-66 (2000)


The biological half-life for bromide through ingestion is 12 to 30 days.

IPCS INCHEM; Poisons Information Monographs, Bromine (PIM 080). Available from, as of June 25, 2007: https://www.inchem.org/pages/pims.html


Bromide has a half-life of about 12 days in the human body.

USEPA/Office of Pesticide Programs; Reregistration Eligibility Decision Document - Bromine p. 6-10. EPA-738-F-93-023 (December 1998) Available from, as of June 7th, 2007: https://www.epa.gov/pesticides/reregistration/status.htm


10.5 days and in an average clearance of 0.68 mL/min.

Seiler, H.G., H. Sigel and A. Sigel (eds.). Handbook on the Toxicity of Inorganic Compounds. New York, NY: Marcel Dekker, Inc. 1988., p. 147


5.4 Mechanism of Action

Due to its potent oxidatizing action, bromine liberates nascent oxygen or oxygen free radicals from the water present in mucous membranes. Nascent oxygen is a potent oxidizer, capable of producing tissue damage. The extent of the damage is dependent on the dose of bromine and the availability of water to react with it. In addition, the formation of hydrobromic and bromic acids will result in secondary irritation during the reaction.

IPCS INCHEM; Poisons Information Monographs, Bromine (PIM 080). Available from, as of June 25, 2007: https://www.inchem.org/pages/pims.html