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    Technical details about 25332-13-2, learn more about the structure, uses, toxicity, action, side effects and more

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    25332-13-2

    APIs // Active Pharmaceutical Ingredients

    PRICE INFORMATION

    PharmaCompass

    Phyton is a World Leader in Plant Cell Fermentation Technology and Commercial Manufacturing.

    Athena Pharmaceutiques is a Partner of Choice for Drug Delivery & Life Cycle Management.

    2D Structure
    Also known as: 25332-13-2, Trimipramine mesilate, Y62g268p6x, 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-n,n,2-trimethylpropan-1-amine;methanesulfonic acid, Unii-y62g268p6x, Einecs 246-852-9
    Molecular Formula
    C21H30N2O3S
    Molecular Weight
    390.5  g/mol
    InChI Key
    KPPOZKAGJSXVND-UHFFFAOYSA-N
    FDA UNII
    Y62G268P6X
    Tricyclic antidepressant similar to IMIPRAMINE, but with more antihistaminic and sedative properties.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethylpropan-1-amine;methanesulfonic acid
    2.1.2 InChI
    InChI=1S/C20H26N2.CH4O3S/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22;1-5(2,3)4/h4-11,16H,12-15H2,1-3H3;1H3,(H,2,3,4)
    2.1.3 InChI Key
    KPPOZKAGJSXVND-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(CN1C2=CC=CC=C2CCC3=CC=CC=C31)CN(C)C.CS(=O)(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    Y62G268P6X
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 10,11 Dihydro-n,n,beta-trimethyl-5h-dibenz(b,f)azepine-5-propanamine

    2. Apo Trimip

    3. Apo-trimip

    4. Apotrimip

    5. Beta, Trimipramin

    6. Eldoral

    7. Herphonal

    8. Novo Tripramine

    9. Novo-tripramine

    10. Novotripramine

    11. Nu Trimipramine

    12. Nu-trimipramine

    13. Nutrimipramine

    14. Rhotrimine

    15. Stangyl

    16. Surmontil

    17. Surmontil Maleate

    18. Trimeprimine

    19. Trimidura

    20. Trimineurin

    21. Trimineurin Maleate

    22. Trimipramin Azu

    23. Trimipramin Beta

    24. Trimipramin Neurazpharm

    25. Trimipramin Stada

    26. Trimipramin-neurazpharm

    27. Trimipramine

    28. Trimipramine Maleate

    29. Trimipramine Maleate (1:1)

    30. Trimipramine Maleate (1:1), (+)-isomer

    31. Trimipramine Maleate (1:1), (+-)-isomer

    32. Trimipramine Maleate (1:1), (-)-isomer

    33. Trimipramine Monohydrochloride

    34. Trimipramine, (+-)-isomer

    35. Trimipramine, (-)-isomer

    36. Trimipraminneurazpharm

    2.3.2 Depositor-Supplied Synonyms

    1. 25332-13-2

    2. Trimipramine Mesilate

    3. Y62g268p6x

    4. 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-n,n,2-trimethylpropan-1-amine;methanesulfonic Acid

    5. Unii-y62g268p6x

    6. Einecs 246-852-9

    7. 10,11-dihydro-n,n,beta-trimethyl-5h-dibenz(b,f)azepine-5-propylamine Monomethanesulphonate

    8. Schembl6511858

    9. Dtxsid40948174

    10. Trimipramine Mesilate [who-dd]

    11. Trimipramine Mesylate/trimipramine Mesilate

    12. Q27294300

    13. 5h-dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-n,n,.beta.-trimethyl-, Methanesulfonate (1:1)

    14. Methanesulfonic Acid--3-(10,11-dihydro-5h-dibenzo[b,f]azepin-5-yl)-n,n,2-trimethylpropan-1-amine (1/1)

    2.4 Create Date
    2005-08-09
    3 Chemical and Physical Properties
    Molecular Weight 390.5 g/mol
    Molecular Formula C21H30N2O3S
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count4
    Exact Mass390.19771400 g/mol
    Monoisotopic Mass390.19771400 g/mol
    Topological Polar Surface Area69.2 Ų
    Heavy Atom Count27
    Formal Charge0
    Complexity409
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Antidepressive Agents, Tricyclic

    Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system. (See all compounds classified as Antidepressive Agents, Tricyclic.)

    Adrenergic Uptake Inhibitors

    Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (ANTIDEPRESSIVE AGENTS, TRICYCLIC) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. (See all compounds classified as Adrenergic Uptake Inhibitors.)

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