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    Technical details about 169D1260Km, learn more about the structure, uses, toxicity, action, side effects and more

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    169D1260Km

    PharmaCompass

    Biopharma Group offers CDMO services with expertise in contract R&D for dried products & liquid formulations.

    Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

    2D Structure
    1. Also known as: Nitroprusside [who-dd], Dtxsid2046963, 169d1260km
    Molecular Formula
    C5FeN6O-2
    Molecular Weight
    215.94  g/mol
    InChI Key
    YEESUBCSWGVPCE-UHFFFAOYSA-N
    FDA UNII
    169D1260KM
    A powerful vasodilator used in emergencies to lower blood pressure or to improve cardiac function. It is also an indicator for free sulfhydryl groups in proteins.
    Nitroprusside is a Vasodilator. The physiologic effect of nitroprusside is by means of Vasodilation.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    azanylidyneoxidanium;iron(2+);pentacyanide
    2.1.2 InChI
    InChI=1S/5CN.Fe.NO/c5*1-2;;1-2/q5*-1;+2;+1
    2.1.3 InChI Key
    YEESUBCSWGVPCE-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    [C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.N#[O+].[Fe+2]
    2.2 Other Identifiers
    2.2.1 UNII
    169D1260KM
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Cyanonitrosylferrate

    2. Disodium Salt Nitroprusside

    3. Ketostix

    4. Naniprus

    5. Nipride

    6. Nipruton

    7. Nitriate

    8. Nitroferricyanide

    9. Nitropress

    10. Nitroprussiat Fides

    11. Nitroprusside

    12. Nitroprusside, Disodium Salt

    13. Nitroprusside, Disodium Salt, Dihydrate

    14. Nitroprusside, Sodium

    15. Sodium Nitroprusside

    2.3.2 Depositor-Supplied Synonyms

    1. Nitroprusside [who-dd]

    2. Dtxsid2046963

    3. 169d1260km

    2.4 Create Date
    2017-02-17
    3 Chemical and Physical Properties
    Molecular Weight 215.94 g/mol
    Molecular Formula C5FeN6O-2
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count11
    Rotatable Bond Count0
    Exact Mass215.948294 g/mol
    Monoisotopic Mass215.948294 g/mol
    Topological Polar Surface Area144 Ų
    Heavy Atom Count13
    Formal Charge-2
    Complexity20
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count7
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Antihypertensive Agents

    Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)

    Indicators and Reagents

    Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant and Hackh's Chemical Dictionary, 5th ed, p301, p499) (See all compounds classified as Indicators and Reagents.)

    Nitric Oxide Donors

    A diverse group of agents, with unique chemical structures and biochemical requirements, which generate NITRIC OXIDE. These compounds have been used in the treatment of cardiovascular diseases and the management of acute myocardial infarction, acute and chronic congestive heart failure, and surgical control of blood pressure. (Adv Pharmacol 1995;34:361-81) (See all compounds classified as Nitric Oxide Donors.)

    Vasodilator Agents

    Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)

    4.2 FDA Pharmacological Classification
    4.2.1 Active Moiety
    NITROPRUSSIDE
    4.2.2 FDA UNII
    169D1260KM
    4.2.3 Pharmacological Classes
    Established Pharmacologic Class [EPC] - Vasodilator
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