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    Technical details about 03F36JH21U, learn more about the structure, uses, toxicity, action, side effects and more

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    03F36JH21U

    APIs // Active Pharmaceutical Ingredients

    PharmaCompass

    Minakem offers CDMO services for API & HPAPI, generics, regulatory expertise, track record performance & FDA & GMP certifications.

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    2D Structure
    Also known as: Ethylchlordiphene, 25287-60-9, Kitnos, Etofamide [inn], Eticlordifene, 2,2-dichloro-n-(2-ethoxyethyl)-n-[[4-(4-nitrophenoxy)phenyl]methyl]acetamide
    Molecular Formula
    C19H20Cl2N2O5
    Molecular Weight
    427.3  g/mol
    InChI Key
    QTRALMGDQMIVFF-UHFFFAOYSA-N
    FDA UNII
    03F36JH21U
    Etofamide is used as an antiamoebic agent. Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2,2-dichloro-N-(2-ethoxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl]acetamide
    2.1.2 InChI
    InChI=1S/C19H20Cl2N2O5/c1-2-27-12-11-22(19(24)18(20)21)13-14-3-7-16(8-4-14)28-17-9-5-15(6-10-17)23(25)26/h3-10,18H,2,11-13H2,1H3
    2.1.3 InChI Key
    QTRALMGDQMIVFF-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CCOCCN(CC1=CC=C(C=C1)OC2=CC=C(C=C2)[N+](=O)[O-])C(=O)C(Cl)Cl
    2.2 Other Identifiers
    2.2.1 UNII
    03F36JH21U
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Eticlordifene

    2. Etophamide

    3. Kitnos

    2.3.2 Depositor-Supplied Synonyms

    1. Ethylchlordiphene

    2. 25287-60-9

    3. Kitnos

    4. Etofamide [inn]

    5. Eticlordifene

    6. 2,2-dichloro-n-(2-ethoxyethyl)-n-[[4-(4-nitrophenoxy)phenyl]methyl]acetamide

    7. 03f36jh21u

    8. Etofamide (inn)

    9. Kitnosil

    10. 2,2-dichloro-n-(2-ethoxyethyl)-n-((p-nitrophenoxy)benzyl)-acetamide

    11. Chlorophenoxamide Ethyl Ether

    12. Etofamidum

    13. Etofamida

    14. Etofamidum [inn-latin]

    15. Etofamida [inn-spanish]

    16. Einecs 246-790-2

    17. Brn 2918322

    18. Unii-03f36jh21u

    19. K-430

    20. Kitnos (tn)

    21. 2,2-dichloro-n-(2-ethoxyethyl)-n-(p-(p-nitrophenoxy)benzyl)acetamide

    22. Etofamide [mart.]

    23. N-(2-etossietil)-n-(4-(4'-nitrofenossi)benzil)dicloroacetamide [italian]

    24. Etofamide [who-dd]

    25. Acetamide, 2,2-dichloro-n-(2-ethoxyethyl)-n-((4-(4-nitrophenoxy)phenyl)methyl)-

    26. Schembl1163863

    27. Chembl1788393

    28. Dtxsid40179926

    29. Chebi:135692

    30. N-(2-ethoxyethyl)-n-(p-(p-nitrophenoxy)-benzyl)dichloracetamide

    31. N-(2-etossietil)-n-(4-(4'-nitrofenossi)benzil)dicloroacetamide

    32. Zinc2019951

    33. Acetamide, 2,2-dichloro-n-(2-ethoxyethyl)-n-(p-(p-nitrophenoxy)benzyl)-

    34. Db13258

    35. D07355

    36. 287e609

    37. Q5404754

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 427.3 g/mol
    Molecular Formula C19H20Cl2N2O5
    XLogP34.1
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count9
    Exact Mass426.0749271 g/mol
    Monoisotopic Mass426.0749271 g/mol
    Topological Polar Surface Area84.6 Ų
    Heavy Atom Count28
    Formal Charge0
    Complexity487
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Amebicides

    Agents which are destructive to amebae, especially the parasitic species causing AMEBIASIS in man and animal. (See all compounds classified as Amebicides.)

    4.2 ATC Code

    P - Antiparasitic products, insecticides and repellents

    P01 - Antiprotozoals

    P01A - Agents against amoebiasis and other protozoal diseases

    P01AC - Dichloroacetamide derivatives

    P01AC03 - Etofamide

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