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    Technical details about 03C8I9296V, learn more about the structure, uses, toxicity, action, side effects and more

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    03C8I9296V

    APIs // Active Pharmaceutical Ingredients

    PharmaCompass

    Phyton is a World Leader in Plant Cell Fermentation Technology and Commercial Manufacturing.

    Athena Pharmaceutiques is a Partner of Choice for Drug Delivery & Life Cycle Management.

    2D Structure
    1. Also known as: 88069-49-2, Pilsicainide hcl, N-(2,6-dimethylphenyl)-2-(hexahydro-1h-pyrrolizin-7a-yl)acetamide hydrochloride, Sunrythm, Pilsicainide (hydrochloride), Sun 1165
    Molecular Formula
    C17H25ClN2O
    Molecular Weight
    308.8  g/mol
    InChI Key
    NZOSVDHCTCLGEB-UHFFFAOYSA-N
    FDA UNII
    03C8I9296V
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide;hydrochloride
    2.1.2 InChI
    InChI=1S/C17H24N2O.ClH/c1-13-6-3-7-14(2)16(13)18-15(20)12-17-8-4-10-19(17)11-5-9-17;/h3,6-7H,4-5,8-12H2,1-2H3,(H,18,20);1H
    2.1.3 InChI Key
    NZOSVDHCTCLGEB-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1=C(C(=CC=C1)C)NC(=O)CC23CCCN2CCC3.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    03C8I9296V
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 1h-pyrrolizine-7a(5h)-acetamide, N-(2,6-dimethylphenyl)tetrahydro-, Hydrochloride (1:1)

    2. 1h-pyrrolizine-7a(5h)-acetamide, N-(2,6-dimethylphenyl)tetrahydro-, Hydrochloride Hemihydrate

    3. N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide Hydrochloride

    4. Pilsicainide

    5. Pilsicainide Hydrochloride Hemihydrate

    6. Pilsicainide Hydrochloride Hydrate

    7. Sun 1165

    8. Sun-1165

    9. Tetrahydro-1h-pyrrolizine-7a(5h)-aceto-2',6'-xylidide

    2.3.2 Depositor-Supplied Synonyms

    1. 88069-49-2

    2. Pilsicainide Hcl

    3. N-(2,6-dimethylphenyl)-2-(hexahydro-1h-pyrrolizin-7a-yl)acetamide Hydrochloride

    4. Sunrythm

    5. Pilsicainide (hydrochloride)

    6. Sun 1165

    7. Pilsicainide Hydrochoride

    8. Sun 1165; Sunrythm

    9. 88069-49-2 (hcl)

    10. 03c8i9296v

    11. Sun-1165

    12. N-(2,6-dimethylphenyl)-2-(tetrahydro-1h-pyrrolizin-7a(5h)-yl)acetamide Hydrochloride

    13. N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide;hydrochloride

    14. Unii-03c8i9296v

    15. Pilsicainide Hydrochloride [jan]

    16. N-(2,6-dimethylphenyl)-1h-pyrrolizine-8-acetamide Hydrochloride

    17. N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide Monohydrochloride

    18. 1h-pyrrolizine-8-acetamide, Hexahydro-n-(2,6-dimethylphenyl)-, Hydrochloride

    19. N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide Hydrochloride

    20. Schembl483632

    21. Chembl4303511

    22. Dtxsid7057860

    23. Amy8863

    24. Bcp09636

    25. Mfcd00903769

    26. Akos025287418

    27. Ds-9555

    28. Du-6552

    29. 1h-pyrrolizine-7a(5h)-acetamide, N-(2,6-dimethylphenyl)tetrahydro-, Monohydrochloride

    30. Pilsicainide Hydrochloride [who-dd]

    31. Hy-101245

    32. Pilsicainide Hydrochloride, >=98% (hplc)

    33. Cs-0021031

    34. Ft-0630955

    35. P2634

    36. 69p492

    37. A16362

    38. C76901

    39. A842458

    40. Q27247552

    41. 1h-pyrrolizine-7a(5h)-acetamide, N-(2,6-dimethylphenyl)tetrahydro-, Hydrochloride (1:1)

    42. N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide,hydrochloride

    43. N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)ethanamide Hydrochloride

    44. N-(2,6-dimethylphenyl)-2-(hexahydro-1h-pyrrolizin-7a-yl)acetamide Hcl

    45. N-(2,6-dimethylphenyl)-2-(hexahydro-1h-pyrrolizin-7a-yl)acetamidehydrochloride

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 308.8 g/mol
    Molecular Formula C17H25ClN2O
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count3
    Exact Mass308.1655411 g/mol
    Monoisotopic Mass308.1655411 g/mol
    Topological Polar Surface Area32.3 Ų
    Heavy Atom Count21
    Formal Charge0
    Complexity348
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Arrhythmia Agents

    Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)

    Sodium Channel Blockers

    A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity. (See all compounds classified as Sodium Channel Blockers.)

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