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    Also known as: Tak-438, 1260141-27-2, 881681-01-2, Vonoprazan fumurate, 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1h-pyrrol-3-yl)-n-methylmethanamine fumarate, Tak 438
    Molecular Formula
    C21H20FN3O6S
    Molecular Weight
    461.5  g/mol
    InChI Key
    ROGSHYHKHPCCJW-WLHGVMLRSA-N
    FDA UNII
    4QW3X4AMLB
    Vonoprazan Fumarate
    Vonoprazan Fumarate is the fumarate salt form of vonoprazan, a pyrrole derivative and reversible potassium-competitive acid blocker (P-CAB), with potential antacid activity. Upon administration, vonoprazan specifically and competitively binds to the gastric hydrogen-potassium ATPase (H+/K+ ATPase) proton pump at or, more likely, near its potassium ion (K+) binding site and sterically inhibits K+ binding. This blocks the activation of the H+/K+ ATPase by K+, inhibits the proton pump and prevents gastric acid secretion, thereby lowering gastric acid levels.
    1 2D Structure

    Vonoprazan Fumarate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (E)-but-2-enedioic acid;1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine
    2.1.2 InChI
    InChI=1S/C17H16FN3O2S.C4H4O4/c1-19-10-13-9-17(15-6-2-3-7-16(15)18)21(12-13)24(22,23)14-5-4-8-20-11-14;5-3(6)1-2-4(7)8/h2-9,11-12,19H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
    2.1.3 InChI Key
    ROGSHYHKHPCCJW-WLHGVMLRSA-N
    2.1.4 Canonical SMILES
    CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=CC(=O)O)C(=O)O
    2.1.5 Isomeric SMILES
    CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=C/C(=O)O)\C(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    4QW3X4AMLB
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1h-pyrrol-3-yl)-n-methylmethanamine

    2. Tak 438

    3. Tak-438

    4. Tak438

    5. Vonoprazan

    2.3.2 Depositor-Supplied Synonyms

    1. Tak-438

    2. 1260141-27-2

    3. 881681-01-2

    4. Vonoprazan Fumurate

    5. 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1h-pyrrol-3-yl)-n-methylmethanamine Fumarate

    6. Tak 438

    7. Tak-438 Monofumarate

    8. Vonoprazan Monofumarate

    9. Vonoprazan Fumarate (tak-438)

    10. 4qw3x4amlb

    11. Tak438

    12. Unii-4qw3x4amlb

    13. Takecab

    14. Vocinti

    15. (e)-but-2-enedioic Acid;1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-n-methylmethanamine

    16. 1h-pyrrole-3-methanamine, 5-(2-fluorophenyl)-n-methyl-1-(3-pyridinylsulfonyl)-, (2e)-2-butenedioate (1:1)

    17. 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1h-pyrrol-3-yl)-n-methylmethanamine Xfumarate

    18. 1h-pyrrole-3-methanamine, 5-(2-fluorophenyl)-n-methyl-1-(3-pyridinylsulfonyl)-, 2-butenedioate (1:1)

    19. Mfcd18633280

    20. Vonoprazan Monofumurate

    21. 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1h-pyrrol-3-yl]-n-methylmethanamine Fumarate

    22. Takecab (tn)

    23. Vonoprazan Fumarate [usan]

    24. Schembl194394

    25. Schembl194396

    26. Chembl2064032

    27. Vonoprazan Fumarate [mi]

    28. Vonoprazan Fumarate (jan/usan)

    29. Ex-a097

    30. Vonoprazan Fumarate [jan]

    31. Bcp05635

    32. Bcp13238

    33. Ex-a4001

    34. S8016

    35. Vonoprazan Fumarate [who-dd]

    36. Akos027251052

    37. Ccg-269350

    38. 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1h-pyrrol-3-yl)-n-methylmethanamine Monofumarate

    39. 5-(2-fluorophenyl)-n-methyl-1-(3-pyridinylsulfonyl)-1h-pyrrole-3-methanamine (2e)-2-butenedioate

    40. Ac-29287

    41. Ac-29309

    42. Ds-12234

    43. Ls-14849

    44. Cs-0164592

    45. Sw220126-1

    46. D10466

    47. A854789

    48. A900258

    49. J-524312

    50. Q25104163

    51. Tak438 Fumarate;tak-438 Fumarate;tak 438 Fumarate;1260141-27-2

    52. 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1h-pyrrol-3-yl)-n-methylmethanamine Fumarate? (vonoprazan Impurity Pound(c)

    53. 2098974-13-9

    54. 5-(2-fluorophenyl)-n-methyl-1-(3-pyridinylsulfonyl)-1h-pyrrole-3-methanamine 2-butenedioate

    2.4 Create Date
    2010-05-17
    3 Chemical and Physical Properties
    Molecular Weight 461.5 g/mol
    Molecular Formula C21H20FN3O6S
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count9
    Rotatable Bond Count7
    Exact Mass461.10568470 g/mol
    Monoisotopic Mass461.10568470 g/mol
    Topological Polar Surface Area147 Ų
    Heavy Atom Count32
    Formal Charge0
    Complexity629
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count1
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2

    API Reference Price

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AP","supplier":"OPTIMUS DRUGS PRIVATE LTD","supplierCountry":"INDIA","foreign_port":"MONTEVIDEO -","customer":"UNDISCLOSED","customerCountry":"URUGUAY","quantity":"75.00","actualQuantity":"75","unit":"KGS","unitRateFc":"1200","totalValueFC":"87833.9","currency":"USD","unitRateINR":102495.90666666666,"date":"23-Aug-2025","totalValueINR":"7687193","totalValueInUsd":"87833.9","indian_port":"Hyderabad Air","hs_no":"29420022","bill_no":"4695704","productDescription":"API","marketType":"","country":"URUGUAY","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"PLOT NO.131,3RD FLOOR,NARMADA, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q3","strtotime":1756146600,"product":"VONOPRAZAN FUMARATE, BATCH NO-VPH-PU\/25004, MFG DT-APR-2025, RETEST DT-MAR-2028","address":"FLAT NO.302, BHANU ENCLAVE","city":"HYDERABAD.AP","supplier":"METROCHEM API PRIVATE LTD","supplierCountry":"INDIA","foreign_port":"BIRGUNJ","customer":"MAGNUS PHARMA PVT LTD","customerCountry":"NEPAL","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"35000","totalValueFC":"3999.1","currency":"N\/A","unitRateINR":35000,"date":"26-Aug-2025","totalValueINR":"350000","totalValueInUsd":"3999.1","indian_port":"Raxaul","hs_no":"29420090","bill_no":"4767577","productDescription":"API","marketType":"","country":"NEPAL","selfForZScoreResived":"Pharma Grade","supplierPort":"Raxaul","supplierAddress":"FLAT NO.302, BHANU ENCLAVE, HYDERABAD.AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q3","strtotime":1756319400,"product":"VONOPRAZAN FUMARATE","address":"8-3-166\/7\/1, HETERO HOUSE,","city":"HYDERABAD, AP.","supplier":"HONOUR LAB LTD","supplierCountry":"INDIA","foreign_port":"SINGAPORE","customer":"VARTIA PHARMA PTE LTD.","customerCountry":"SINGAPORE","quantity":"75.00","actualQuantity":"75","unit":"KGS","unitRateFc":"910","totalValueFC":"67005.7","currency":"USD","unitRateINR":78190.933333333334,"date":"28-Aug-2025","totalValueINR":"5864320","totalValueInUsd":"67005.7","indian_port":"Hyderabad Air","hs_no":"29349990","bill_no":"4805773","productDescription":"API","marketType":"","country":"SINGAPORE","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"8-3-166\/7\/1, HETERO HOUSE,, HYDERABAD, AP.","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1673807400,"product":"VONOPRAZAN FUMARATE","address":"811 THE SUMMIT BUSINESS BAY, NR W E,HIGHWAY METRO STATION, ANDHERI KU","city":"MUMBAI,MAHARASHTRA","supplier":"ZHEJIANG RUILIAN PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"NA","customer":"MEHTA API PRIVATE LTD","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"1500","totalValueFC":"1535.6","currency":"USD","unitRateINR":"125550","date":"16-Jan-2023","totalValueINR":"125550","totalValueInUsd":"1535.6","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"4201734","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"811 THE SUMMIT BUSINESS BAY, NR W E,HIGHWAY METRO STATION, ANDHERI KU"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1695234600,"product":"VONOPRAZAN FUMARATE","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"SHANDONG LONCOM PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"DR REDDY'S LABORATORIES","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"2700","totalValueFC":"2730.6","currency":"USD","unitRateINR":"226665","date":"21-Sep-2023","totalValueINR":"226665","totalValueInUsd":"2730.6","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"7925496","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"ADD: NO. 127, QIZHONG AVENUE, QIHECOUNTRY, DEZHOU, SHANDONG P.R. CHINA. China","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"}]
    25-Jan-2022
    28-Aug-2025
    KGS
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    Drugs in Development

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    • Deals
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    Virtual BoothEvonik's CDMO solutions for APIs and HPAPIs: It specializes where the client needs it most!

    Evonik and Phathom Pharmaceuticals Partner to Produce Novel Acid-Blocker Vonoprazan

    Details:

    Vonoprazan is a novel potassium-competitive acid blocker (PCAB). It inhibits gastric acid secretion by acting as a reversible competitive inhibitor against potassium ions.


    Lead Product(s): Vonoprazan Fumarate,Amoxicillin Trihydrate,Clarithromycin

    Therapeutic Area: Infections and Infectious Diseases Brand Name: Voquezna Triple Pack

    Study Phase: Approved FDFProduct Type: Miscellaneous

    Sponsor: Phathom Pharmaceuticals

    Deal Size: Undisclosed Upfront Cash: Undisclosed

    Deal Type: Agreement October 24, 2022

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    01

    Evonik

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    Booth #5.1A24
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    Virtual BoothEvonik's CDMO solutions for APIs and HPAPIs: It specializes where the client needs it most!

    Lead Product(s) : Vonoprazan Fumarate,Amoxicillin Trihydrate,Clarithromycin

    Therapeutic Area : Infections and Infectious Diseases

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Phathom Pharmaceuticals

    Deal Size : Undisclosed

    Deal Type : Agreement

    DEALS_DEV arrow-down

    Evonik and Phathom Pharmaceuticals Partner to Produce Novel Acid-Blocker Vonoprazan

    Details : Vonoprazan is a novel potassium-competitive acid blocker (PCAB). It inhibits gastric acid secretion by acting as a reversible competitive inhibitor against potassium ions.

    Product Name : Voquezna Triple Pack

    Product Type : Miscellaneous

    Upfront Cash : Undisclosed

    October 24, 2022

    Evonik company banner

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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

    Phathom Gets FDA Nod for 10 Years of Regulatory Exclusivity for Voquezna

    Details:

    Voquezna (vonoprazan) is a potassium-competitive acid blocker, indicated for heartburn associated with Non-Erosive GERD.


    Lead Product(s): Vonoprazan Fumarate,Inapplicable

    Therapeutic Area: Gastroenterology Brand Name: Voquezna

    Study Phase: Approved FDFProduct Type: Miscellaneous

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable June 06, 2025

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    02

    Phathom Pharmaceuticals

    U.S.A
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    Not Confirmed

    Phathom Pharmaceuticals

    U.S.A
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    PREP
    Not Confirmed
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    Lead Product(s) : Vonoprazan Fumarate,Inapplicable

    Therapeutic Area : Gastroenterology

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Phathom Gets FDA Nod for 10 Years of Regulatory Exclusivity for Voquezna

    Details : Voquezna (vonoprazan) is a potassium-competitive acid blocker, indicated for heartburn associated with Non-Erosive GERD.

    Product Name : Voquezna

    Product Type : Miscellaneous

    Upfront Cash : Inapplicable

    June 06, 2025

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    A Study in Adult and Adolescent Participants With EoE to Evaluate Vonoprazan 10 mg and 20 mg Compared to Placebo After 12 Weeks and to Evaluate Vonopraz...

    Details:

    Vonoprazan is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Eosinophilic Esophagitis.


    Lead Product(s): Vonoprazan Fumarate,Inapplicable

    Therapeutic Area: Gastroenterology Brand Name: Undisclosed

    Study Phase: Phase IIProduct Type: Miscellaneous

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable February 28, 2025

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    03

    Phathom Pharmaceuticals

    U.S.A
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    PREP
    Not Confirmed

    Phathom Pharmaceuticals

    U.S.A
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    PREP
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    Lead Product(s) : Vonoprazan Fumarate,Inapplicable

    Therapeutic Area : Gastroenterology

    Highest Development Status : Phase II

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    A Study in Adult and Adolescent Participants With EoE to Evaluate Vonoprazan 10 mg and 20 mg Compa...

    Details : Vonoprazan is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Eosinophilic Esophagitis.

    Product Name : Undisclosed

    Product Type : Miscellaneous

    Upfront Cash : Inapplicable

    February 28, 2025

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    A Study to Evaluate Two Vonoprazan Orally Disintegrating Tablet Formulations Administered Without Water or Mixed With Water and Administered Via a Syrin...

    Details:

    Vonoprazan is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.


    Lead Product(s): Vonoprazan Fumarate,Inapplicable

    Therapeutic Area: Undisclosed Brand Name: Undisclosed

    Study Phase: Phase IProduct Type: Miscellaneous

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable February 18, 2025

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    04

    Phathom Pharmaceuticals

    U.S.A
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    PREP
    Not Confirmed

    Phathom Pharmaceuticals

    U.S.A
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    PREP
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    Lead Product(s) : Vonoprazan Fumarate,Inapplicable

    Therapeutic Area : Undisclosed

    Highest Development Status : Phase I

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    A Study to Evaluate Two Vonoprazan Orally Disintegrating Tablet Formulations Administered Without ...

    Details : Vonoprazan is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

    Product Name : Undisclosed

    Product Type : Miscellaneous

    Upfront Cash : Inapplicable

    February 18, 2025

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    Study to Evaluate the Bioequivalence of Vonopzan Tablet 20mg(Vonoprazan Fumarate) and Vocinti Tablet 20mg in Healthy Adult Subjects.

    Details:

    Vonoprazan is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Stomach Ulcer.


    Lead Product(s): Vonoprazan Fumarate,Inapplicable

    Therapeutic Area: Gastroenterology Brand Name: Undisclosed

    Study Phase: Phase IProduct Type: Miscellaneous

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable October 15, 2024

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    05

    Hanlim Pharmaceuticals Inc

    South Korea
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    Not Confirmed

    Hanlim Pharmaceuticals Inc

    South Korea
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    PREP
    Not Confirmed
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

    Lead Product(s) : Vonoprazan Fumarate,Inapplicable

    Therapeutic Area : Gastroenterology

    Highest Development Status : Phase I

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Study to Evaluate the Bioequivalence of Vonopzan Tablet 20mg(Vonoprazan Fumarate) and Vocinti Tabl...

    Details : Vonoprazan is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Stomach Ulcer.

    Product Name : Undisclosed

    Product Type : Miscellaneous

    Upfront Cash : Inapplicable

    October 15, 2024

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    Lupin Partners with Takeda to Commercialise Vonoprazan

    Details:

    Under the terms of this agreement, Takeda has granted Lupin non-exclusive patent licensing rights to commercialize Lupivon (vonoprazan), a novel potassium-competitive acid blocker, in India.


    Lead Product(s): Vonoprazan Fumarate,Inapplicable

    Therapeutic Area: Gastroenterology Brand Name: Lupivon

    Study Phase: Approved FDFProduct Type: Miscellaneous

    Sponsor: Lupin Ltd

    Deal Size: Undisclosed Upfront Cash: Undisclosed

    Deal Type: Licensing Agreement September 18, 2024

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    06

    Takeda Pharmaceutical

    Japan
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    PREP
    Not Confirmed

    Takeda Pharmaceutical

    Japan
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    PREP
    Not Confirmed
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    Lead Product(s) : Vonoprazan Fumarate,Inapplicable

    Therapeutic Area : Gastroenterology

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Lupin Ltd

    Deal Size : Undisclosed

    Deal Type : Licensing Agreement

    DEALS_DEV arrow-down

    Lupin Partners with Takeda to Commercialise Vonoprazan

    Details : Under the terms of this agreement, Takeda has granted Lupin non-exclusive patent licensing rights to commercialize Lupivon (vonoprazan), a novel potassium-competitive acid blocker, in India.

    Product Name : Lupivon

    Product Type : Miscellaneous

    Upfront Cash : Undisclosed

    September 18, 2024

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    Alkem Inks Licensing Pact with Takeda to Introduce Vonoprazan in India

    Details:

    The licensing deal will enhance Alkem's offerings in the gastrointestinal segment by including Vonzai (vonoprazan), a first-in-class potassium-competitive acid blocker.


    Lead Product(s): Vonoprazan Fumarate,Inapplicable

    Therapeutic Area: Gastroenterology Brand Name: Vonzai

    Study Phase: Approved FDFProduct Type: Miscellaneous

    Sponsor: Alkem Laboratories

    Deal Size: Undisclosed Upfront Cash: Undisclosed

    Deal Type: Licensing Agreement September 03, 2024

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    07

    Takeda Pharmaceutical

    Japan
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    Not Confirmed

    Takeda Pharmaceutical

    Japan
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    PREP
    Not Confirmed
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    Lead Product(s) : Vonoprazan Fumarate,Inapplicable

    Therapeutic Area : Gastroenterology

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Alkem Laboratories

    Deal Size : Undisclosed

    Deal Type : Licensing Agreement

    DEALS_DEV arrow-down

    Alkem Inks Licensing Pact with Takeda to Introduce Vonoprazan in India

    Details : The licensing deal will enhance Alkem's offerings in the gastrointestinal segment by including Vonzai (vonoprazan), a first-in-class potassium-competitive acid blocker.

    Product Name : Vonzai

    Product Type : Miscellaneous

    Upfront Cash : Undisclosed

    September 03, 2024

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    Phathom Pharmaceuticals Prices $130M Offering of Common Stock, Pre-Funded Warrants

    Details:

    Phathom intends to use the net proceeds from the offering to fund commercialization expenses and further clinical development of Voquezna (vonoprazan) for the treatment of Erosive GERD.


    Lead Product(s): Vonoprazan Fumarate,Inapplicable

    Therapeutic Area: Gastroenterology Brand Name: Voquezna

    Study Phase: Approved FDFProduct Type: Miscellaneous

    Sponsor: Evercore ISI

    Deal Size: $130.0 million Upfront Cash: Undisclosed

    Deal Type: Public Offering August 19, 2024

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    08

    Phathom Pharmaceuticals

    U.S.A
    arrow
    PREP
    Not Confirmed

    Phathom Pharmaceuticals

    U.S.A
    arrow
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    Lead Product(s) : Vonoprazan Fumarate,Inapplicable

    Therapeutic Area : Gastroenterology

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Evercore ISI

    Deal Size : $130.0 million

    Deal Type : Public Offering

    DEALS_DEV arrow-down

    Phathom Pharmaceuticals Prices $130M Offering of Common Stock, Pre-Funded Warrants

    Details : Phathom intends to use the net proceeds from the offering to fund commercialization expenses and further clinical development of Voquezna (vonoprazan) for the treatment of Erosive GERD.

    Product Name : Voquezna

    Product Type : Miscellaneous

    Upfront Cash : Undisclosed

    August 19, 2024

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    Zydus signs patent licensing agreement with Takeda for 'VaultA’ in India

    Details:

    Under the terms of this agreement, Takeda has granted Zydus non-exclusive patent licensing rights for the commercialization of Vault (vonoprazan) in India.


    Lead Product(s): Vonoprazan Fumarate,Inapplicable

    Therapeutic Area: Gastroenterology Brand Name: Vault

    Study Phase: Approved FDFProduct Type: Miscellaneous

    Sponsor: Zydus Lifesciences

    Deal Size: Undisclosed Upfront Cash: Undisclosed

    Deal Type: Licensing Agreement July 19, 2024

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    09

    Takeda Pharmaceutical

    Japan
    arrow
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    Not Confirmed

    Takeda Pharmaceutical

    Japan
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    Not Confirmed
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    Lead Product(s) : Vonoprazan Fumarate,Inapplicable

    Therapeutic Area : Gastroenterology

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Zydus Lifesciences

    Deal Size : Undisclosed

    Deal Type : Licensing Agreement

    DEALS_DEV arrow-down

    Zydus signs patent licensing agreement with Takeda for 'VaultA’ in India

    Details : Under the terms of this agreement, Takeda has granted Zydus non-exclusive patent licensing rights for the commercialization of Vault (vonoprazan) in India.

    Product Name : Vault

    Product Type : Miscellaneous

    Upfront Cash : Undisclosed

    July 19, 2024

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    Dr. Reddy's Signs Patent Licensing Agreement with Takeda to Commercialize Vonoprazan

    Details:

    Under the terms of this agreement, Takeda has granted Reddy non-exclusive patent licensing rights for the commercialization of Voquezna (vonoprazan) in India.


    Lead Product(s): Vonoprazan Fumarate,Inapplicable

    Therapeutic Area: Gastroenterology Brand Name: Vault

    Study Phase: Approved FDFProduct Type: Miscellaneous

    Sponsor: Dr. Reddy\'s Laboratories

    Deal Size: Undisclosed Upfront Cash: Undisclosed

    Deal Type: Licensing Agreement July 18, 2024

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    10

    Takeda Pharmaceutical

    Japan
    arrow
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    Not Confirmed

    Takeda Pharmaceutical

    Japan
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    Not Confirmed
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    Lead Product(s) : Vonoprazan Fumarate,Inapplicable

    Therapeutic Area : Gastroenterology

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Dr. Reddy\'s Laboratories

    Deal Size : Undisclosed

    Deal Type : Licensing Agreement

    DEALS_DEV arrow-down

    Dr. Reddy's Signs Patent Licensing Agreement with Takeda to Commercialize Vonoprazan

    Details : Under the terms of this agreement, Takeda has granted Reddy non-exclusive patent licensing rights for the commercialization of Voquezna (vonoprazan) in India.

    Product Name : Vault

    Product Type : Miscellaneous

    Upfront Cash : Undisclosed

    July 18, 2024

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    INTERMEDIATE SUPPLIERS

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    01

    Shandong Chenghui Shuangda Pharmace...

    China
    CPhI WW Frankfurt
    Booth #12.0F108
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    Virtual BoothChina's leading API and intermediate manufacturer, offering CMO/CDMO services and exports to 70+ countries, enhancing global health.

    5-(2-fluorophenyl)-1H-pyrrole-3- carbonitrile

    CAS Number : 1240948-77-9

    End Use API : Vonoprazan Fumarate

    About The Company : Shandong Chenghui Shuangda Pharmaceutical Co., Ltd. specializes in R&D and production of APIs and advanced intermediates, CDMO/CRO/OEM, and Technology Transfer ...

    Shandong Chenghui Shuangda Pharmaceutical

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    02

    Shandong Chenghui Shuangda Pharmace...

    China
    CPhI WW Frankfurt
    Booth #12.0F108
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    Virtual BoothChina's leading API and intermediate manufacturer, offering CMO/CDMO services and exports to 70+ countries, enhancing global health.

    5-(2-fluorophenyl)-1H-Pyrrole-3- carboxaldehyde

    CAS Number : 881674-56-2

    End Use API : Vonoprazan Fumarate

    About The Company : Shandong Chenghui Shuangda Pharmaceutical Co., Ltd. specializes in R&D and production of APIs and advanced intermediates, CDMO/CRO/OEM, and Technology Transfer ...

    Shandong Chenghui Shuangda Pharmaceutical

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    03

    Shandong Chenghui Shuangda Pharmace...

    China
    CPhI WW Frankfurt
    Booth #12.0F108
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    Virtual BoothChina's leading API and intermediate manufacturer, offering CMO/CDMO services and exports to 70+ countries, enhancing global health.

    Pyridine-3-sulfonyl chloride hydrochloride

    CAS Number : 16133-25-8

    End Use API : Vonoprazan Fumarate

    About The Company : Shandong Chenghui Shuangda Pharmaceutical Co., Ltd. specializes in R&D and production of APIs and advanced intermediates, CDMO/CRO/OEM, and Technology Transfer ...

    Shandong Chenghui Shuangda Pharmaceutical

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    04

    Jinan Tantu Chemicals

    China
    PREP
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    Virtual BoothJinan Tantu Chemicals offers customized R&D services & production of small molecule APIs & pharmaceutical intermediates.

    Pyridine-3-Sulfonyl Chloride Hydrochloride

    CAS Number : 16133-25-8

    End Use API : Vonoprazan Fumarate

    About The Company : Jinan Tantu Chemicals Co., Ltd. operates as a Contract Development and Manufacturing Organization (CDMO) that serves pharmaceutical companies worldwide. Our cor...

    Jinan Tantu Chemicals

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    05

    Shandong Loncom Pharmaceutical

    China
    CPhI WW Frankfurt
    Attending
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    Virtual BoothShandong Loncom is an R&D-focused manufacturer of Anti-cancer APIs.

    5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde

    CAS Number : 881674-56-2

    End Use API : Vonoprazan Fumarate

    About The Company : Established in May 2012, Shandong Loncom Pharmaceutical operates as a fully owned subsidiary of Shandong Bestcomm Pharmaceutical Co., Ltd. Situated in the Qihe ...

    Shandong Loncom Pharmaceutical company banner

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    06

    Shandong Loncom Pharmaceutical

    China
    CPhI WW Frankfurt
    Attending
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    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothShandong Loncom is an R&D-focused manufacturer of Anti-cancer APIs.

    Pyridine-3-sulfonyl chloride

    CAS Number : 16133-25-8

    End Use API : Vonoprazan Fumarate

    About The Company : Established in May 2012, Shandong Loncom Pharmaceutical operates as a fully owned subsidiary of Shandong Bestcomm Pharmaceutical Co., Ltd. Situated in the Qihe ...

    Shandong Loncom Pharmaceutical company banner

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    07

    Shandong Loncom Pharmaceutical

    China
    CPhI WW Frankfurt
    Attending
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    • WHO-GMP

    Virtual BoothShandong Loncom is an R&D-focused manufacturer of Anti-cancer APIs.

    5-(2-Fluorophenyl)-1-(pyridine-3-sulfonyl)-1H- pyr...

    CAS Number : 807-719-6

    End Use API : Vonoprazan Fumarate

    About The Company : Established in May 2012, Shandong Loncom Pharmaceutical operates as a fully owned subsidiary of Shandong Bestcomm Pharmaceutical Co., Ltd. Situated in the Qihe ...

    Shandong Loncom Pharmaceutical company banner

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    08

    Shanghai Minbiotech

    China
    CPhI WW Frankfurt
    Attending
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    Virtual BoothShanghai Minbiotech is the leading producer of biopharmaceuticals and a variety of high-end generic & innovative drugs.

    3-Pyridinesulfonyl chloride

    CAS Number : 16133-25-8

    End Use API : Vonoprazan Fumarate

    About The Company : ​Headquartered in Fengxian District, Shanghai Minbiotech Co., Ltd. is a company specializing in the R&D and production of advanced pharmaceutical intermediate...

    Shanghai Minbiotech CB

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    09

    Shanghai Minbiotech

    China
    CPhI WW Frankfurt
    Attending
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    • EDQM
    • WHO-GMP

    Virtual BoothShanghai Minbiotech is the leading producer of biopharmaceuticals and a variety of high-end generic & innovative drugs.

    5-(2-fluorophenyl)-1H- Pyrrole-3-carboxaldehyde

    CAS Number : 881674-56-2

    End Use API : Vonoprazan Fumarate

    About The Company : ​Headquartered in Fengxian District, Shanghai Minbiotech Co., Ltd. is a company specializing in the R&D and production of advanced pharmaceutical intermediate...

    Shanghai Minbiotech CB

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    10

    Tagoor Laboratories

    India
    CPhI WW Frankfurt
    Booth #12.1B84
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    Virtual BoothTagoor's product development expertise, backed by our comprehensive understanding of the processes, helps us offer high-quality APIs.

    5-(2-Fluorophenyl)-1H-pyrrole-3-carboxaldehyde

    CAS Number : 881674-56-2

    End Use API : Vonoprazan Fumarate

    About The Company : Tagoor Laboratories, established in 2018, is a part of the Tagoor Group. It specializes in providing APIs, advanced intermediates and key starting materials for...

    Tagoor Laboratories

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    FDF Dossiers

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    01

    Al Esraa Pharmaceuticals

    Egypt
    PREP
    Not Confirmed
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    Al Esraa Pharmaceuticals

    Egypt
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    Flag Egypt
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Egypt

    Vonoprazan

    Brand Name : Vonacidan

    Dosage Form : Film-Coated Tablet

    Dosage Strength : 10MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Egypt

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    02

    Al Esraa Pharmaceuticals

    Egypt
    PREP
    Not Confirmed
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    Al Esraa Pharmaceuticals

    Egypt
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    PREP
    Not Confirmed
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    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Egypt

    Vonoprazan

    Brand Name : Vonacidan

    Dosage Form : Film-Coated Tablet

    Dosage Strength : 20MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Egypt

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    03

    EP Pharma

    Egypt
    PREP
    Not Confirmed
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    EP Pharma

    Egypt
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    PREP
    Not Confirmed
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    Flag Egypt
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Egypt

    Vonoprazan

    Brand Name : Arromaprazan

    Dosage Form : FC Tablet

    Dosage Strength : 20MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Egypt

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    04

    EP Pharma

    Egypt
    PREP
    Not Confirmed
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    EP Pharma

    Egypt
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    Not Confirmed
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    Flag Egypt
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Egypt

    Vonoprazan

    Brand Name : Arromaprazan

    Dosage Form : FC Tablet

    Dosage Strength : 10MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Egypt

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    05

    Hochster Pharmaceutical Industries

    Egypt
    PREP
    Not Confirmed
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    Hochster Pharmaceutical Industries

    Egypt
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    PREP
    Not Confirmed
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    Virtual Booth Virtual Booth
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    Regulatory Info :

    Registration Country : Egypt

    Vonoprazan

    Brand Name : Leurovendin

    Dosage Form : Film Coated Tablet

    Dosage Strength : 20MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Egypt

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    06

    Phathom Pharmaceuticals

    U.S.A
    PREP
    Not Confirmed
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    Phathom Pharmaceuticals

    U.S.A
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    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : RX

    Registration Country : USA

    VONOPRAZAN FUMARATE

    Brand Name : VOQUEZNA

    Dosage Form : TABLET;ORAL

    Dosage Strength : EQ 10MG BASE

    Packaging :

    Approval Date : 2023-11-01

    Application Number : 215151

    Regulatory Info : RX

    Registration Country : USA

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    07

    Phathom Pharmaceuticals

    U.S.A
    PREP
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    Phathom Pharmaceuticals

    U.S.A
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    Virtual Booth Virtual Booth
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    Regulatory Info : RX

    Registration Country : USA

    VONOPRAZAN FUMARATE

    Brand Name : VOQUEZNA

    Dosage Form : TABLET;ORAL

    Dosage Strength : EQ 20MG BASE

    Packaging :

    Approval Date : 2023-11-01

    Application Number : 215151

    Regulatory Info : RX

    Registration Country : USA

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    08

    Phathom Pharmaceuticals

    U.S.A
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    Virtual Booth Virtual Booth
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    Regulatory Info :

    Registration Country : USA

    VONOPRAZAN FUMARATE

    Brand Name : VOQUEZNA

    Dosage Form : TABLET; ORAL

    Dosage Strength : EQ 10MG BASE

    Packaging :

    Approval Date :

    Application Number : 218710

    Regulatory Info :

    Registration Country : USA

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    Phathom Pharmaceuticals

    U.S.A
    PREP
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    U.S.A
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    Virtual Booth Virtual Booth
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    Regulatory Info :

    Registration Country : USA

    VONOPRAZAN FUMARATE

    Brand Name : VOQUEZNA

    Dosage Form : TABLET; ORAL

    Dosage Strength : EQ 20MG BASE

    Packaging :

    Approval Date :

    Application Number : 218710

    Regulatory Info :

    Registration Country : USA

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    10

    Utopia

    Egypt
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    Utopia

    Egypt
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    Regulatory Info :

    Registration Country : Egypt

    Vonoprazan

    Brand Name : Vonopravin

    Dosage Form : Film Coated Tablet

    Dosage Strength : 10MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Egypt

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    FDA Orange Book

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    01

    PHATHOM

    U.S.A
    PREP
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    PHATHOM

    U.S.A
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    RLD : Yes

    TE Code :

    VONOPRAZAN FUMARATE

    Brand Name : VOQUEZNA

    Dosage Form : TABLET;ORAL

    Dosage Strength : EQ 10MG BASE

    Approval Date : 2023-11-01

    Application Number : 215151

    RX/OTC/DISCN : RX

    RLD : Yes

    TE Code :

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    PHATHOM

    U.S.A
    PREP
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    PHATHOM

    U.S.A
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    RLD : Yes

    TE Code :

    VONOPRAZAN FUMARATE

    Brand Name : VOQUEZNA

    Dosage Form : TABLET;ORAL

    Dosage Strength : EQ 20MG BASE

    Approval Date : 2023-11-01

    Application Number : 215151

    RX/OTC/DISCN : RX

    RLD : Yes

    TE Code :

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    PHATHOM PHARMACEUTICALS INC

    U.S.A
    PREP
    Not Confirmed
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    PHATHOM PHARMACEUTICALS INC

    U.S.A
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    RLD :

    TE Code :

    VONOPRAZAN FUMARATE

    Brand Name : VOQUEZNA

    Dosage Form : TABLET; ORAL

    Dosage Strength : EQ 10MG BASE

    Approval Date :

    Application Number : 218710

    RX/OTC/DISCN :

    RLD :

    TE Code :

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    PHATHOM PHARMACEUTICALS INC

    U.S.A
    PREP
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    PHATHOM PHARMACEUTICALS INC

    U.S.A
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    Patent Expiration Date : 2030-08-11

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    US Patent Number : 9186411

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    Patent Expiration Date : 2028-08-11

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    US Patent Number : 7977488

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    US Patent Number : 7977488

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    Application Number : 215151

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    US Patent Number : 9186411

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      I-948
      2027-07-17
      215151
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        2027-05-03
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                  ABOUT THIS PAGE

                  Looking for 1260141-27-2 / Vonoprazan Fumarate API manufacturers, exporters & distributors?

                  Vonoprazan Fumarate manufacturers, exporters & distributors 1

                  36

                  PharmaCompass offers a list of Vonoprazan Fumarate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Vonoprazan Fumarate manufacturer or Vonoprazan Fumarate supplier for your needs.

                  Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Vonoprazan Fumarate manufacturer or Vonoprazan Fumarate supplier.

                  PharmaCompass also assists you with knowing the Vonoprazan Fumarate API Price utilized in the formulation of products. Vonoprazan Fumarate API Price is not always fixed or binding as the Vonoprazan Fumarate Price is obtained through a variety of data sources. The Vonoprazan Fumarate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

                  API | Excipient name

                  Vonoprazan Fumarate

                  Synonyms

                  Tak-438, 1260141-27-2, 881681-01-2, Vonoprazan fumurate, 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1h-pyrrol-3-yl)-n-methylmethanamine fumarate, Tak 438

                  Cas Number

                  1260141-27-2

                  Unique Ingredient Identifier (UNII)

                  4QW3X4AMLB

                  About Vonoprazan Fumarate

                  Vonoprazan Fumarate is the fumarate salt form of vonoprazan, a pyrrole derivative and reversible potassium-competitive acid blocker (P-CAB), with potential antacid activity. Upon administration, vonoprazan specifically and competitively binds to the gastric hydrogen-potassium ATPase (H+/K+ ATPase) proton pump at or, more likely, near its potassium ion (K+) binding site and sterically inhibits K+ binding. This blocks the activation of the H+/K+ ATPase by K+, inhibits the proton pump and prevents gastric acid secretion, thereby lowering gastric acid levels.

                  Vonoprazan Fumarate Manufacturers

                  A Vonoprazan Fumarate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Vonoprazan Fumarate, including repackagers and relabelers. The FDA regulates Vonoprazan Fumarate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Vonoprazan Fumarate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

                  click here to find a list of Vonoprazan Fumarate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

                  Vonoprazan Fumarate Suppliers

                  A Vonoprazan Fumarate supplier is an individual or a company that provides Vonoprazan Fumarate active pharmaceutical ingredient (API) or Vonoprazan Fumarate finished formulations upon request. The Vonoprazan Fumarate suppliers may include Vonoprazan Fumarate API manufacturers, exporters, distributors and traders.

                  click here to find a list of Vonoprazan Fumarate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

                  Vonoprazan Fumarate USDMF

                  A Vonoprazan Fumarate DMF (Drug Master File) is a document detailing the whole manufacturing process of Vonoprazan Fumarate active pharmaceutical ingredient (API) in detail. Different forms of Vonoprazan Fumarate DMFs exist exist since differing nations have different regulations, such as Vonoprazan Fumarate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

                  A Vonoprazan Fumarate DMF submitted to regulatory agencies in the US is known as a USDMF. Vonoprazan Fumarate USDMF includes data on Vonoprazan Fumarate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Vonoprazan Fumarate USDMF is kept confidential to protect the manufacturer’s intellectual property.

                  click here to find a list of Vonoprazan Fumarate suppliers with USDMF on PharmaCompass.

                  Vonoprazan Fumarate KDMF

                  In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

                  Pharmaceutical companies submit a Vonoprazan Fumarate Drug Master File in Korea (Vonoprazan Fumarate KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Vonoprazan Fumarate. The MFDS reviews the Vonoprazan Fumarate KDMF as part of the drug registration process and uses the information provided in the Vonoprazan Fumarate KDMF to evaluate the safety and efficacy of the drug.

                  After submitting a Vonoprazan Fumarate KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Vonoprazan Fumarate API can apply through the Korea Drug Master File (KDMF).

                  click here to find a list of Vonoprazan Fumarate suppliers with KDMF on PharmaCompass.

                  Vonoprazan Fumarate WC

                  A Vonoprazan Fumarate written confirmation (Vonoprazan Fumarate WC) is an official document issued by a regulatory agency to a Vonoprazan Fumarate manufacturer, verifying that the manufacturing facility of a Vonoprazan Fumarate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Vonoprazan Fumarate APIs or Vonoprazan Fumarate finished pharmaceutical products to another nation, regulatory agencies frequently require a Vonoprazan Fumarate WC (written confirmation) as part of the regulatory process.

                  click here to find a list of Vonoprazan Fumarate suppliers with Written Confirmation (WC) on PharmaCompass.

                  Vonoprazan Fumarate NDC

                  National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Vonoprazan Fumarate as an active pharmaceutical ingredient (API).

                  Finished drug products

                  The FDA updates the NDC directory daily. The NDC numbers for Vonoprazan Fumarate API and other APIs are published in this directory by the FDA.

                  Unfinished drugs

                  The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

                  Pharmaceutical companies that manufacture Vonoprazan Fumarate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

                  Compounded drug products

                  The NDC directory also contains data on finished compounded human drug products that contain Vonoprazan Fumarate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Vonoprazan Fumarate NDC to their finished compounded human drug products, they may choose to do so.

                  click here to find a list of Vonoprazan Fumarate suppliers with NDC on PharmaCompass.

                  Vonoprazan Fumarate GMP

                  Vonoprazan Fumarate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

                  GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

                  PharmaCompass offers a list of Vonoprazan Fumarate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Vonoprazan Fumarate GMP manufacturer or Vonoprazan Fumarate GMP API supplier for your needs.

                  Vonoprazan Fumarate CoA

                  A Vonoprazan Fumarate CoA (Certificate of Analysis) is a formal document that attests to Vonoprazan Fumarate's compliance with Vonoprazan Fumarate specifications and serves as a tool for batch-level quality control.

                  Vonoprazan Fumarate CoA mostly includes findings from lab analyses of a specific batch. For each Vonoprazan Fumarate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

                  Vonoprazan Fumarate may be tested according to a variety of international standards, such as European Pharmacopoeia (Vonoprazan Fumarate EP), Vonoprazan Fumarate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Vonoprazan Fumarate USP).

                  Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
                  For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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