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Chemistry

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Also known as: Bricanyl, Terbutaline hemisulfate, Tert-butyl-[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]azanium;sulfate, Bricanyl turbuhaler, 576pu70y8e, 1,3-benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-, sulfate (2:1) (salt)
Molecular Formula
C24H40N2O10S
Molecular Weight
548.6  g/mol
InChI Key
KFVSLSTULZVNPG-UHFFFAOYSA-N

Terbutaline Sulphate
A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.
1 2D Structure

Terbutaline Sulphate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
tert-butyl-[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]azanium;sulfate
2.1.2 InChI
InChI=1S/2C12H19NO3.H2O4S/c2*1-12(2,3)13-7-11(16)8-4-9(14)6-10(15)5-8;1-5(2,3)4/h2*4-6,11,13-16H,7H2,1-3H3;(H2,1,2,3,4)
2.1.3 InChI Key
KFVSLSTULZVNPG-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(C)(C)[NH2+]CC(C1=CC(=CC(=C1)O)O)O.CC(C)(C)[NH2+]CC(C1=CC(=CC(=C1)O)O)O.[O-]S(=O)(=O)[O-]
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Arubendol

2. Asthmoprotect

3. Brethine

4. Bricanyl

5. Bricanyl Sa

6. Butaliret

7. Butalitab

8. Contimit

9. Kwd 2019

10. Kwd-2019

11. Kwd2019

12. Monovent

13. Taziken

14. Tedipulmo

15. Terbasmin

16. Terbul

17. Terbutalin Al

18. Terbutalin Ratiopharm

19. Terbutalin Stada

20. Terbutalin Von Ct

21. Terbutalin-ratiopharm

22. Terbutaline

23. Terbutaline Sulfate

24. Terbuturmant

2.2.2 Depositor-Supplied Synonyms

1. Bricanyl

2. Terbutaline Hemisulfate

3. Tert-butyl-[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]azanium;sulfate

4. Bricanyl Turbuhaler

5. 576pu70y8e

6. 1,3-benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-, Sulfate (2:1) (salt)

7. Einecs 245-386-3

8. Unii-576pu70y8e

9. 1-(3,5-dihydroxyphenyl)-2-tert-butylaminoethanol Sulphate

10. Terbutaline Sulfate [usan:usp:jan]

11. Nsc 757336

12. (+-)-alpha-((tert-butylamino)methyl)-3,5-dihydroxybenzyl Alcohol Sulfate (2:1) (salt)

13. Benzyl Alcohol, Alpha-((tert-butylamino)methyl)-3,5-dihydroxy-, Sulfate (2:1)

2.3 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 548.6 g/mol
Molecular Formula C24H40N2O10S
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count10
Rotatable Bond Count8
Exact Mass548.24036665 g/mol
Monoisotopic Mass548.24036665 g/mol
Topological Polar Surface Area243 Ų
Heavy Atom Count37
Formal Charge0
Complexity267
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameTerbutaline sulfate
Drug LabelTerbutaline Sulfate, USP, the active ingredient of Terbutaline Sulfate Injection, USP, is a betaadrenergic agonist bronchodilator available as a sterile, nonpyrogenic, aqueous solution in vials, for subcutaneous administration. Each milliliter of...
Active IngredientTerbutaline sulfate
Dosage FormTablet; Injectable
RouteInjection; Oral
Strength2.5mg; 1mg/ml; 5mg
Market StatusPrescription
CompanyBedford; Hikma Farmaceutica; United Biomedcl; Fresenius Kabi Usa; Lannett; Impax Labs; Akorn

2 of 2  
Drug NameTerbutaline sulfate
Drug LabelTerbutaline Sulfate, USP, the active ingredient of Terbutaline Sulfate Injection, USP, is a betaadrenergic agonist bronchodilator available as a sterile, nonpyrogenic, aqueous solution in vials, for subcutaneous administration. Each milliliter of...
Active IngredientTerbutaline sulfate
Dosage FormTablet; Injectable
RouteInjection; Oral
Strength2.5mg; 1mg/ml; 5mg
Market StatusPrescription
CompanyBedford; Hikma Farmaceutica; United Biomedcl; Fresenius Kabi Usa; Lannett; Impax Labs; Akorn

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Adrenergic beta-2 Receptor Agonists

Compounds bind to and activate ADRENERGIC BETA-2 RECEPTORS. (See all compounds classified as Adrenergic beta-2 Receptor Agonists.)


Sympathomimetics

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)


Tocolytic Agents

Drugs that prevent preterm labor and immature birth by suppressing uterine contractions (TOCOLYSIS). Agents used to delay premature uterine activity include magnesium sulfate, beta-mimetics, oxytocin antagonists, calcium channel inhibitors, and adrenergic beta-receptor agonists. The use of intravenous alcohol as a tocolytic is now obsolete. (See all compounds classified as Tocolytic Agents.)


Bronchodilator Agents

Agents that cause an increase in the expansion of a bronchus or bronchial tubes. (See all compounds classified as Bronchodilator Agents.)


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04-Jan-2022
13-Apr-2025
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Looking for 23031-32-5 / Terbutaline Sulphate API manufacturers, exporters & distributors?

Terbutaline Sulphate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Terbutaline Sulphate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Terbutaline Sulphate manufacturer or Terbutaline Sulphate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Terbutaline Sulphate manufacturer or Terbutaline Sulphate supplier.

PharmaCompass also assists you with knowing the Terbutaline Sulphate API Price utilized in the formulation of products. Terbutaline Sulphate API Price is not always fixed or binding as the Terbutaline Sulphate Price is obtained through a variety of data sources. The Terbutaline Sulphate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Terbutaline Sulphate

Synonyms

Bricanyl, Terbutaline hemisulfate, Tert-butyl-[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]azanium;sulfate, Bricanyl turbuhaler, 576pu70y8e, 1,3-benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-, sulfate (2:1) (salt)

Cas Number

23031-32-5

About Terbutaline Sulphate

A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.

Terbutaline Sulphate Manufacturers

A Terbutaline Sulphate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Terbutaline Sulphate, including repackagers and relabelers. The FDA regulates Terbutaline Sulphate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Terbutaline Sulphate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Terbutaline Sulphate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Terbutaline Sulphate Suppliers

A Terbutaline Sulphate supplier is an individual or a company that provides Terbutaline Sulphate active pharmaceutical ingredient (API) or Terbutaline Sulphate finished formulations upon request. The Terbutaline Sulphate suppliers may include Terbutaline Sulphate API manufacturers, exporters, distributors and traders.

click here to find a list of Terbutaline Sulphate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Terbutaline Sulphate USDMF

A Terbutaline Sulphate DMF (Drug Master File) is a document detailing the whole manufacturing process of Terbutaline Sulphate active pharmaceutical ingredient (API) in detail. Different forms of Terbutaline Sulphate DMFs exist exist since differing nations have different regulations, such as Terbutaline Sulphate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Terbutaline Sulphate DMF submitted to regulatory agencies in the US is known as a USDMF. Terbutaline Sulphate USDMF includes data on Terbutaline Sulphate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Terbutaline Sulphate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Terbutaline Sulphate suppliers with USDMF on PharmaCompass.

Terbutaline Sulphate WC

A Terbutaline Sulphate written confirmation (Terbutaline Sulphate WC) is an official document issued by a regulatory agency to a Terbutaline Sulphate manufacturer, verifying that the manufacturing facility of a Terbutaline Sulphate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Terbutaline Sulphate APIs or Terbutaline Sulphate finished pharmaceutical products to another nation, regulatory agencies frequently require a Terbutaline Sulphate WC (written confirmation) as part of the regulatory process.

click here to find a list of Terbutaline Sulphate suppliers with Written Confirmation (WC) on PharmaCompass.

Terbutaline Sulphate GMP

Terbutaline Sulphate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Terbutaline Sulphate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Terbutaline Sulphate GMP manufacturer or Terbutaline Sulphate GMP API supplier for your needs.

Terbutaline Sulphate CoA

A Terbutaline Sulphate CoA (Certificate of Analysis) is a formal document that attests to Terbutaline Sulphate's compliance with Terbutaline Sulphate specifications and serves as a tool for batch-level quality control.

Terbutaline Sulphate CoA mostly includes findings from lab analyses of a specific batch. For each Terbutaline Sulphate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Terbutaline Sulphate may be tested according to a variety of international standards, such as European Pharmacopoeia (Terbutaline Sulphate EP), Terbutaline Sulphate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Terbutaline Sulphate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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