A 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one CEP of the European Pharmacopoeia monograph is often referred to as a 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one Certificate of Suitability (COS). The purpose of a 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one to their clients by showing that a 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one CEP has been issued for it. The manufacturer submits a 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one CEP (COS) as part of the market authorization procedure, and it takes on the role of a 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one CEP holder for the record. Additionally, the data presented in the 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one DMF.
A 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.
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