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1. Furaldehyde
1. 2-furaldehyde
2. Furan-2-carbaldehyde
3. 98-01-1
4. 2-furancarboxaldehyde
5. Furaldehyde
6. Furfuraldehyde
7. Fural
8. 2-formylfuran
9. 2-furanaldehyde
10. 2-furancarbonal
11. 2-furfural
12. Furancarbonal
13. Furfurole
14. Furfurylaldehyde
15. 2-furfuraldehyde
16. Pyromucic Aldehyde
17. Furale
18. Furole
19. Furol
20. 2-furylaldehyde
21. 2-furylcarboxaldehyde
22. 2-furyl-methanal
23. Artificial Ant Oil
24. Furfurale
25. Artificial Oil Of Ants
26. Furan-2-carboxaldehyde
27. Furyl-methanal
28. 2-furylmethanal
29. 2-furil-metanale
30. 2-furancarbaldehyde
31. Fufural
32. Alpha-furole
33. 2-formylofuran
34. Nci-c56177
35. 2-formyl Furan
36. Furan-2-aldehyde
37. 2-furankarbaldehyd
38. Rcra Waste Number U125
39. Alpha-furfuraldehyde
40. Fema No. 2489
41. Furaldehydes
42. .alpha.-furole
43. Nsc 8841
44. Mfcd00003229
45. Chebi:34768
46. Dj1hgi319p
47. 2-furancarboxaldehyde, Homopolymer
48. Bran Oil
49. Nsc-8841
50. Furane-2-carbaldehyde
51. Ncgc00091328-01
52. Quakeral
53. Dsstox_cid_647
54. Dsstox_rid_75709
55. Dsstox_gsid_20647
56. Furfural (natural)
57. Ant Oil, Artificial
58. Furfurale [italian]
59. Caswell No. 466
60. 2-formylofuran [polish]
61. 2-furankarbaldehyd [czech]
62. Cas-98-01-1
63. 2-furil-metanale [italian]
64. 25067-38-3
65. Ccris 1044
66. Hsdb 542
67. Einecs 202-627-7
68. Un1199
69. Rcra Waste No. U125
70. Unii-dj1hgi319p
71. Epa Pesticide Chemical Code 043301
72. Brn 0105755
73. Furfuralu
74. A-furfuraldehyde
75. Qo Furfural
76. Ai3-04466
77. A-furole
78. 2-furanal
79. Ant Oil
80. Furfural Acs Grade
81. Furan-2 Carbaldehyde
82. Furfural, 99%
83. 2-furancarboxyaldehyde
84. 2-furaldehyde, 8ci
85. 2-furan-carboxaldehyde
86. 2-furanocarboxyaldehyde
87. Furfural [fhfi]
88. Furfural [hsdb]
89. Furfural [iarc]
90. Furfural [inci]
91. Furfuraldehyde(furfural)
92. Furfural [fcc]
93. Furfural [mi]
94. 2-furylaldehyde Xypropane
95. Wln: T5oj Bvh
96. Ec 202-627-7
97. 5-17-09-00292 (beilstein Handbook Reference)
98. Bidd:er0698
99. Furfural, Acs Reagent, 99%
100. Chembl189362
101. Qspl 006
102. Qspl 102
103. Dtxsid1020647
104. Fema 2489
105. Furan-2-carbaldehyde (furfural)
106. Nsc8841
107. Furfural, >=98%, Fcc, Fg
108. Furfural, For Synthesis, 98.0%
109. Str00358
110. Zinc3861345
111. Tox21_111114
112. Tox21_202191
113. Tox21_300170
114. Bdbm50486229
115. Furaldehydes [un1199] [poison]
116. Stl283124
117. Akos000118907
118. Am81812
119. Furfural 100 Microg/ml In Cyclohexane
120. Furfural, Analytical Reference Material
121. Furfural 100 Microg/ml In Acetonitrile
122. Furfural, Natural, >=98%, Fcc, Fg
123. Furfural, Saj First Grade, >=99.0%
124. Ncgc00091328-02
125. Ncgc00091328-03
126. Ncgc00091328-04
127. Ncgc00253954-01
128. Ncgc00259740-01
129. Bp-31002
130. Furfural 1000 Microg/ml In Acetonitrile
131. Db-003668
132. Cs-0015696
133. F0073
134. Ft-0612462
135. A845786
136. Q412429
137. F1294-0048
138. Furfural; Furfuraldehyde; Furfurol; 2-furaldehyde; 2-furancarboxaldehyde; Furan-2-carboxaldehyde
| Molecular Weight | 96.08 g/mol |
|---|---|
| Molecular Formula | C5H4O2 |
| XLogP3 | 0.4 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 96.021129366 g/mol |
| Monoisotopic Mass | 96.021129366 g/mol |
| Topological Polar Surface Area | 30.2 Ų |
| Heavy Atom Count | 7 |
| Formal Charge | 0 |
| Complexity | 70.5 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Analysis of expired air of volunteers exposed to vapor showed after termination of exposure very small proportion (less than 1%) of retained furfural is eliminated by lungs. It is metabolized very rapidly. Half-life is about 2 to 2.5 hours. No free furoic acid found. This compound enters the body also percutaneously. At 15 minutes contamination of 1 hand (up to the wrist), approximately the same amount of furfural is absorbed as would be retained at an 8 hour (or 4 hour) inspiration of air in concentration equaling maximum allowable concentration.
PMID:649206 Flek J, Sedivec V; Int Arch Occup Environ Health 41 (3): 159-68 (1978)
The liver is the primary target for furfural toxicity in rats and mice.
Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additives Series 30: Furfural (1993). Available from, as of February 14, 2006: https://www.inchem.org/documents/jecfa/jecmono/v30je16.htm
Furfural is well absorbed after administration by any route. In rats, 85% of C14-furfural administered by gavage in corn oil was recovered in urine within 72 hours. ... After oral administration, furfural is rapidly absorbed from the gastrointestinal tract and distributed to the tissues, principally the liver and kidney.
Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additives Series 42: Furfural (1993). Available from, as of February 14, 2006: https://www.inchem.org/documents/jecfa/jecmono/v042je03.htm
The comparative metabolism and disposition of furfural (FAL) and furfuryl alcohol (FOL) /in male Fisher 344 rats/ were investigated following oral administration of approximately 0.001, 0.01, and 0.1 of the LD50, corresponding to approximately 0.127, 1.15, and 12.5 mg/kg for FAL and 0.275, 2.75, and 27.5 mg/kg for FOL. At all doses studied, at least 86-89% of the dose of FAL or FOL was absorbed from the gastrointestinal tract. FAL and FOL were extensively metabolized prior to excretion. The major route of excretion was in urine, where 83-88% of the dose was excreted, whereas 2-4% was excreted in the feces. Approximately 7% of the dose from rats treated with FAL at 12.5 mg/kg was exhaled as 14CO2. At 72 hr following administration, the pattern of tissue distribution of radioactivity was similar for both FAL and FOL. Liver and kidney contained the highest, and brain the lowest concentrations of radioactivity. Generally, the concentrations of radioactivity in tissues were proportional to the dose. Almost all of the urinary radioactivity was tentatively identified. No FAL or FOL was detected in urine.
PMID:1352210 Nomeir AA et al; Drug Metab Dispos 20 (2): 198-204 (1992)
The fate of furfural (2-furancarboxaldehyde) was investigated in male and female Fischer 344 (F344) rats given single oral doses of 1, 10 and 60 mg/kg and male and female CD1 mice given 1, 20 and 200 mg/kg [carbonyl-14C]furfural. There was a very high recovery (more than 90% of dose) of radioactivity in all dose groups in 72 hr. The major route of elimination was by the urine, with much smaller amounts present in the faeces and exhaled as 14CO2. The residue in the carcass after 72 hr was less than 1% of the administered dose.
PMID:7959443 Parkash MK, Caldwell J; Food Chem Toxicol 32 (10): 887-95 (1994)
Furfural is metabolized primarily by oxidation of the aldehyde function in rats and mice. Oxidation yields furoic acid, which, as the coenzyme A (CoA) thioester, is either conjugated with glycine and excreted or condensed with acetyl CoA to form the chain-lengthened metabolite 2-furanacryloyl CoA. 2-furanacryloyl CoA conjugates with glycine and and is excreted primarily in the urine. In rats and mice, furoic acid appears to decarboxylate to a very minor extent (approximately 1%) via oxidation of the furan ring to yield carbon dioxide ... .
Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additives Series 42: Furfural (1993). Available from, as of February 14, 2006: https://www.inchem.org/documents/jecfa/jecmono/v042je03.htm
The aldehyde group is converted to an acid and this in turn is conjugated with glycine. In dogs and rabbits, furoic acid, furoyl glycine, and furfuracryluric acid are excreted.
Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 2665
It is metabolized very rapidly. Chief metabolite is furoylglycine, side metabolite is 2-furanacryluric acid. No furoic acid found.
PMID:649206 Flek J, Sedivec V; Int Arch Occup Environ Health 41 (3): 159-68 (1978)
Furfural and its metabolite furoylglycine were extracted from urine. About 60% of furfural dose orally admin to rats was recovered in urine as furoylglycine, and no urinary furfural was detected.
Jodynis-Liebert J, Laboda K; Bromatol Chem Toksykol 15 (1-2): 61-6 (1982)
For more Metabolism/Metabolites (Complete) data for FURFURAL (6 total), please visit the HSDB record page.
Analysis of expired air of volunteers exposed for 8 hours to vapor showed half-life is about 2 to 2.5 hours.
PMID:649206 Flek J, Sedivec V; Int Arch Occup Environ Health 41 (3): 159-68 (1978)
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PharmaCompass offers a list of 2-Furaldehyde API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right 2-Furaldehyde manufacturer or 2-Furaldehyde supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred 2-Furaldehyde manufacturer or 2-Furaldehyde supplier.
PharmaCompass also assists you with knowing the 2-Furaldehyde API Price utilized in the formulation of products. 2-Furaldehyde API Price is not always fixed or binding as the 2-Furaldehyde Price is obtained through a variety of data sources. The 2-Furaldehyde Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A 2-Furaldehyde manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of 2-Furaldehyde, including repackagers and relabelers. The FDA regulates 2-Furaldehyde manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. 2-Furaldehyde API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A 2-Furaldehyde supplier is an individual or a company that provides 2-Furaldehyde active pharmaceutical ingredient (API) or 2-Furaldehyde finished formulations upon request. The 2-Furaldehyde suppliers may include 2-Furaldehyde API manufacturers, exporters, distributors and traders.
2-Furaldehyde Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of 2-Furaldehyde GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right 2-Furaldehyde GMP manufacturer or 2-Furaldehyde GMP API supplier for your needs.
A 2-Furaldehyde CoA (Certificate of Analysis) is a formal document that attests to 2-Furaldehyde's compliance with 2-Furaldehyde specifications and serves as a tool for batch-level quality control.
2-Furaldehyde CoA mostly includes findings from lab analyses of a specific batch. For each 2-Furaldehyde CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
2-Furaldehyde may be tested according to a variety of international standards, such as European Pharmacopoeia (2-Furaldehyde EP), 2-Furaldehyde JP (Japanese Pharmacopeia) and the US Pharmacopoeia (2-Furaldehyde USP).
