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WuXi AppTec Inc.
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Country
Country
China
Address
Address
WuXi AppTec 288 Fute Zhong Road Waigaoqiao Free Trade Zone Shanghai 200131, China
Telephone
Telephone
+86 (21) 5046-1111 
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Linkedin
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Under the agreement, WuXi ATU will serve as a cell processing manufacturing partner for the planned global clinical development of CABA-201, a 4-1BB-containing fully human CD19-CAR T, in systemic lupus erythematosus and idiopathic inflammatory myopathies, or myositis.


Lead Product(s): CABA-201

Therapeutic Area: Immunology Product Name: CABA-201

Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Cabaletta Bio

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement August 22, 2023

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Through the partnership, Interius will leverage WuXi ATU's CTDMO platform for Good Manufacturing Process (GMP) manufacturing of Phase I clinical product and will advance INT-2104 in vivo CART program for B cell malignancies to the clinic.


Lead Product(s): INT-2104

Therapeutic Area: Oncology Product Name: INT-2104

Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Interius BioTherapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership May 08, 2023

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PAS-004 (CIP-137401) is a small molecule allosteric inhibitor of MEK 1/2 in the Ras-Raf-MEK-ERK signaling pathway, which plays critical roles in the regulation of diverse cellular activities, including cell proliferation, survival, differentiation, and motility.


Lead Product(s): CIP-137401

Therapeutic Area: Genetic Disease Product Name: PAS-004

Highest Development Status: IND EnablingProduct Type: Small molecule

Recipient: Pasithea Therapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement January 18, 2023

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Under this agreement, WuXi ATU will license to Janssen its TESSA™ technology, a high-performance system that can produce 10 times more adeno-associated viral (AAV) vectors than traditional AAV manufacturing systems.


Lead Product(s): Aav Vectors

Therapeutic Area: Technology Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Johnson & Johnson Innovative Medicine

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement August 11, 2022

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TFC-1326 has the potential to replace or supplement dermal filler injections to treat the static wrinkles. TFC-1326 with its unique mechanism of action is revolutionary in the aesthetic skin care space.


Lead Product(s): TFC-1326

Therapeutic Area: Dermatology Product Name: TFC-1326

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Sirona Biochem Corp

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement June 22, 2022

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Orbit gains access to WuXi AppTec’s expertise in peptide optimisation, peptide production and manufacturing to help its Partners obtain clinically relevant data packs and materials in a rapid time frame.


Lead Product(s): Undisclosed

Therapeutic Area: Technology Product Name: Undisclosed

Highest Development Status: Discovery PlatformProduct Type: Peptide

Partner/Sponsor/Collaborator: Orbit Discovery

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership March 07, 2022

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Qualigen Therapeutics has signed a contract with STA Pharmaceutical, a subsidiary of WuXi AppTec, for GMP production of AS1411, Qualigen's lead drug candidate for the treatment of COVID-19 and other viral diseases, for potential clinical trials.


Lead Product(s): AS1411

Therapeutic Area: Infections and Infectious Diseases Product Name: AS1411

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Qualigen Therapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement November 05, 2020

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Simcha’s lead program involves a customized variant of interleukin-18 (IL-18), a cytokine with potent antitumor effects, developed in the lab of Scientific Founder Aaron Ring, M.D., Ph.D., Assistant Professor of Immunobiology at the Yale School of Medicine.


Lead Product(s): ST-067

Therapeutic Area: Oncology Product Name: ST-067

Highest Development Status: PreclinicalProduct Type: Large molecule

Recipient: Simcha Therapeutics

Deal Size: $25.0 million Upfront Cash: Undisclosed

Deal Type: Series A Financing June 24, 2020

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