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Seres Therapeutics
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U.S.A
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200 Sidney Street Cambridge, MA 02139
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617-945-9626

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Vowst (fecal microbiota spores, live-brpk) is approved by FDA as the first orally administered microbiota-based therapeutic for the prevention of recurrent C. difficile infection (CDI).


Lead Product(s): Fecal Microbiota Spores Live-brpk

Therapeutic Area: Infections and Infectious Diseases Product Name: Vowst

Highest Development Status: ApprovedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Nestle Health Sciences SA

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 05, 2023

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The agreement aimed to jointly commercialize Vowst (fecal microbiota spores, live-brpk), an orally administered microbiota-based therapeutic to prevent recurrence of C. difficile Infection in adults following antibiotic treatment for recurrent CDI, following its FDA Approval.


Lead Product(s): Fecal Microbiota Spores Live-brpk

Therapeutic Area: Infections and Infectious Diseases Product Name: Vowst

Highest Development Status: ApprovedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Nestle Health Sciences SA

Deal Size: $525 million Upfront Cash: $175 million

Deal Type: Agreement May 30, 2023

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The financing will support the commercial launch of Vowst, the first orally administered microbiota-based therapeutic to prevent recurrence of C. difficile Infection in adults following antibacterial treatment for recurrent CDI and to fund company's pipeline development.


Lead Product(s): Fecal Microbiota Spores Live-brpk

Therapeutic Area: Infections and Infectious Diseases Product Name: Vowst

Highest Development Status: ApprovedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Oaktree Capital Management

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Financing April 27, 2023

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Vowst (fecal microbiota spores, live-brpk) is approved by FDA as the first orally administered microbiota-based therapeutic for the prevention of recurrent C. difficile infection (CDI).


Lead Product(s): Fecal Microbiota Spores Live-brpk

Therapeutic Area: Infections and Infectious Diseases Product Name: Vowst

Highest Development Status: ApprovedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Nestle Health Sciences SA

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 26, 2023

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SER-109 is an oral microbiome therapeutic candidate consisting consortium of highly purified Firmicutes spores. It is designed to prevent further recurrences of CDI by modulating the disrupted microbiome to a state that resists C. difficile colonization and growth.


Lead Product(s): Firmicute Species Bacterial Spores

Therapeutic Area: Infections and Infectious Diseases Product Name: SER-109

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 14, 2023

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SER-155 composition aims to decrease the colonization and abundance of bacterial pathogens, and to enhance epithelial barrier integrity in the GI tract to both reduce the likelihood of pathogen translocation and decrease the incidence of bloodstream infections.


Lead Product(s): SER-155,Vancomycin Hydrochloride

Therapeutic Area: Immunology Product Name: SER-155

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 08, 2023

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SER-109 (Firmicute Species Bacterial Spores) is an oral microbiome therapeutic candidate consisting of a consortium of highly purified Firmicutes spores, which normally live in a healthy microbiome.


Lead Product(s): Firmicute Species Bacterial Spores

Therapeutic Area: Infections and Infectious Diseases Product Name: SER-109

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 26, 2022

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Details:

SER-109 is an oral microbiome therapeutic candidate consisting of a consortium of highly purified Firmicutes spores, which normally live in a healthy microbiome.


Lead Product(s): Firmicute Species Bacterial Spores

Therapeutic Area: Infections and Infectious Diseases Product Name: SER-109

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 19, 2022

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Clinical and preclinical data for SER-109, (Firmicute Species Bacterial Spores) support Seres’ development of microbiome therapeutics to reduce the incidence of antibiotic-resistant bacterial infections.


Lead Product(s): Firmicute Species Bacterial Spores

Therapeutic Area: Infections and Infectious Diseases Product Name: SER-109

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 08, 2022

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Details:

SER-109 is an oral microbiome therapeutic candidate consisting of a consortium of highly purified Firmicutes spores, which normally live in a healthy microbiome.


Lead Product(s): SER-109

Therapeutic Area: Infections and Infectious Diseases Product Name: SER-109

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 07, 2022

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