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SEARCHLIGHT PHARMA INC
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Through the acquisition, Apotex will commercialize Twyneo (tretinoin), a retinoic acid receptor agonist in combination with Benzoyl Peroxide indicated for the topical treatment of acne vulgaris in adults and pediatric patients 9 years of age and older.


Lead Product(s): Tretinoin,Benzoyl Peroxide

Therapeutic Area: Dermatology Product Name: Twyneo

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Apotex Inc

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition April 02, 2024

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Under the terms of the agreement, Searchlight will have sales and marketing rights for DONESTA® in Canada. DONESTA (estetrol) phase 3 clinical program, which demonstrated a meaningful reduction in the frequency and severity of vasomotor symptoms compared to placebo.


Lead Product(s): Estetrol

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Product Name: Donesta

Highest Development Status: Phase IIIProduct Type: Small molecule

Recipient: Mithra Pharmaceuticals

Deal Size: $17.9 million Upfront Cash: Undisclosed

Deal Type: Licensing Agreement October 26, 2023

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Under the agreement, Searchlight will have the Canadian rights to Donesta, a next generation orally administered Estetrol (E4)-based hormone therapy product, for the treatment of the symptoms of menopause.


Lead Product(s): Estetrol

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Product Name: Donesta

Highest Development Status: Phase IIIProduct Type: Small molecule

Recipient: Mithra Pharmaceuticals

Deal Size: $18.7 million Upfront Cash: Undisclosed

Deal Type: Licensing Agreement July 31, 2023

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Under the agreement, Searchlight Pharma will be responsible for obtaining and maintaining any regulatory approvals required to market and sell Twyneo (tretinoin), used for acne vulgaris and Epsolay (benzoyl peroxide), used for inflammatory lesions of rosacea, in Canada.


Lead Product(s): Tretinoin,Benzoyl Peroxide

Therapeutic Area: Dermatology Product Name: Twyneo

Highest Development Status: ApprovedProduct Type: Small molecule

Recipient: Sol-Gel Technologies

Deal Size: $11.0 million Upfront Cash: Undisclosed

Deal Type: Licensing Agreement June 06, 2023

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