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Otsuka America Pharmaceutical, Inc.
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U.S.A
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2440 Research Blvd, Rockville, MD 20850
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+1 (301) 990-0030
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SEP-363856 (ulotaront) is a TAAR1 agonist with 5-HT1A agonist activity, is currently under investigation for the treatment of schizophrenia, generalized anxiety disorder and the adjunctive treatment of MDD with additional indications under consideration.


Lead Product(s): Ulotaront

Therapeutic Area: Psychiatry/Psychology Product Name: SEP-363856

Highest Development Status: Phase II/ Phase IIIProduct Type: Small molecule

Recipient: Sunovion Pharmaceuticals

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 26, 2023

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Brexpiprazole (Rexulti) is an adjunctive therapy to antidepressants in adults with major depressive disorder and as a treatment for schizophrenia in adults and children ages 13 years and older.


Lead Product(s): Brexpiprazole

Therapeutic Area: Psychiatry/Psychology Product Name: Rexulti

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: H. Lundbeck AS

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 01, 2022

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Avanir and Otsuka have always shared a deep commitment to advancing solutions that improve the lives of patients by Nuedexta (dextromethorphan hydrobromide and quinidine sulfate).


Lead Product(s): Deudextromethorphan Hydrobromide,Quinidine sulphate

Therapeutic Area: Neurology Product Name: AVP-786

Highest Development Status: Phase IIIProduct Type: Small molecule

Recipient: AVANIR PHARMS

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Merger October 24, 2022

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