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Milestone Pharmaceuticals
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1111 Dr.-Frederik-Philips Blvd., Suite 420 Saint-Laurent, (Quebec) H4M 2X6 Canada
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(514) 336-0444
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MSP-2017 (etripamil) is a fast-acting, intranasally administered calcium-channel blocker, which is being evaluated for the treatment of Paroxysmal Supraventricular Tachycardia.


Lead Product(s): Etripamil

Therapeutic Area: Cardiology/Vascular Diseases Product Name: MSP-2017

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 28, 2024

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Milestone intends to use the net proceeds from the Offering to continue the development of Cardamyst (etripamil) in its lead indication of paroxysmal supraventricular tachycardia.


Lead Product(s): Etripamil

Therapeutic Area: Cardiology/Vascular Diseases Product Name: Cardamyst

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Piper Sandler & Co

Deal Size: $30.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering February 29, 2024

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Milestone intends to use the net proceeds from the offering to continue the development of MSP-2017 (etripamil) in its lead indication of paroxysmal supraventricular tachycardia.


Lead Product(s): Etripamil

Therapeutic Area: Cardiology/Vascular Diseases Product Name: MSP-2017

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Piper Sandler

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Public Offering February 28, 2024

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Details:

MSP-2017 (etripamil) is a fast-acting, intranasally administered calcium-channel blocker, which is being evaluated for the treatment of Paroxysmal Supraventricular Tachycardia.


Lead Product(s): Etripamil

Therapeutic Area: Cardiology/Vascular Diseases Product Name: MSP-2017

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 26, 2024

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MSP-2017 (etripamil) is a novel calcium channel blocker. It is under phase 3 clinical development for the treatment of paroxysmal supraventricular tachycardia.


Lead Product(s): Etripamil

Therapeutic Area: Cardiology/Vascular Diseases Product Name: MSP-2017

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 26, 2023

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MSP-2017 (etripamil) is Milestone's lead investigational product. It is a novel calcium channel blocker nasal spray being developed for elevated and often highly symptomatic heart-rate attacks associated with PSVT and atrial fibrillation with a rapid ventricular rate.


Lead Product(s): Etripamil

Therapeutic Area: Cardiology/Vascular Diseases Product Name: MSP-2017

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 24, 2023

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The net proceeds from the financing will be used to support the advancement of MSP-2017 (etripamil), a novel calcium channel blocker nasal spray, for paroxysmal supraventricular tachycardia.


Lead Product(s): Etripamil

Therapeutic Area: Cardiology/Vascular Diseases Product Name: MSP-2017

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: RTW Investments

Deal Size: $125.0 million Upfront Cash: Undisclosed

Deal Type: Financing March 28, 2023

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Details:

MSP-2017 (etripamil) is a calcium channel antagonist potentially for the treatment of paroxysmal supraventricular tachycardia. It is designed to be a rapid-response therapy for elevated and often highly symptomatic heart rate attacks associated with PSVT and AFib-RVR.


Lead Product(s): Etripamil

Therapeutic Area: Cardiology/Vascular Diseases Product Name: MSP-2017

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 06, 2023

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Details:

MSP-2017 (etripamil), a new chemical entity, is a novel calcium channel blocker designed to be a rapid-response therapy for episodic cardiovascular conditions.


Lead Product(s): Etripamil

Therapeutic Area: Cardiology/Vascular Diseases Product Name: MSP-2017

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 25, 2022

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Details:

MSP-2017 (etripamil), is a novel calcium channel blocker designed to be a rapid-response therapy for episodic cardiovascular conditions. As a nasal spray that is self-administered by the patient.


Lead Product(s): Etripamil

Therapeutic Area: Cardiology/Vascular Diseases Product Name: MSP-2017

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Medpace, Inc

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 17, 2022

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