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Meiji Seika Pharma
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4-16, Kyobashi 2-chome, Chuo-ku, Tokyo 104-800
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A novel anti-PD-1 agonist monoclonal antibody, which inhibits the function of PD-1 (anti-PD-1 blocking antibodies) leading in enhanced anti-tumor immunity.


Lead Product(s): Monoclonal Antibody

Therapeutic Area: Immunology Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Foundation for Biomedical Research and Innovation at Kobe

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 16, 2023

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In non-clinical studies, ME3183, a selective phosphodiesterase-4 (PDE4) inhibitor, showed greater anti-inflammatory effect and its inhibitory effect on TNF-α production was approximately 30-fold greater than the existing orally-available PDE4 inhibitor for psoriasis.


Lead Product(s): ME3183

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ME3183

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 07, 2022

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ME3183 is an orally-available and selective inhibitor for phosphodiesterase 4 (PDE4) discovered by Meiji. In the study, ME3183 has been shown to be safe and well-tolerated across the doses tested.


Lead Product(s): ME3183

Therapeutic Area: Dermatology Product Name: ME3183

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 24, 2021

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Under the terms of the agreement, Intas was granted the exclusive license rights to market DMB-3115 worldwide, excluding Japan, Korea and certain countries in Asia.


Lead Product(s): Ustekinumab

Therapeutic Area: Dermatology Product Name: DMB-3115

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Intas Pharmaceuticals

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement July 21, 2021

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A single subcutaneous injection of DMB3115 in healthy volunteers was well tolerated. The reported adverse events corresponded with the known safety profile of ustekinumab.


Lead Product(s): Ustekinumab

Therapeutic Area: Dermatology Product Name: DMB-3115

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Dong-A Socio Holdings

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 21, 2021

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Eisai will take over by transfer the manufacturing and marketing approval of Equfina from Meiji. Eisai, as the manufacturer and distributor of Equfina in Japan, will continue to provide information on the proper usage of Equfina.


Lead Product(s): Safinamide Mesylate

Therapeutic Area: Neurology Product Name: Equfina

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Eisai

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement September 07, 2020

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HUYABIO will complete the development of HBI-8000 for PTCL and ATL in Japan for commercialization by Meiji who will hold exclusive sales and marketing rights.


Lead Product(s): Tucidinostat

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Recipient: HUYA Bioscience International

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration January 08, 2020

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