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Trecondyv (treosulfan) is used to prepare patients for blood stem cell transplant. Trecondyv destroys bone marrow cells. This allows for the transplant of new blood stem cells from a donor which leads to the production of healthy blood cells.


Lead Product(s): Treosulfan,Fludarabine Phosphate

Therapeutic Area: Oncology Product Name: Trecondyv

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 19, 2022

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Study found event-free survival and overall survival superior after Trecondyv (treosulfan) compared to RIC busulfan, also found non-relapse mortality lower in treosulfan arm than busulfan arm.


Lead Product(s): Treosulfan,Fludarabine Phosphate

Therapeutic Area: Oncology Product Name: Trecondyv

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Medac

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 06, 2022

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Trecondyv (treosulfan), preparative regimen for allogeneic hematopoietic stem cell transplantation to be used in combination with fludarabine, is medication given to people before they have bone marrow transplant from a donor allogeneic hematopoietic stem cell transplantation


Lead Product(s): Treosulfan,Fludarabine Phosphate

Therapeutic Area: Oncology Product Name: Trecondyv

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 25, 2022

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The resubmission includes additional clinical data and statistical analysis relating to previously-completed phase 3 clinical trial of Treosulfan as well as an update of integrated summary of safety, which FDA had requested in their July 2021 Complete Response Letter to medac.


Lead Product(s): Treosulfan,Fludarabine Phosphate

Therapeutic Area: Oncology Product Name: Treosulfan

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 22, 2022

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Treosulfan will be marketed in Canada under the brand name Trecondyv® and indicated in combination with fludarabine as part of a conditioning treatment prior to allogeneic hematopoietic stem cell transplantation (“allo-HSCT”).


Lead Product(s): Treosulfan,Fludarabine Phosphate

Therapeutic Area: Oncology Product Name: Trecondyv

Highest Development Status: ApprovedProduct Type: Small molecule

Recipient: Medac

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement July 12, 2021

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Medac intends to leverage its strong, existing commercial infrastructure in the United States to address the underserved allo-HSCT market through its commercialization of treosulfan.


Lead Product(s): Treosulfan,Fludarabine Phosphate

Therapeutic Area: Oncology Product Name: Trecondi

Highest Development Status: ApprovedProduct Type: Small molecule

Recipient: Medac

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement February 02, 2021

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Triamcinolone Hexacetonide is a longest-acting corticosteroid for intra articular injection. The companies have agreed to a small upfront fee along with milestone payments at the time of FDA approval, at commercial product launch, and upon certain sales milestones.


Lead Product(s): Triamcinolone Acetonide

Therapeutic Area: Immunology Product Name: Undisclosed

Highest Development Status: ApprovedProduct Type: Small molecule

Recipient: Ethypharm

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement December 18, 2020

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Medexus reached the 50% enrollment target in its Phase 4 clinical trial investigating IXINITY® as a prophylactic treatment for pediatric patients under 12 years of age with hemophilia B.


Lead Product(s): Recombinant coagulation factor IX

Therapeutic Area: Genetic Disease Product Name: Ixinity

Highest Development Status: Phase IVProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 16, 2020

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Triamcinolone Hexacetonide Injectable Suspension 20 mg/mL (TH) has been approved for inclusion as a general benefit (open listing) on the List of Medications- Institutions administered by the Régie de l’assurance maladie du Québec (RAMQ), effective August 19, 2020.


Lead Product(s): Triamcinolone Acetonide

Therapeutic Area: Immunology Product Name: Undisclosed

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 24, 2020

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TH is the longest acting corticosteroid for intra-articular injection, often lasting twice as long as comparator products.


Lead Product(s): Triamcinolone Acetonide

Therapeutic Area: Immunology Product Name: Undisclosed

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 09, 2020

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