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Belbuca-Generic (buprenorphine) is a partial agonist at the mu-opioid receptor and an antagonist at the kappa-opioid receptor. It is indicated to manage chronic pain severe. It has received CRL from FDA for its resubmitted ANDA.


Lead Product(s): Buprenorphine

Therapeutic Area: Neurology Product Name: Belbuca-Generic

Highest Development Status: Phase IIIProduct Type: Small molecule

Recipient: Xiromed

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 05, 2024

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The net proceeds will be utilized for the commercialisation of Exordia (tadalafil), it comprises one of the three main PDE5 inhibitors. It is being evaluated in the treatment of erectile dysfunction.


Lead Product(s): Tadalafil

Therapeutic Area: Psychiatry/Psychology Product Name: Exordia

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Digital Offering, LLC

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Public Offering February 20, 2024

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VersaFilm® (montelukast) is a leukotriene receptor antagonist, which is completed patient enrollment in the ongoing Phase 2a clinical trial in patients with mild to moderate Alzheimer’s Disease.


Lead Product(s): Montelukast Sodium

Therapeutic Area: Neurology Product Name: Montelukast VersaFilm

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 14, 2023

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The agreement aims for the co-development and commercialization of cannabinoid-infused VersaFilm® products, including CBD VersaFilm (cannabinoid), a unique drug opportunity for the treatment of neurodegenerative diseases of the brain.


Lead Product(s): Montelukast Sodium

Therapeutic Area: Neurology Product Name: CBD VersaFilm

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Tilray

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement November 06, 2023

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Rizafilm (rizatriptan) binds with high affinity to human cloned 5-HT1B/1D receptors. It has received FDA approval for the Treatment of acute migraine. It is approved in EU under the name rizaport.


Lead Product(s): Rizatriptan Benzoate

Therapeutic Area: Neurology Product Name: Rizafilm

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Gensco Pharma

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 21, 2023

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Buprenorphine is a partial agonist at the mu-opioid receptor and an antagonist at the kappa-opioid receptor. It is indicated to manage chronic pain severe enough to require daily, around-the-clock, long-term treatment with an opioid.


Lead Product(s): Buprenorphine

Therapeutic Area: Neurology Product Name: Belbuca-Generic

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 19, 2023

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VersaFilm® (montelukast) is a leukotriene receptor antagonist, which is completed patient enrollment in the ongoing Phase 2a clinical trial in patients with mild to moderate Alzheimer’s Disease.


Lead Product(s): Montelukast Sodium

Therapeutic Area: Neurology Product Name: Montelukast VersaFilm

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 01, 2023

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The agreement aims to investigate the use of IntelGenx’s Montelukast VersaFilm, a leukotriene receptor antagonist, for the treatment of Parkinson’s Disease.


Lead Product(s): Montelukast Sodium

Therapeutic Area: Neurology Product Name: Montelukast VersaFilm

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: Karolinska University Hospital

Deal Size: $2.0 million Upfront Cash: Undisclosed

Deal Type: Agreement July 25, 2023

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Buprenorphine is a partial agonist at the mu-opioid receptor and an antagonist at the kappa-opioid receptor. It is indicated to manage chronic pain severe enough to require daily, around-the-clock, long-term treatment with an opioid.


Lead Product(s): Buprenorphine

Therapeutic Area: Neurology Product Name: Belbuca-Generic

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Xiromed

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 27, 2023

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Rizafilm (rizatriptan) binds with high affinity to human cloned 5-HT1B/1D receptors. It has received FDA approval for the Treatment of acute migraine. It is approved in EU under the name rizaport.


Lead Product(s): Rizatriptan Benzoate

Therapeutic Area: Neurology Product Name: Rizafilm

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 17, 2023

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