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Details:
ISP-001 (Iduronicrin Genleukocel-T) is the first product candidate developed using the company’s proprietary technique which is under phase 1 clinical development for the treatment of mucopolysaccharidosis type I (MPS I).
Lead Product(s): Iduronicrin Genleukocel-T
Therapeutic Area: Genetic Disease Product Name: ISP-001
Highest Development Status: Phase IProduct Type: Cell and Gene therapy
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable December 15, 2023
Details:
This funding will support a Phase I study to evaluate the safety and tolerability of ISP-001 (for delivery of alpha-L-iduronidase, or IDUA) in MPS I a rare, childhood genetic disease.
Lead Product(s): Iduronicrin Genleukocel-T
Therapeutic Area: Genetic Disease Product Name: ISP-001
Highest Development Status: Phase IProduct Type: Cell and Gene therapy
Partner/Sponsor/Collaborator: California Institute for Regenerative Medicine
Deal Size: $8.0 million Upfront Cash: Undisclosed
Deal Type: Funding January 27, 2023
Details:
ISP-001 (iduronicrin genleukocel-T) represents the first product candidate developed using the company’s proprietary technique for the treatment of mucopolysaccharidosis type I (MPS I).
Lead Product(s): Iduronicrin Genleukocel-T
Therapeutic Area: Genetic Disease Product Name: ISP-001
Highest Development Status: IND EnablingProduct Type: Cell and Gene therapy
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable September 01, 2022
Details:
The funding will support the development of its ISP- 002 (for delivery of iduronate sulfatase) program in mucopolysaccharidosis type II (MPS II), an inherited disease for which patients have limited options.
Lead Product(s): Iduronate Sulfatase
Therapeutic Area: Genetic Disease Product Name: ISP-002
Highest Development Status: IND EnablingProduct Type: Large molecule
Partner/Sponsor/Collaborator: California Institute for Regenerative Medicine
Deal Size: $4.0 million Upfront Cash: Undisclosed
Deal Type: Funding November 29, 2021