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Under the partnership, Glenmark and Pfizer will co‐market abrocitinib, a Janus kinase 1 (JAK1) inhibitor, provides rapid itch relief and sustained disease control in India under the brand names Jabryus and Cibinqo, respectively.
Lead Product(s): Abrocitinib
Therapeutic Area: Dermatology Product Name: Cibinqo
Highest Development Status: ApprovedProduct Type: Small molecule
Partner/Sponsor/Collaborator: Pfizer Inc
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Partnership January 31, 2024
Details:
The collaboration aims to accelerate new drug discovery in cancer treatment combining Ichnos' research and development proficiencies in novel biologics with those of Glenmark in new small molecules, including GRC 54276, to treat hematological malignancies and solid tumors.
Lead Product(s): GRC 54276,Pembrolizumab
Therapeutic Area: Oncology Product Name: GRC 54276
Highest Development Status: Phase IProduct Type: Small molecule
Recipient: Ichnos Sciences
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Collaboration January 30, 2024
Details:
Glenmark will be responsible for further developing, registering, and commercializing KN035 (envafolimab), approved in China for the treatment of adult patients with previously treated MSI-H or dMMR advanced solid tumor, in multiple geographies around the World.
Lead Product(s): Envafolimab
Therapeutic Area: Oncology Product Name: KN035
Highest Development Status: Phase IIProduct Type: Large molecule
Recipient: Jiangsu Alphamab
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Licensing Agreement January 25, 2024
Details:
Lirafit (liraglutide biosimilar) is a glucagon‐like peptide 1 receptor agonists (GLP‐1 RAs). It is now approved in India for the treatment of adult patients with type 2 diabetes mellitus.
Lead Product(s): Liraglutide
Therapeutic Area: Endocrinology Product Name: Lirafit
Highest Development Status: ApprovedProduct Type: Peptide
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable January 03, 2024
Details:
Zita DM contains the DPP4 inhibitor, Teneligliptin, the SGLT2 inhibitor, Dapagliflozin, and Metformin SR in a fixed dose. It must be taken once daily, under prescription, to improve glycemic control in patients with Type 2 diabetes.
Lead Product(s): Teneligliptin,Dapagliflozin,Metformin
Therapeutic Area: Endocrinology Product Name: Zita DM
Highest Development Status: ApprovedProduct Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable October 18, 2023
Details:
Under the agreements, Glenmark will receive from Cassiopea, the exclusive right to commercialize Winlevi (clascoterone cream), used on the skin (topical) to treat acne vulgaris in people 12 years of age and older, in 15 EU countries as well as in South Africa and the UK.
Lead Product(s): Clascoterone
Therapeutic Area: Dermatology Product Name: Winlevi
Highest Development Status: ApprovedProduct Type: Small molecule
Recipient: Cassiopea
Deal Size: Undisclosed Upfront Cash: $5.0 million
Deal Type: Licensing Agreement September 27, 2023
Details:
The product is the combination of calcipotriene hydrate as a synthetic vitamin D3 analog and betamethasone dipropionate as a synthetic corticosteroid. It is indicated for the topical treatment of plaque psoriasis.
Lead Product(s): Calcipotriol,Betamethasone Dipropionate
Therapeutic Area: Dermatology Product Name: Enstilar-Generic
Highest Development Status: ApprovedProduct Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 23, 2023
Details:
Prochlorperazine maleate inhibits the action of a chemical called dopamine in the brain by blocking D2 dopamine receptors in the brain. It can also block histaminergic, cholinergic, and noradrenergic receptors. It is indicated for the treatment of schizophrenia.
Lead Product(s): Prochlorperazine Maleate
Therapeutic Area: Psychiatry/Psychology Product Name: Compazine-Generic
Highest Development Status: ApprovedProduct Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 20, 2023
Details:
GRC 54276 is an orally available, small molecule hematopoietic progenitor kinase 1 (HPK1) inhibitor, which is designed to potentially enhance the patient’s own immune system to fight cancers like advanced solid tumors and lymphomas.
Lead Product(s): GRC 54276
Therapeutic Area: Oncology Product Name: GRC 54276
Highest Development Status: IND EnablingProduct Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 16, 2023
Details:
Clindamycin hydrochloride is a bacteriostatic which inhibits bacterial protein synthesis by binding to the 23S RNA of the 50S subunit of the ribosome.
Lead Product(s): Clindamycin Hydrochloride
Therapeutic Area: Infections and Infectious Diseases Product Name: Cleocin-Generic
Highest Development Status: ApprovedProduct Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 14, 2023
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